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Results for “Relapsed or Refractory B-cell Hematologic Malignancies”

713 trials

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Showing 20 of 713 results

Early research (Phase 1)Looking for participantsNCT06445803
What this trial is testing

CD19/CD22 CAR-T Cells in Adults With R/R ALL or NHL

Who this might be right for
Acute Lymphoblastic Leukemia, in RelapseAcute Lymphoblastic Leukemia With Failed RemissionB-cell Lymphoma Refractory+1 more
Rong Tao 48
Early research (Phase 1)Ended earlyNCT00098488
What this trial is testing

17-N-Allylamino-17-Demethoxygeldanamycin With or Without Rituximab in Treating Patients With Relapsed B-Cell Chronic Lymphocytic Leukemia or Prolymphocytic Leukemia

Who this might be right for
B-cell Chronic Lymphocytic LeukemiaProlymphocytic LeukemiaRefractory Chronic Lymphocytic Leukemia
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Study completedNCT00138164
What this trial is testing

Denileukin Diftitox in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Who this might be right for
Lymphoma
Jonsson Comprehensive Cancer Center 50
Testing effectiveness (Phase 2)WithdrawnNCT02420938
What this trial is testing

Urelumab (CD137 mAb) With Rituximab for Relapsed, Refractory or High-risk Untreated Chronic Lymphocytic Leukemia (CLL) Patients

Who this might be right for
Leukemia
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Active Not RecruitingNCT04205409
What this trial is testing

Nivolumab for Relapsed, Refractory, or Detectable Disease Post Chimeric Antigen Receptor T-cell Treatment in Patients With Hematologic Malignancies

Who this might be right for
Recurrent Chronic Lymphocytic LeukemiaRecurrent Diffuse Large B-Cell LymphomaRecurrent Follicular Lymphoma+15 more
University of Washington 20
Not applicableLooking for participantsNCT06961669
What this trial is testing

Intravenous Autologous CD19 CAR-T Cells for R/ R MM, B-ALL, and B-Cell Lymphoma

Who this might be right for
Lymphoblastic LeukemiaRelapsed or Refractory Multiple Myeloma (RRMM)
Anhui Provincial Hospital 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT01589302
What this trial is testing

PCI-32765 (Ibrutinib) in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or B-cell Prolymphocytic Leukemia

Who this might be right for
Prolymphocytic LeukemiaRecurrent Small Lymphocytic LymphomaRefractory/Relapsed Chronic Lymphocytic Leukemia
Kami Maddocks, MD 154
Early research (Phase 1)Active Not RecruitingNCT05665062
What this trial is testing

Autologous CD19 CAR-T Cell Therapy (SYNCAR-001) + Orthogonal IL-2 (STK-009) in Subjects With CD19+ Hematologic Malignancies

Who this might be right for
CLL/SLLNHLMantle Cell Lymphoma+4 more
Synthekine 36
Early research (Phase 1)Study completedNCT02049541
What this trial is testing

Study of BKM120 & Rituximab in Patients With Relapsed or Refractory Indolent B-Cell Lymphoma

Who this might be right for
Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid TissueNodal Marginal Zone B-cell LymphomaRecurrent Grade 1 Follicular Lymphoma+6 more
Kami Maddocks, MD 18
Early research (Phase 1)Study completedNCT02594384
What this trial is testing

A Phase I Dose Escalation Study of the Safety and Pharmacokinetics of LAM-002A In Patients With Non-Hodgkin's Lymphoma

Who this might be right for
Lymphoma, Non-Hodgkin; Leukemia, Chronic Lymphocytic
OrphAI Therapeutics 62
Testing effectiveness (Phase 2)Active Not RecruitingNCT02143414
What this trial is testing

Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaB Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1+2 more
National Cancer Institute (NCI) 53
Early research (Phase 1)Study completedNCT00046488
What this trial is testing

Safety and Efficacy of IDEC-152 in the Treatment of Chronic Lymphocytic Leukemia (CLL)

Who this might be right for
Chronic Lymphocytic Leukemia
Biogen 70
Testing effectiveness (Phase 2)Study completedNCT00436618
What this trial is testing

Everolimus in Treating Patients With Lymphoma That Has Relapsed or Not Responded to Previous Treatment

Who this might be right for
LeukemiaLymphomaLymphoproliferative Disorder
Mayo Clinic 277
Testing effectiveness (Phase 2)Study completedNCT00047021
What this trial is testing

Combination Chemotherapy in Treating Patients With Recurrent or Refractory Leukemia or Lymphoma

Who this might be right for
LeukemiaLymphoma
Case Comprehensive Cancer Center 3
Early research (Phase 1)Study completedNCT00621452
What this trial is testing

Genetically Engineered Lymphocytes, Cyclophosphamide, and Aldesleukin in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma or Indolent B-Cell Non-Hodgkin Lymphoma

Who this might be right for
B-cell Chronic Lymphocytic LeukemiaExtranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid TissueNodal Marginal Zone B-cell Lymphoma+8 more
Fred Hutchinson Cancer Center 12
Early research (Phase 1)Study completedNCT00161187
What this trial is testing

Irradiated Donor Lymphocyte Infusion in Treating Patients With Relapsed or Refractory Hematologic Cancer or Solid Tumor

Who this might be right for
Cancer
University of Medicine and Dentistry of New Jersey 37
Early research (Phase 1)Study completedNCT01300026
What this trial is testing

AMG 319 Lymphoid Malignancy FIH

Who this might be right for
CancerChronic Lymphocytic LeukemiaDiffuse Large Cell Lymphoma+11 more
Amgen 28
Early research (Phase 1)UnknownNCT04154709
What this trial is testing

CTA101 UCAR-T Cell Injection for Treatment of Relapsed or Refractory CD19+ B-cell Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia
Kai Lin Xu; Jun Nian Zheng 15
Very early researchUnknownNCT04156178
What this trial is testing

CD20-CD19 Compound CAR (cCAR) T Cells for Patients With Relapsed /Refractory B Cell Malignancies

Who this might be right for
B Cell LymphomaB Cell Leukemia
iCell Gene Therapeutics 12
Early research (Phase 1)Study completedNCT01290549
What this trial is testing

Escalating Doses of Polatuzumab Vedotin in Participants With Relapsed or Refractory B-Cell Non-Hodgkins Lymphoma and Chronic Lymphocytic Leukemia and Polatuzumab Vedotin in Combination With Rituximab in Participants With Relapsed or Refractory B-Cell Non-Hodgkins Lymphoma

Who this might be right for
Non-Hodgkins LymphomaChronic Lymphocytic Leukemia
Genentech, Inc. 95
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