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Results for “Relapsed/Refractory Pediatric B-ALL”

73 trials

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Showing 20 of 73 results

Testing effectiveness (Phase 2)Looking for participantsNCT05745714
What this trial is testing

HEM-iSMART-C: Ruxolitinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies

Who this might be right for
Acute Lymphoblastic Leukemia, in RelapseLymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) RecurrentLymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent+2 more
Princess Maxima Center for Pediatric Oncology 26
Early research (Phase 1)Ended earlyNCT00313053
What this trial is testing

Study of mAb 216 With Chemotherapy for Treatment of Pediatric Relapsed or Refractory B-progenitor Acute Lymphoblastic Leukemia

Who this might be right for
Leukemia, Lymphocytic, AcuteLeukemiaAcute Lymphoid Leukemia (ALL)
Clare Twist 4
Early research (Phase 1)Ended earlyNCT00100152
What this trial is testing

A Notch Signalling Pathway Inhibitor for Patients With T-cell Acute Lymphoblastic Leukemia/Lymphoma (ALL)(0752-013)

Who this might be right for
Leukemia, Lymphoblastic, Acute, T-cellMyelogenous LeukemiaChronic Lymphocytic Leukemia+1 more
Merck Sharp & Dohme LLC 50
Testing effectiveness (Phase 2)Looking for participantsNCT05334823
What this trial is testing

PCAR-19B in the Treatment of CD19-positive Relapsed/Refractory B-ALL in Children and Adolescents

Who this might be right for
Acute Lymphoblastic LeukemiaRelapsed Pediatric ALLRefractory Acute Lymphoblastic Leukemia
Chongqing Precision Biotech Co., Ltd 100
Testing effectiveness (Phase 2)Looking for participantsNCT04544592
What this trial is testing

UCD19 CarT in Treatment of Pediatric B-ALL and B-NHL

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaB-cell Non Hodgkin Lymphoma
University of Colorado, Denver 45
Testing effectiveness (Phase 2)UnknownNCT03467256
What this trial is testing

CD19 T-CAR for Treatment of Children and Young Adults With r/r B-ALL

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaAcute Lymphocytic Leukemia, Pediatric
Federal Research Institute of Pediatric Hematology, Oncology and Immunology 18
Early research (Phase 1)Study completedNCT00012181
What this trial is testing

Flavopiridol in Treating Children With Relapsed or Refractory Solid Tumors or Lymphomas

Who this might be right for
Recurrent Childhood Brain Stem GliomaRecurrent Childhood Cerebellar AstrocytomaRecurrent Childhood Cerebral Astrocytoma+19 more
National Cancer Institute (NCI) 30
Early research (Phase 1)Looking for participantsNCT06080191
What this trial is testing

Allogeneic Second-generation CD19-CAR T Cells for Pediatric Relapsed/Refractory B-ALL

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
Bambino Gesù Hospital and Research Institute 24
Testing effectiveness (Phase 2)Study completedNCT02435849
What this trial is testing

Study of Efficacy and Safety of CTL019 in Pediatric ALL Patients

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
Novartis Pharmaceuticals 80
Very early researchLooking for participantsNCT07695012
What this trial is testing

CAR-T Cell Therapy for ALL

Who this might be right for
Relapsed Acute Lymphoblastic Leukemia (ALL)
Dr. Zaineb Akram 10
Testing effectiveness (Phase 2)Ended earlyNCT05086315
What this trial is testing

First-in-human Study of SAR443579 Infusion in Male and Female Children and Adult Participants With Relapsed or Refractory Acute Myeloid Leukemia (R/R AML), B-cell Acute Lymphoblastic Leukemia (B-ALL), High Risk-myelodysplasia (HR-MDS), or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Who this might be right for
Acute Lymphocytic LeukaemiaAcute Myeloid Leukaemia RefractoryMyelodysplastic Syndromes+1 more
Sanofi 101
Testing effectiveness (Phase 2)Study completedNCT03389035
What this trial is testing

Transposon-manipulated Allogeneic CARCIK-CD19 Cells in Pediatric and Adult Patients With r/r ALL Post HSCT

Who this might be right for
Acute Lymphoblastic Leukemia, in Relapse
Fondazione Matilde Tettamanti Menotti De Marchi Onlus 21
Early research (Phase 1)Study completedNCT01231919
What this trial is testing

MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Leukemias of Ambiguous LineageAcute Myeloid Leukemia/Transient Myeloproliferative Disorder+48 more
National Cancer Institute (NCI) 45
Early research (Phase 1)Temporarily pausedNCT00077493
What this trial is testing

BL22 Immunotoxin In Treating Young Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Non-Hodgkin's Lymphoma

Who this might be right for
LeukemiaLymphoma
MedImmune LLC 95
Early research (Phase 1)Study completedNCT00053963
What this trial is testing

FR901228 in Treating Children With Refractory or Recurrent Solid Tumors or Leukemia

Who this might be right for
Blastic Phase Chronic Myelogenous LeukemiaChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+22 more
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Looking for participantsNCT05667506
What this trial is testing

CNCT19 Treatment in Children and Adolescent r/r ALL Patients(Pediatric)

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
Juventas Cell Therapy Ltd. 47
Early research (Phase 1)Ended earlyNCT01186328
What this trial is testing

EZN-3042 Administered With Re-induction Chemotherapy in Children With Relapsed Acute Lymphoblastic Leukemia (ALL)

Who this might be right for
Lymphoblastic Leukemia, AcuteLymphoblastic Leukemia, Acute, ChildhoodLeukemia, Lymphoblastic, Acute, T Cell+1 more
Therapeutic Advances in Childhood Leukemia Consortium 6
Very early researchNot Yet RecruitingNCT05779930
What this trial is testing

Safety and Feasibility of CD19 CAR T Cells Using CliniMACS Prodigy for Relapsed/Refractory CD19 Positive ALL and NHL

Who this might be right for
Acute Lymphoblastic Leukemia, in RelapseNon-Hodgkin's Lymphoma, RelapsedNon-Hodgkin's Lymphoma Refractory+3 more
Nationwide Children's Hospital 12
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07020260
What this trial is testing

The PACMAN-Hu19 Trial: a Study of the Safety and Feasibility of Locally Produced, CD19-targeted and Human CAR T-cell Therapy in Children and Young Adults With Relapsed or Refractory B-cell Malignancies

Who this might be right for
LeukemiaLymphoma
Princess Maxima Center for Pediatric Oncology 18
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07175415
What this trial is testing

HEM-iSMART E: Capivasertib + Venetoclax + Dexamethasone in Pediatric Patients With Relapsed or Refractory Hematological Malignancies

Who this might be right for
Acute Lymphoblastic LeukemiaLymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) RecurrentLymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory+2 more
Princess Maxima Center for Pediatric Oncology
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