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Results for “Relapsed Mixed Phenotype Acute Leukemia”

54 trials

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Showing 20 of 54 results

Early research (Phase 1)WithdrawnNCT03807063
What this trial is testing

Rivogenlecleucel Donor Lymphocyte Immunotherapy in Treating Patients With Recurrent Blood Cancers After Stem Cell Transplant

Who this might be right for
Acute Bilineal LeukemiaMyelodysplastic/Myeloproliferative NeoplasmMyelodysplastic/Myeloproliferative Neoplasm, Unclassifiable+9 more
Fred Hutchinson Cancer Center
Early research (Phase 1)Study completedNCT05326516
What this trial is testing

Revumenib in Combination With Chemotherapy in Participants With R/R Acute Leukemia

Who this might be right for
Relapsed/Refractory LeukemiasAcute Lymphoblastic LeukemiaAcute Lymphocytic Leukemia+3 more
Syndax Pharmaceuticals 30
Early research (Phase 1)Looking for participantsNCT05292664
What this trial is testing

Venetoclax Basket Trial for High Risk Hematologic Malignancies

Who this might be right for
Myelodysplastic Syndromes, de NovoMyelodysplastic Syndromes, SecondaryMyelodysplastic Syndromes, Previously Treated+8 more
Andrew E. Place, MD 30
Early research (Phase 1)Looking for participantsNCT04872478
What this trial is testing

Pharmacokinetic and Safety Study of MRX-2843 in Adolescents and Adults With Relapsed/Refractory AML, ALL, or MPAL

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMixed Phenotype Acute Leukemia
Meryx, Inc. 50
Testing effectiveness (Phase 2)Study completedNCT04191187
What this trial is testing

Reduced Intensity Flu/Mel/TBI Conditioning for HAPLO HCT Patients With Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaBiphenotypic Acute Leukemia+15 more
H. Lee Moffitt Cancer Center and Research Institute 34
Testing effectiveness (Phase 2)Looking for participantsNCT03683433
What this trial is testing

Enasidenib and Azacitidine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia and IDH2 Gene Mutation

Who this might be right for
Acute Bilineal LeukemiaAcute Biphenotypic LeukemiaChronic Myelomonocytic Leukemia+4 more
M.D. Anderson Cancer Center 50
Early research (Phase 1)Active Not RecruitingNCT02879695
What this trial is testing

Blinatumomab and Nivolumab With or Without Ipilimumab in Treating Patients With Poor-Risk Relapsed or Refractory CD19+ Precursor B-Lymphoblastic Leukemia

Who this might be right for
Recurrent B Acute Lymphoblastic LeukemiaRecurrent Mixed Phenotype Acute LeukemiaRefractory B Acute Lymphoblastic Leukemia+1 more
National Cancer Institute (NCI) 28
Testing effectiveness (Phase 2)Looking for participantsNCT07356154
What this trial is testing

Revumenib and Mezigdomide in People With Leukemia

Who this might be right for
LeukemiaAcute LeukemiaRelapse Leukemia+5 more
Memorial Sloan Kettering Cancer Center 52
Early research (Phase 1)Looking for participantsNCT05476770
What this trial is testing

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

Who this might be right for
Hematologic MalignancyAMLALL+8 more
Therapeutic Advances in Childhood Leukemia Consortium 54
Testing effectiveness (Phase 2)Looking for participantsNCT04047641
What this trial is testing

Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaBlasts 20 Percent or More of Bone Marrow Nucleated CellsHigh Risk Myelodysplastic Syndrome+5 more
M.D. Anderson Cancer Center 80
Early research (Phase 1)Active Not RecruitingNCT03843528
What this trial is testing

Vorinostat Dose-escalation After Allogeneic Hematopoietic Cell Transplantation

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromesMixed Phenotype Acute Leukemia+1 more
Johns Hopkins All Children's Hospital 15
Testing effectiveness (Phase 2)Study completedNCT02044796
What this trial is testing

Filgrastim, Cladribine, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Newly Diagnosed or Relapsed/Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Who this might be right for
Acute Biphenotypic Leukemiade Novo Myelodysplastic SyndromePreviously Treated Myelodysplastic Syndrome+3 more
Fred Hutchinson Cancer Center 199
Testing effectiveness (Phase 2)Ended earlyNCT04501614
What this trial is testing

Ponatinib With Chemotherapy in Children, Teenagers, and Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Who this might be right for
Pediatric Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ALL)Ph+ Mixed Phenotype Acute Leukemia (MPAL)Philadelphia Chromosome-Like ALL (Ph-like ALL)
Takeda 11
Early research (Phase 1)Ended earlyNCT01887587
What this trial is testing

Vincristine, Doxorubicin, And Dexamethasone + Ixazomib in Acute Lymphoblastic Leukemia (ALL), Lymphoblastic Lymphoma Or Mixed Phenotype Acute Leukemia

Who this might be right for
Relapsed or Refractory Acute Lymphoblastic LeukemiaRelapsed or Refractory Lymphoblastic LymphomaMixed Phenotype Acute Leukemia
Ehab L Atallah 5
Testing effectiveness (Phase 2)Ended earlyNCT04874194
What this trial is testing

Omacetaxine and Venetoclax for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Harboring Mutant RUNX1

Who this might be right for
Hematopoietic and Lymphoid Cell NeoplasmRecurrent Acute Biphenotypic LeukemiaRecurrent Acute Myeloid Leukemia+4 more
M.D. Anderson Cancer Center 24
Early research (Phase 1)Looking for participantsNCT04375631
What this trial is testing

CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia

Who this might be right for
Recurrent Acute Myeloid LeukemiaRecurrent Chronic Myelomonocytic LeukemiaRecurrent Myelodysplastic Syndrome+6 more
Fred Hutchinson Cancer Center 120
Early research (Phase 1)Study completedNCT03194932
What this trial is testing

Study of Venetoclax in Combination With Chemotherapy in Pediatric Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Leukemia of Ambiguous Lineage

Who this might be right for
Acute Myeloid Leukemia
St. Jude Children's Research Hospital 62
Testing effectiveness (Phase 2)Looking for participantsNCT04797767
What this trial is testing

Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid Neoplasms

Who this might be right for
Acute Biphenotypic LeukemiaAcute Myeloid LeukemiaMixed Phenotype Acute Leukemia+10 more
University of Washington 62
Early research (Phase 1)Looking for participantsNCT03326921
What this trial is testing

HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant

Who this might be right for
Juvenile Myelomonocytic LeukemiaRecurrent Acute Biphenotypic LeukemiaRecurrent Acute Undifferentiated Leukemia+26 more
Fred Hutchinson Cancer Center 24
Testing effectiveness (Phase 2)WithdrawnNCT02718755
What this trial is testing

Phase II Study of Fludarabine, Cytarabine (ARA-C) and Erwinase IV in Patients With Relapsed or Refractory Hematologic Malignancies

Who this might be right for
Hematologic Malignancy
M.D. Anderson Cancer Center
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