Testing effectiveness (Phase 2)WithdrawnNCT03760445What this trial is testingHDM201 Added to CT in R/R or Newly Diagnosed AMLWho this might be right forLeukemia, Myeloid, Acute Novartis Pharmaceuticals
Large-scale testing (Phase 3)Study completedNCT02421939What this trial is testingASP2215 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase (FLT3) MutationWho this might be right forLeukemia, Acute Myeloid (AML) Astellas Pharma Global Development, Inc. 371
Testing effectiveness (Phase 2)WithdrawnNCT03324243What this trial is testingCrenolanib With Fludarabine and Cytarabine in Pediatric Patients With Relapsed/Refractory FLT3-Mutated Acute Myeloid LeukemiaWho this might be right forRelapsed/Refractory FLT3-mutated AML Arog Pharmaceuticals, Inc.
Testing effectiveness (Phase 2)Ended earlyNCT04209725What this trial is testingCPX-351 (Vyxeos™) With Quizartinib for the Treatment of FLT3-ITD Mutation-Positive Acute Myeloid LeukemiaWho this might be right forLeukemia, Myeloid, Acute SCRI Development Innovations, LLC 1
Testing effectiveness (Phase 2)UnknownNCT03135054What this trial is testingCombination of Quizartinib and Omacetaxine Mepesuccinate for AML Carrying FLT3-ITDWho this might be right forAMLFLT3-ITD Mutation The University of Hong Kong 40
Testing effectiveness (Phase 2)Study completedNCT02984995What this trial is testingPhase 2 Study of Quizartinib in Participants With Acute Myeloid Leukemia (AML) FLT3 Internal Tandem Duplication (FLT3/ITD) MutationWho this might be right forLeukemia, Myeloid, Acute Daiichi Sankyo Co., Ltd. 37
Testing effectiveness (Phase 2)Looking for participantsNCT06022003What this trial is testingStudy Investigating the Efficacy and Safety of the Addition of Oral-azacitidine to Salvage Treatment by Gilteritinib in Subjects ≥18 Years of Age With Relapsed/Refractory FLT3-mutated Acute Myeloid LeukemiaWho this might be right forAML, AdultRefractory AMLRelapsed Adult AML+2 more French Innovative Leukemia Organisation 33
Early research (Phase 1)WithdrawnNCT05330377What this trial is testingGM-CLAG in Relapsed/Refractory FLT3-mutated AMLWho this might be right forAcute Myeloid Leukemia Ayman H Qasrawi
Testing effectiveness (Phase 2)Study completedNCT03170895What this trial is testingCombination of Sorafenib and Omacetaxine Mepesuccinate in Newly Diagnosed or Relapsed/Refractory AML Carrying FLT3-ITDWho this might be right forAMLFLT3-ITD Mutation The University of Hong Kong 5
Early research (Phase 1)Ended earlyNCT03552029What this trial is testingMilademetan Plus Quizartinib Combination Study in FLT3-ITD Mutant Acute Myeloid Leukemia (AML)Who this might be right forAcute Myeloid Leukemia Daiichi Sankyo 10
Early research (Phase 1)Looking for participantsNCT05546580What this trial is testingStudy of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+)Who this might be right forAcute Myeloid Leukemia, in RelapseAcute Myeloid Leukemia Refractory Oryzon Genomics S.A. 50
Large-scale testing (Phase 3)Not Yet RecruitingNCT05876832What this trial is testingXY0206 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory AML With FLT3-ITD-Mutation (ALIVE)Who this might be right forAcute Myeloid Leukemia With FLT3/ITD Mutation Shijiazhuang Yiling Pharmaceutical Co. Ltd 312
Not applicableNo Longer AvailableNCT03746912What this trial is testingExpanded Treatment Protocol for Adults With FLT3-ITD Mutated Relapsed or Refractory Acute Myeloid Leukemia (AML) to Receive QuizartinibWho this might be right forAcute Myeloid Leukemia With Gene Mutations Daiichi Sankyo
Testing effectiveness (Phase 2)Study completedNCT00030186What this trial is testingOpen Study of CEP-701 in Patients With Refractory Acute Myeloid Leukemia With FLT-3 MutationWho this might be right forLeukemia, Myeloid Cephalon 37
Early research (Phase 1)Looking for participantsNCT06222580What this trial is testingSNDX-5613 and Gilteritinib for the Treatment of Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia and Concurrent MLL-Rearrangement or NPM1 MutationWho this might be right forAcute Myeloid Leukemia With FLT3/ITD MutationAcute Myeloid Leukemia With KMT2A RearrangementAcute Myeloid Leukemia With NPM1 Mutation+2 more Uma Borate 30
Testing effectiveness (Phase 2)Ended earlyNCT05028751What this trial is testingEvaluate Lanraplenib (LANRA) in Combination With Gilteritinib in Participants With FLT3-mutated Relapsed or Refractory Acute Myeloid Leukemia (AML)Who this might be right forAcute Myeloid LeukemiaRelapsed Acute Myeloid LeukemiaRefractory Acute Myeloid Leukemia Kronos Bio 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT03793478What this trial is testingSafety and Efficacy of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of the BloodWho this might be right forAcute Myeloid Leukemia Daiichi Sankyo 65
Large-scale testing (Phase 3)UnknownNCT04716114What this trial is testingSKLB1028 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory (R/R) AML With FLT3-MutatedWho this might be right forAcute Myeloid Leukemia (AML) CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 315
Large-scale testing (Phase 3)Active Not RecruitingNCT03182244What this trial is testingASP2215 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase 3 (FLT3) MutationWho this might be right forAML With FLT3 Mutation Astellas Pharma Inc 276
Testing effectiveness (Phase 2)Temporarily pausedNCT04278768What this trial is testingDose Escalation/ Expansion Study of CA-4948 as Monotherapy in Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS)Who this might be right forAcute Myelogenous LeukemiaMyelodysplastic Syndrome Curis, Inc. 366