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Results for “Relapsed/Refractory Multiple Sclerosis”

18 trials

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Showing 18 of 18 results

Large-scale testing (Phase 3)Study completedNCT01442233
What this trial is testing

Plasma Exchanges in Multiple Sclerosis (MS) Relapses

Who this might be right for
Multiple SclerosisMultiple Sclerosis, Acute Relapsing
University Hospital, Bordeaux 38
Early research (Phase 1)Looking for participantsNCT07361094
What this trial is testing

Autologous CD19/BCMA Dual-Target CAR-T for Relapsed/Refractory Autoimmune Diseases

Who this might be right for
Relapsed/Refractory Systemic Lupus ErythematosusRelapsed/Refractory Systemic SclerosisRelapsed/Refractory Idiopathic Inflammatory Myopathies+3 more
Beijing Boren Hospital 12
Early research (Phase 1)Active Not RecruitingNCT06220201
What this trial is testing

Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2)

Who this might be right for
Multiple SclerosisMyasthenia Gravis
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company 120
Very early researchLooking for participantsNCT04561557
What this trial is testing

Safety and Efficacy of CT103A Cells for Relapsed/Refractory Antibody-associated Inflammatory Diseases of the Nervous System

Who this might be right for
Autoimmune DiseasesAutoimmune Diseases of the Nervous SystemNeuromyelitis Optica Spectrum Disorder+7 more
Tongji Hospital 36
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07804004
What this trial is testing

A Safety and Efficacy Study Evaluating CTX112 in Subjects With Refractory Neurologic Autoimmune Disease

Who this might be right for
Progressive Multiple Sclerosis (PMS)Neuromyelitis OpticaMyelin Oligodendrocyte Glycoprotein Antibody-associated Disease+2 more
CRISPR Therapeutics 220
Early research (Phase 1)Looking for participantsNCT07224373
What this trial is testing

An Open-label Study of AZD0120 in Adults With Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
AstraZeneca 24
Very early researchLooking for participantsNCT07337785
What this trial is testing

CD19/BCMA-Targeted UCAR-T for Patients With Neurological Autoimmune Diseases

Who this might be right for
Relapsing or Refractory Multiple Sclerosis (MS)Myasthenia Gravis (MG)Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)+1 more
Tongji Hospital 36
Early research (Phase 1)Looking for participantsNCT07304154
What this trial is testing

A Study Evaluating the Safety and Efficacy of KITE-363 in Relapsed/Refractory Autoimmune Neurologic Diseases

Who this might be right for
Chronic Inflammatory Demyelinating PolyneuropathyMyasthenia GravisMultiple Sclerosis
Kite, A Gilead Company 52
Testing effectiveness (Phase 2)Ended earlyNCT00112723
What this trial is testing

Flavopiridol in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma

Who this might be right for
Adult Lymphocyte Depletion Hodgkin LymphomaAdult Lymphocyte Predominant Hodgkin LymphomaAdult Mixed Cellularity Hodgkin Lymphoma+25 more
National Cancer Institute (NCI) 46
Very early researchStudy completedNCT05080270
What this trial is testing

Feasibility Study of Tolerogenic Fibroblasts in Patients With Refractory Multiple Sclerosis

Who this might be right for
Multiple Sclerosis, Relapsing-RemittingMultiple Sclerosis
FibroBiologics 5
Very early researchNot Yet RecruitingNCT07583030
What this trial is testing

A Clinical Study to Evaluate LVIVO-TaVec400 for the Treatment of Relapsed/Refractory Autoimmune Diseases

Who this might be right for
Relapsed/Refractory Systemic Lupus Erythematosus (r/r SLE)Relapsed/Refractory IgG4-Related Disease (r/r IgG4-RD)Progressive Multiple Sclerosis (PMS)+1 more
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 44
Very early researchLooking for participantsNCT06939166
What this trial is testing

Universal Chimeric Antigen Receptor T-Cell （UCAR T-cell） Therapy Targeting CD19/B Cell Maturation Antigen （CD19/BCMA） in Patients With r/r Neurological Autoimmune Diseases

Who this might be right for
Neuromyelitis Optica Spectrum DisordersMyasthenia GravisMultiple Sclerosis+2 more
Tianjin Huanhu Hospital 12
Early research (Phase 1)Looking for participantsNCT07526493
What this trial is testing

Safety and Pharmacodynamics of QH103 Cell Injection in the Treatment of Patients With Relapsed/Refractory Antibody-Mediated Neurological Autoimmune Diseases.

Who this might be right for
Multiple Sclerosis (MS)Neuromyelitis Optica Spectrum Disorder (NMOSD)Autoimmune Encephalitis (AE)+4 more
Tongji Hospital 6
Very early researchNot Yet RecruitingNCT07748637
What this trial is testing

A Clinical Study to Evaluate the Safety and Efficacy of GT802 Injection in the Treatment of Relapsing/Refractory Multiple Sclerosis

Who this might be right for
Multiple Sclerosis (MS)
Daishi Tian 12
Very early researchNot Yet RecruitingNCT07392528
What this trial is testing

Universal Chimeric Antigen Receptor T-Cell （UCAR T-cell） Therapy Targeting CD19/ BCMA（QT-019C） in Patients With r/ r Neurological Autoimmune Diseases

Who this might be right for
Neuromyelitis Optica Spectrum DisordersMultiple SclerosisMyasthenia Gravis
Tianjin Huanhu Hospital 15
Not applicableStudy completedNCT04567264
What this trial is testing

Wireless, Implantable Tibial Nerve Stimulator System for the Treatment of Refractory Lower Urinary Tract Symptoms in Patients With Multiple Sclerosis

Who this might be right for
Multiple Sclerosis, Relapsing-Remitting
Chiara Zecca 23
Early research (Phase 1)WithdrawnNCT06869278
What this trial is testing

LCAR-AIO CAR-T Cells for Treating Relapsed/Refractory Neurological Autoimmune Diseases

Who this might be right for
Multiple Sclerosis (MS)Neuromyelitis Optica Spectrum Disease (NMOSD)Anti-Myelin Oligodendrocyte Glycoprotein-IgG Associated Disorders (MOGAD)+1 more
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07756268
What this trial is testing

Phase Ib/II Study of SYS6020 in Relapsing/Refractory Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
Tongji Hospital 25