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Results for “Relapsed or Refractory (r/r) B-cell Malignancies”

166 trials

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Showing 20 of 166 results

Early research (Phase 1)WithdrawnNCT04094766
What this trial is testing

Safety and Efficacy of Dual Specificity CD19 and CD22 CAR-T Cell Immunotherapy in R/R Acute B Lymphoblastic Leukemia

Who this might be right for
Refractory B Acute Lymphoblastic LeukemiaRelapse B Acute Lymphoblastic Leukemia
Second Affiliated Hospital of Xi'an Jiaotong University
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07601607
What this trial is testing

Lisaftoclax Plus Chidamide and Rituximab in Relapsed or Refractory Diffuse Large B-cell Lymphoma

Who this might be right for
Relapsed or Refractory Diffuse Large B-Cell Lymphoma (R/R DLBCL)
Sun Yat-sen University 51
Early research (Phase 1)UnknownNCT03018093
What this trial is testing

A Phase I Study Evaluating Safety and Efficacy of C-CAR011 Treatment in Adult Subjects With r/r CD19+B-ALL

Who this might be right for
Relapsed or Refractory Acute Lymphoblastic Leukemia
Shanghai AbelZeta Ltd. 20
Early research (Phase 1)Ended earlyNCT04156828
What this trial is testing

Copanlisib and Combination Chemotherapy for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma or Relapsed Grade 3b Follicular Lymphoma

Who this might be right for
Grade 3b Follicular LymphomaRecurrent Diffuse Large B-Cell LymphomaRecurrent Follicular Lymphoma+2 more
University of Washington 12
Not applicableStudy completedNCT03751072
What this trial is testing

Efficacy and Toxicity of Blinatumomab in the French ATU for Adult BCP-ALL R/R, or With MRD+ (FRENCH-CYTO)

Who this might be right for
Acute Lymphoblastic Leukemia, in RelapseAcute Lymphoblastic Leukemia With Failed Remission
Group for Research in Adult Acute Lymphoblastic Leukemia 92
Testing effectiveness (Phase 2)Looking for participantsNCT05554939
What this trial is testing

Allogenic CD19-targeting CAR-γδT Cell Therapy in R/R NHL

Who this might be right for
Non Hodgkin's Lymphoma
Chinese PLA General Hospital 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT05222555
What this trial is testing

Safety and Pharmacokinetics Study of a Modified Tafasitamab IV Dosing Regimen Combined With Lenalidomide in R-R DLBCL Patients

Who this might be right for
Diffuse Large B Cell Lymphoma
Incyte Corporation 53
Testing effectiveness (Phase 2)Looking for participantsNCT06526793
What this trial is testing

Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL

Who this might be right for
B-cell Non-Hodgkin LymphomaFollicular Lymphoma (FL)Large B-Cell Lymphoma (LBCL)
AstraZeneca 240
Not applicableStudy completedNCT04150328
What this trial is testing

Lenalidomide Monotherapy in R/R DLBCL

Who this might be right for
Diffuse Large B Cell Lymphoma
MorphoSys AG 490
Early research (Phase 1)Looking for participantsNCT03666000
What this trial is testing

Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)

Who this might be right for
Non-Hodgkin LymphomaB-cell Acute Lymphoblastic LeukemiaChronic Lymphocytic Leukemia+1 more
Imugene Limited 135
Very early researchLooking for participantsNCT06976437
What this trial is testing

A Clinical Study of Allogeneic CD19/BCMA CAR-T Cells for the Treatment of R/R B-cell Malignant Tumors

Who this might be right for
B Cell LymphomaMultiple Myeloma
YANRU WANG 21
Testing effectiveness (Phase 2)Looking for participantsNCT06635330
What this trial is testing

Safety and Efficacy of CAR T Cell Therapy in Patients with R/r B-ALL

Who this might be right for
Relapse/Refractory B-cell Acute Lymphoblastic Leukemia
Kara Yakhteh Tajhiz Azma Company 5
Early research (Phase 1)Active Not RecruitingNCT05879744
What this trial is testing

CLN-978 in Patients With Relapsed or Refractory (R/R) B Cell Non-Hodgkin Lymphoma (B-NHL)

Who this might be right for
NHLNHL, Relapsed, Adult
Cullinan Therapeutics Inc. 90
Large-scale testing (Phase 3)Study completedNCT00078949
What this trial is testing

Chemotherapy Before Autologous Stem Cell Transplantation +/- Rituximab in Relapsed or Refractory Aggressive Non-Hodgkin's Lymphoma

Who this might be right for
Lymphoma
NCIC Clinical Trials Group 849
Large-scale testing (Phase 3)Active Not RecruitingNCT04680052
What this trial is testing

Assess Efficacy and Safety of Tafasitamab Plus Lenalidomide and Rituximab Compared to Placebo Plus Lenalidomide and Rituximab in Patients With Relapsed/Refractory (R/R) Follicular Lymphoma or Marginal Zone Lymphoma.

Who this might be right for
Follicular LymphomaMarginal Zone Lymphoma
Incyte Corporation 654
Early research (Phase 1)Study completedNCT03467373
What this trial is testing

Glofitamab in Combination With Rituximab or Obinutuzumab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP), or Polatuzumab Vedotin Plus Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone (CHP) in Participants With Non-Hodgkin Lymphomas or With DLBCL

Who this might be right for
B-Cell LymphomaNon-Hodgkin Lymphoma
Hoffmann-La Roche 111
Early research (Phase 1)Study completedNCT02219737
What this trial is testing

Ibrutinib and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma

Who this might be right for
CD20 PositiveRecurrent Diffuse Large B-Cell LymphomaRefractory Diffuse Large B-Cell Lymphoma
National Cancer Institute (NCI) 26
Not applicableNo Longer AvailableNCT04705454
What this trial is testing

Loncastixumab Tesirine (ADCT-402) Expanded Access Program (EAP) for Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Who this might be right for
Relapsed or Refractory Diffuse Large B-Cell Lymphoma (R/R DLBCL)
ADC Therapeutics S.A.
Early research (Phase 1)Active Not RecruitingNCT06285422
What this trial is testing

Study Evaluating SC262 in Subjects With r/r Non-Hodgkin's Lymphoma (VIVID)

Who this might be right for
Non Hodgkin's LymphomaLarge B-cell Lymphoma
Sana Biotechnology 6
Testing effectiveness (Phase 2)Study completedNCT03259529
What this trial is testing

Safety and Efficacy of Bendamustine, Gemcitabine, Rituximab, Nivolumab (BeGeRN) in Patients With r/r DLBCL

Who this might be right for
Diffuse Large B Cell Lymphoma
St. Petersburg State Pavlov Medical University 30
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