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Results for “Relapsed or Refractory (r/r) B-cell Malignancies”

170 trials

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Showing 20 of 170 results

Large-scale testing (Phase 3)Looking for participantsNCT06006117
What this trial is testing

Mosunetuzumab-Lenalidomide Versus Investigator Choices in Patients With Relapsed or Refractory Marginal Zone Lymphoma

Who this might be right for
Marginal Zone Lymphoma
The Lymphoma Academic Research Organisation 260
Testing effectiveness (Phase 2)WithdrawnNCT00829205
What this trial is testing

Se-Methyl-Seleno-L-Cysteine, Rituximab, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Diffuse Large B-Cell Lymphoma That Has Relapsed or Not Responded to Treatment

Who this might be right for
Lymphoma
Cancer Research UK
Early research (Phase 1)Active Not RecruitingNCT05753501
What this trial is testing

Study to Evaluate Adverse Events, Change in Disease Activity, and How Oral ABBV-101 Moves Through the Body in Adult Participants With B-Cell Malignancies

Who this might be right for
Hematologic Cancer
AbbVie 135
Early research (Phase 1)Active Not RecruitingNCT01959698
What this trial is testing

Carfilzomib, Rituximab, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Stage I-IV Diffuse Large B-cell Lymphoma

Who this might be right for
CD20 PositiveRecurrent Diffuse Large B-Cell LymphomaRefractory Diffuse Large B-Cell Lymphoma+4 more
Roswell Park Cancer Institute 29
Early research (Phase 1)UnknownNCT04693676
What this trial is testing

C-CAR039 Treatment in Subjects With r/r NHL Subjects Non-Hodgkin's Lymphoma

Who this might be right for
Non-Hodgkin's B-cell Lymphoma
First Affiliated Hospital of Zhejiang University 17
Early research (Phase 1)Looking for participantsNCT06326008
What this trial is testing

Safety, Tolerability, and Pharmacokinetics of Donor-derived CD19 CAR Therapy Bridged Allo-HSCT and Sequential Donor-derived CD22 CAR Therapy for r/r B-ALL: a Clinical Trial

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaAcute Lymphoblastic Leukemia, in Relapse
Beijing GoBroad Hospital 48
Large-scale testing (Phase 3)Study completedNCT02763319
What this trial is testing

A Trial to Evaluate the Efficacy and Safety of Tafasitamab With Bendamustine (BEN) Versus Rituximab (RTX) With BEN in Adult Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Who this might be right for
Diffuse Large B-cell Lymphoma
Incyte Corporation 453
Testing effectiveness (Phase 2)Study completedNCT02226965
What this trial is testing

PNT2258 for Treatment of Patients With r/r DLBCL (Wolverine)

Who this might be right for
Lymphoma, Diffuse Large B-Cell
Sierra Oncology LLC - a GSK company 45
Testing effectiveness (Phase 2)WithdrawnNCT00845104
What this trial is testing

Fludarabine Phosphate, Rituximab, and Bevacizumab in Treating Patients With B-Cell Chronic Lymphocytic Leukemia That Has Relapsed or Not Responded To Treatment

Who this might be right for
B-cell Chronic Lymphocytic LeukemiaRefractory Chronic Lymphocytic Leukemia
Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium
Testing effectiveness (Phase 2)Ended earlyNCT04809467
What this trial is testing

A Study Evaluating Safety, PK, and Efficacy of Tafasitamab and Parsaclisib in Participants With Relapsed/Refractory Non Hodgkin Lymphoma (R/R NHL) or Chronic Lymphocytic Leukemia (CLL)

Who this might be right for
Chronic Lymphocytic LeukemiaNon Hodgkin Lymphoma
Incyte Corporation 54
Testing effectiveness (Phase 2)UnknownNCT03373019
What this trial is testing

Chidamide Combined With R-GDP in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Who this might be right for
ChidamideLymphoma, B-CellLymphoma, Large B-Cell, Diffuse+13 more
Fudan University 63
Early research (Phase 1)Ended earlyNCT05107856
What this trial is testing

PRT1419 as Monotherapy or in Combination With Azacitidine or Venetoclax in R/R Myeloid or B-cell Malignancies

Who this might be right for
Acute Myeloid LeukemiaB-cell Non-Hodgkin LymphomaChronic Lymphocytic Leukemia+7 more
Prelude Therapeutics Incorporated 21
Testing effectiveness (Phase 2)Looking for participantsNCT04502394
What this trial is testing

Safety and Efficacy of KRT-232 in Combination With Acalabrutinib in Subjects With R/R DLBCL or R/R CLL

Who this might be right for
Diffuse Large B Cell LymphomaChronic Lymphocytic LeukemiaNon Hodgkin Lymphoma
Kartos Therapeutics, Inc. 84
Large-scale testing (Phase 3)WithdrawnNCT00551239
What this trial is testing

Fludarabine and Rituximab With or Without Pixantrone in Treating Patients With Relapsed or Refractory Indolent Non-Hodgkin Lymphoma

Who this might be right for
LeukemiaLymphoma
CTI BioPharma
Not applicableNo Longer AvailableNCT04705454
What this trial is testing

Loncastixumab Tesirine (ADCT-402) Expanded Access Program (EAP) for Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Who this might be right for
Relapsed or Refractory Diffuse Large B-Cell Lymphoma (R/R DLBCL)
ADC Therapeutics S.A.
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07770698
What this trial is testing

Sonrotoclax (BGB-11417) in Children With Relapsed or Refractory Acute Myeloid Leukemia and B-cell Acute Lymphoblastic Leukemia

Who this might be right for
Relapsed Acute Myeloid LeukemiaRefractory Acute Myeloid LeukemiaB-cell Acute Lymphoblastic Leukemia+9 more
BeOne Medicines 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT04542824
What this trial is testing

Trial of the Safety and Efficacy of Epcoritamab in Japanese Subjects With Relapsed or Refractory (R/R) B-Cell Non-Hodgkin Lymphoma (R/R B-NHL)

Who this might be right for
Diffuse Large B Cell LymphomaHigh-grade B-cell LymphomaPrimary Mediastinal Large B Cell Lymphoma+3 more
Genmab 78
Early research (Phase 1)Active Not RecruitingNCT04447716
What this trial is testing

An Early Phase Study of Venetoclax, Lenalidomide, and Rituximab/Hyaluronidase in Slow-Growing Lymphomas That Have Come Back After Treatment or Have Not Responded to Treatment

Who this might be right for
Recurrent B-Cell Non-Hodgkin LymphomaRecurrent Follicular LymphomaRecurrent Indolent Adult Non-Hodgkin Lymphoma+5 more
Thomas Jefferson University 4
Testing effectiveness (Phase 2)Ended earlyNCT03135262
What this trial is testing

Obinutuzumab in Combination With Idasanutlin and Venetoclax in Participants With Relapsed or Refractory (R/R) Follicular Lymphoma (FL) or Rituximab in Combination With Idasanutlin and Venetoclax in Participants With R/R Diffuse Large B-Cell Lymphoma (DLBCL)

Who this might be right for
Follicular LymphomaLymphoma, Large B-Cell, Diffuse
Hoffmann-La Roche 29
Early research (Phase 1)Study completedNCT02741388
What this trial is testing

A Phase Ib Study of Oral Selinexor in Adult Patients With Relapsed/Refractory B-cell Lymphoma Receiving R-DHAOx or R-GDP

Who this might be right for
B-cell Lymphoma
The Lymphoma Academic Research Organisation 39
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