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Results for “Relapsed/Refractory Richter Transformation”

36 trials

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Showing 20 of 36 results

Testing effectiveness (Phase 2)Study completedNCT00304005
What this trial is testing

VNP40101M in Treating Patients With Richter Syndrome or Refractory or Relapsed Chronic Lymphocytic Leukemia or Other Lymphoproliferative Disorders

Who this might be right for
LeukemiaLymphoma
Vion Pharmaceuticals 35
Testing effectiveness (Phase 2)WithdrawnNCT02285244
What this trial is testing

Sotrastaurin Acetate in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Leukemia, Prolymphocytic Leukemia, or Richter's Transformation

Who this might be right for
Prolymphocytic LeukemiaRecurrent Mantle Cell LymphomaRecurrent Small Lymphocytic Lymphoma+2 more
James Blachly
Testing effectiveness (Phase 2)Ended earlyNCT06561425
What this trial is testing

A Study Evaluating the Safety and Efficacy of GLPG5101 (19CP02) in Participants With Non-Hodgkin Lymphoma

Who this might be right for
Relapsed/Refractory B-cell Non-Hodgkin LymphomaLymphomas Non-Hodgkin&Amp;Amp;#39;s B-Cell
Lakefront Biotherapeutics NV 130
Early research (Phase 1)Study completedNCT02535286
What this trial is testing

Study of Immunotherapy in Combination With Ublituximab and Umbralisib in Patients With Relapsed-refractory CLL or Richter's Transformation

Who this might be right for
Chronic Lymphocytic LeukemiaRichter Syndrome
TG Therapeutics, Inc. 27
Early research (Phase 1)Ended earlyNCT03778073
What this trial is testing

Study of Cosibelimab in Subjects With Relapsed or Refractory Lymphoma

Who this might be right for
B-cell Non Hodgkin LymphomaRichter's Transformation
TG Therapeutics, Inc. 18
Testing effectiveness (Phase 2)Study completedNCT02420912
What this trial is testing

Nivolumab and Ibrutinib in Treating Patients With Relapsed, Refractory, or High-Risk Untreated Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Richter Transformation

Who this might be right for
Loss of Chromosome 17pRecurrent Chronic Lymphocytic LeukemiaRecurrent Small Lymphocytic Lymphoma+3 more
M.D. Anderson Cancer Center 37
Testing effectiveness (Phase 2)Study completedNCT03010358
What this trial is testing

Entospletinib and Obinutuzumab in Treating Patients With Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Non-Hodgkin Lymphoma

Who this might be right for
AnemiaB-Cell Prolymphocytic LeukemiaGrade 1 Follicular Lymphoma+11 more
Alexey Danilov, MD 24
Early research (Phase 1)Ended earlyNCT04978779
What this trial is testing

Evaluate VIP152 in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia or Richter Syndrome

Who this might be right for
Relapsed Non Hodgkin LymphomaChronic Lymphocytic LeukemiaRefractory Chronic Lymphocytic Leukemia+4 more
Vincerx Pharma, Inc. 6
Early research (Phase 1)Study completedNCT05665530
What this trial is testing

PRT2527 as Monotherapy and in Combination With Zanubrutinib or Venetoclax in Participants With R/R Hematologic Malignancies

Who this might be right for
Aggressive B-Cell Non-Hodgkin's Lymphoma (NHL)Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)Mantle Cell Lymphoma (MCL)+9 more
Prelude Therapeutics Incorporated 86
Early research (Phase 1)Looking for participantsNCT07451054
What this trial is testing

CD45BE-HSPC + CART-45 Cells

Who this might be right for
B-Cell Non-Hodgkin Lymphoma (NHL)Richter's TransformationT-Cell Non-Hodgkin Lymphoma+1 more
University of Pennsylvania 42
Testing effectiveness (Phase 2)Study completedNCT02332980
What this trial is testing

Pembrolizumab Alone or With Idelalisib or Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Other Low-Grade B-Cell Non-Hodgkin Lymphomas

