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Results for “Relapsed/Refractory Pediatric B-ALL”

71 trials

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Showing 20 of 71 results

Early research (Phase 1)Temporarily pausedNCT00077493
What this trial is testing

BL22 Immunotoxin In Treating Young Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Non-Hodgkin's Lymphoma

Who this might be right for
LeukemiaLymphoma
MedImmune LLC 95
Testing effectiveness (Phase 2)Study completedNCT01700946
What this trial is testing

Therapy for Pediatric Relapsed or Refractory Precursor B-Cell Acute Lymphoblastic Leukemia and Lymphoma

Who this might be right for
Recurrent B-Cell Childhood Acute Lymphoblastic LeukemiaRecurrent Childhood B-Lymphoblastic Lymphoma
St. Jude Children's Research Hospital 80
Large-scale testing (Phase 3)Study completedNCT03123939
What this trial is testing

Phase III B in Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia
Novartis Pharmaceuticals 69
Not applicableLooking for participantsNCT06581081
What this trial is testing

Bridging Allogeneic Hematopoietic Stem Cell Transplantation or Not After CD19 CAR - T (S1904) Cell Therapy for r/r B-cell Acute Lymphoblastic Leukemia

Who this might be right for
Relapsed Adult ALLB-cell Acute Lymphoblastic LeukemiaRefractory Acute Lymphoblastic Leukemia+1 more
Peking University People's Hospital 130
Early research (Phase 1)Study completedNCT00363272
What this trial is testing

Ispinesib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Lymphoma

Who this might be right for
Childhood Burkitt LymphomaChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+22 more
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Looking for participantsNCT04544592
What this trial is testing

UCD19 CarT in Treatment of Pediatric B-ALL and B-NHL

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaB-cell Non Hodgkin Lymphoma
University of Colorado, Denver 45
Testing effectiveness (Phase 2)Study completedNCT03384654
What this trial is testing

Evaluate the Efficacy and Safety of Daratumumab in Pediatric and Young Adult Participants Greater Than or Equal to (>=)1 and Less Than or Equal to (<=) 30 Years of Age With Relapsed/Refractory Precursor B-cell or T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

Who this might be right for
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Janssen Research & Development, LLC 47
Testing effectiveness (Phase 2)Active Not RecruitingNCT02625480
What this trial is testing

Study Evaluating Brexucabtagene Autoleucel (KTE-X19) in Pediatric and Adolescent Participants With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia or Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma

Who this might be right for
Relapsed/Refractory B-precursor Acute Lymphoblastic LeukemiaRelapsed/Refractory B-Cell Non-Hodgkin Lymphoma
Kite, A Gilead Company 95
Not applicableLooking for participantsNCT06131801
What this trial is testing

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

Who this might be right for
Hematologic MalignancyLeukemiaLymphoma+16 more
Children's Hospital Medical Center, Cincinnati 30
Not applicableAvailableNCT03601442
What this trial is testing

CTL019 Out of Specification MAP for ALL or DLBCL Patients

Who this might be right for
Acute Lymphoblastic Leukemia (ALL)Diffuse Large B-cell Lymphoma (DLBCL)
Novartis Pharmaceuticals
Early research (Phase 1)UnknownNCT05727683
What this trial is testing

CD19-targeted CAR T Cells for Patients With Relapsed or Refractory in B-cell Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphocytic Leukemia
Shanghai Ming Ju Biotechnology Co., Ltd. 33
Testing effectiveness (Phase 2)Ended earlyNCT01483690
What this trial is testing

A Pilot Study of Decitabine and Vorinostat With Chemotherapy for Relapsed ALL

Who this might be right for
Acute Lymphoblastic LeukemiaPrecursor B-Cell Lymphoblastic LeukemiaPrecursor T-Cell Lymphoblastic Leukemia
Therapeutic Advances in Childhood Leukemia Consortium 23
Testing effectiveness (Phase 2)Looking for participantsNCT05366218
What this trial is testing

Tafasitamab (MOR00208) in Pediatric Patients With Relapsed or Refractory Acute B Lineage Leukemia

Who this might be right for
ALL, Childhood B-CellAcute Lymphoid Leukemia RelapseAcute Lymphocytic Leukemia Refractory
University Hospital Tuebingen 20
Testing effectiveness (Phase 2)WithdrawnNCT05740449
What this trial is testing

HEM-iSMART-A: Decitabine / Venetoclax and Navitoclax in Pediatric Patients With Relapsed or Refractory Hematological Malignancies

Who this might be right for
Acute Lymphoblastic Leukemia, in RelapseLymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) RecurrentLymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent+2 more
Princess Maxima Center for Pediatric Oncology
Testing effectiveness (Phase 2)Active Not RecruitingNCT05460533
What this trial is testing

A Second Infusion (Early Reinfusion) of Tisagenlecleucel in Children and Young Adults With B-Cell Acute Lymphoblastic Leukemia(B-ALL)

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
Memorial Sloan Kettering Cancer Center 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT03573700
What this trial is testing

Evaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of Relapsed/Refractory CD19+ Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia, in RelapseAcute Lymphoblastic Leukemia, Refractory
St. Jude Children's Research Hospital 24
Testing effectiveness (Phase 2)Looking for participantsNCT07134088
What this trial is testing

Subcutaneous Blinatumomab in Children With R/R and and MRD+ B-Cell Precursor Acute Lymphoblastic Leukemia

Who this might be right for
Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic LeukemiaMinimal Residual Disease + B-Cell Acute Lymphoblastic Leukemia
Amgen 104
Early research (Phase 1)Study completedNCT04888468
What this trial is testing

Phase I Study of pCAR-19B in the Treatment of CD19-positive Relapsed/Refractory B-ALL in Children and Adolescents

Who this might be right for
Acute Lymphoblastic LeukemiaRelapsed Pediatric ALLRefractory Acute Lymphoblastic Leukemia
Chongqing Precision Biotech Co., Ltd 9
Early research (Phase 1)Looking for participantsNCT05476770
What this trial is testing

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

Who this might be right for
Hematologic MalignancyAMLALL+8 more
Therapeutic Advances in Childhood Leukemia Consortium 54
Testing effectiveness (Phase 2)Ended earlyNCT03743246
What this trial is testing

Evaluate the Safety and Efficacy of JCAR017 in Pediatric Subjects With Relapsed/Refractory (r/r) B-cell Acute Lymphoblastic Leukemia (B-ALL) and B-cell Non-Hodgkin Lymphoma (B-NHL)

Who this might be right for
Precursor Cell Lymphoblastic Leukemia-LymphomaLymphoma, Non-Hodgkin
Celgene 21
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