Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Relapsed/Refractory Primary Central Nervous System Lymphoma”

130 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 130 results

Early research (Phase 1)WithdrawnNCT04500548
What this trial is testing

Testing the Combination of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) in Children, Adolescent, and Young Adult Patients With Relapsed/Refractory Cancers That Have an Increased Number of Genetic Changes, The 3CI Study

Who this might be right for
Constitutional Mismatch Repair Deficiency SyndromeHematopoietic and Lymphoid Cell NeoplasmLynch Syndrome+9 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Active Not RecruitingNCT05253118
What this trial is testing

Relapsed or Refractory Primary Diffuse Large B-cell Lymphoma (DLBCL) of the Central Nervous System (CNS)

Who this might be right for
DLBCL
Seoul National University Hospital 28
Early research (Phase 1)Enrolling By InvitationNCT06827782
What this trial is testing

Cord Blood-derived CAR-NK Cells Targeting CD19 for Refractory/Relapsed Central Nervous System Lymphoma

Who this might be right for
Refractory/Recurrent Central Nervous System Lymphoma
Second Affiliated Hospital, School of Medicine, Zhejiang University 42
Testing effectiveness (Phase 2)Study completedNCT03213678
What this trial is testing

Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Non-Hodgkin LymphomaAnn Arbor Stage IV Non-Hodgkin Lymphoma+30 more
National Cancer Institute (NCI) 18
Large-scale testing (Phase 3)UnknownNCT01316744
What this trial is testing

Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain

Who this might be right for
Cancer
University of Glasgow 214
Not applicableStudy completedNCT00956475
What this trial is testing

Quality of Life in Younger Leukemia and Lymphoma Survivors

Who this might be right for
Anxiety DisorderCancer SurvivorFatigue+7 more
Case Comprehensive Cancer Center 48
Not applicableLooking for participantsNCT00935090
What this trial is testing

3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer

Who this might be right for
Brain and Central Nervous System TumorsChronic Myeloproliferative DisordersLeukemia+6 more
Barbara Ann Karmanos Cancer Institute
Testing effectiveness (Phase 2)Active Not RecruitingNCT03038672
What this trial is testing

Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas

Who this might be right for
ALK-Positive Large B-Cell LymphomaDiffuse Large B-Cell Lymphoma Activated B-Cell TypeDiffuse Large B-Cell Lymphoma Associated With Chronic Inflammation+32 more
National Cancer Institute (NCI) 54
Early research (Phase 1)Study completedNCT01588015
What this trial is testing

Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Myeloid Leukemia in Remission+123 more
City of Hope Medical Center 36
Testing effectiveness (Phase 2)Study completedNCT03233204
What this trial is testing

Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Childhood Non-Hodgkin LymphomaAnn Arbor Stage IV Childhood Non-Hodgkin Lymphoma+33 more
National Cancer Institute (NCI) 6
Testing effectiveness (Phase 2)Study completedNCT02669511
What this trial is testing

PQR309 in Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma

Who this might be right for
Primary Central Nervous System Lymphoma
PIQUR Therapeutics AG 21
Early research (Phase 1)Study completedNCT01231919
What this trial is testing

MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Leukemias of Ambiguous LineageAcute Myeloid Leukemia/Transient Myeloproliferative Disorder+48 more
National Cancer Institute (NCI) 45
Testing effectiveness (Phase 2)Study completedNCT00066599
What this trial is testing

Voriconazole in Preventing Fungal Infections in Children With Neutropenia After Chemotherapy

Who this might be right for
Kidney CancerLeukemiaLymphoma+6 more
National Cancer Institute (NCI)
Not applicableLooking for participantsNCT07191431
What this trial is testing

A Clinical Study on the Efficacy and Safety of Methotrexate (MTX) or Thiotepa (for MTX Intolerance) or Temozolomide (TMZ) Combined With Orelabrutinib and Selinexor in Relapsed/Refractory Primary or Secondary Central Nervous System Lymphoma（SELINA）

Who this might be right for
Lymphoma Cns
Ruijin Hospital 25
Testing effectiveness (Phase 2)WithdrawnNCT03212807
What this trial is testing

Study Of Durvalumab and Lenalidomide In R/R EBV Associated DLBCL Subtypes, Primary CNS And Testicular DLBCL

Who this might be right for
EBV Related Non-Hodgkin's LymphomaPrimary CNS LymphomaPrimary Testicular Lymphoma
Singapore General Hospital
Testing effectiveness (Phase 2)Looking for participantsNCT06931652
What this trial is testing

Study of Epcoritamab in R/R Primary Diffuse Large B-cell Lymphoma of the CNS Treated With Lenalidomide and Rituximab

Who this might be right for
Primary CNS Lymphoma (PCNSL)
The Lymphoma Academic Research Organisation 60
Not applicableUnknownNCT04845139
What this trial is testing

A Case Study of Nivolumab for Relapsed/Refractory Primary Central Nervous System Lymphoma

Who this might be right for
Refractory Central Nervous System LymphomaRelapsed Primary Central Nervous System LymphomaPrimary Central Nervous System Lymphoma
Second Affiliated Hospital, School of Medicine, Zhejiang University 1
Large-scale testing (Phase 3)Study completedNCT00666211
What this trial is testing

Opioid Titration Order Sheet or Standard Care in Treating Patients With Cancer Pain

Who this might be right for
Brain and Central Nervous System TumorsChronic Myeloproliferative DisordersLeukemia+8 more
Vanderbilt-Ingram Cancer Center 98
Testing effectiveness (Phase 2)Study completedNCT00003406
What this trial is testing

Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Refractory Cancer

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+4 more
Cancer Treatment Centers of America 30
Early research (Phase 1)UnknownNCT00004036
What this trial is testing

Combination Chemotherapy Plus Amifostine in Treating Patients With Advanced Cancer

Who this might be right for
Chronic Myeloproliferative DisordersDrug/Agent Toxicity by Tissue/OrganLeukemia+5 more
The Cleveland Clinic 30
Load More Results