Who this might be right for
Recurrent B-Cell Non-Hodgkin LymphomaRecurrent Chronic Lymphocytic LeukemiaRecurrent Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue+20 more
Mayo Clinic 65
Testing effectiveness (Phase 2)Active Not RecruitingNCT03534323
What this trial is testing

Duvelisib and Venetoclax in Relapsed or Refractory CLL or SLL or RS

Who this might be right for
Chronic Lymphocytic LeukemiaRichter Syndrome
Dana-Farber Cancer Institute 55
Testing effectiveness (Phase 2)Looking for participantsNCT04792489
What this trial is testing

DALY II USA/ MB-CART2019.1 for DLBCL

Who this might be right for
Refractory Diffuse Large B Cell Lymphoma (DLBCL)Relapsed Diffuse Large B Cell LymphomaHigh Grade B-cell Lymphoma (HGBCL)+6 more
Miltenyi Biomedicine GmbH 315
Testing effectiveness (Phase 2)Ended earlyNCT05537766
What this trial is testing

Study of Brexucabtagene Autoleucel in Adults With Rare B-cell Malignancies

Who this might be right for
Relapsed/Refractory Waldenstrom MacroglobulinemiaRelapsed/Refractory Richter TransformationRelapsed/Refractory Burkitt Lymphoma+1 more
Kite, A Gilead Company 19
Early research (Phase 1)Active Not RecruitingNCT03479268
What this trial is testing

Pevonedistat and Ibrutinib in Treating Participants With Relapsed or Refractory CLL or Non-Hodgkin Lymphoma

Who this might be right for
B-Cell Prolymphocytic LeukemiaRecurrent Chronic Lymphocytic LeukemiaRecurrent Diffuse Large B-Cell Lymphoma+15 more
City of Hope Medical Center 18
Early research (Phase 1)Not Yet RecruitingNCT07539688
What this trial is testing

Phase I Clinical Study on the Safety and Efficacy of CY-219 CAR-T Cell Injection in the Treatment of Relapsed/Refractory B-Cell Lymphoma

Who this might be right for
Relapsed/Refractory B-cell LymphomaDiffuse Large B-cell LymphomaInert B-cell Lymphoma Transformed Into Large B-cell Lymphoma (Excluding Richter Transformation, THRLBCL, and BL)
Institute of Hematology & Blood Diseases Hospital, China 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT04623541
What this trial is testing

Safety and Efficacy Study of Epcoritamab in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter's Syndrome

Who this might be right for
Relapsed/Refractory Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaRichter's Syndrome+1 more
Genmab 194
Early research (Phase 1)Active Not RecruitingNCT03321643
What this trial is testing

Testing the Addition of an Immunotherapy Agent, Atezolizumab, When Given With the Usual Chemo-Immunotherapy Drug Combination (Rituximab Plus Gemcitabine and Oxaliplatin) for Relapsed/Refractory (That Has Come Back or Not Responded to Treatment) Transformed Diffuse Large B-Cell Lymphoma

Who this might be right for
Recurrent Diffuse Large B-Cell LymphomaRecurrent Transformed Non-Hodgkin LymphomaRefractory Diffuse Large B-Cell Lymphoma+3 more
National Cancer Institute (NCI)
Early research (Phase 1)WithdrawnNCT02238522
What this trial is testing

Phase 1 Study Evaluating ZEN003365 in Relapsed/Refractory Lymphoproliferative Malignancies or Relapsed/Refractory AML

Who this might be right for
Lymphoproliferative MalignanciesAcute Myeloid Leukemia
Zenith Epigenetics
Testing effectiveness (Phase 2)WithdrawnNCT02718755
What this trial is testing

Phase II Study of Fludarabine, Cytarabine (ARA-C) and Erwinase IV in Patients With Relapsed or Refractory Hematologic Malignancies

Who this might be right for
Hematologic Malignancy
M.D. Anderson Cancer Center
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