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Results for “Relapsed or Refractory Pediatric Tumor”

188 trials

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Showing 20 of 188 results

Not applicableStudy completedNCT04213209
What this trial is testing

Special Drug Use Surveillance for Brentuximab Vedotin Intravenous Infusion "Relapsed or Refractory CD30-positive Peripheral T Cell Lymphoma or Pediatric Hodgkin Lymphoma"

Who this might be right for
Peripheral T Cell LymphomaPediatric Hodgkin Lymphoma
Takeda 95
Not applicableLooking for participantsNCT06866873
What this trial is testing

CD-19 CAR-T Cell for Pediatric ALL or Lymphoma

Who this might be right for
Lymphoma, B-CellAcute Lymphoblastic Leukemia, Pediatric
Hong Kong Children's Hospital 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT04571138
What this trial is testing

A Pediatric and Young Adult Trial of Genetically Modified T Cells Directed Against CD22 for Relapsed/Refractory Leukemia or Lymphoma

Who this might be right for
LeukemiaLymphoma
Seattle Children's Hospital 42
Early research (Phase 1)Study completedNCT00079404
What this trial is testing

17-N-Allylamino-17-Demethoxygeldanamycin in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia

Who this might be right for
Acute Undifferentiated LeukemiaRecurrent Childhood Acute Lymphoblastic LeukemiaRecurrent Childhood Acute Myeloid Leukemia+2 more
National Cancer Institute (NCI) 36
Testing effectiveness (Phase 2)Ended earlyNCT00866281
What this trial is testing

The Safety and Preliminary Efficacy of Oral Midostaurin (PKC412) in Relapsed or Refractory Pediatric Leukemia

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic Leukemia
Novartis Pharmaceuticals 22
Early research (Phase 1)Study completedNCT01231919
What this trial is testing

MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Leukemias of Ambiguous LineageAcute Myeloid Leukemia/Transient Myeloproliferative Disorder+48 more
National Cancer Institute (NCI) 45
Early research (Phase 1)Study completedNCT01411267
What this trial is testing

AC220 for Children With Relapsed/Refractory ALL or AML

Who this might be right for
Lymphoblastic Leukemia, Acute, ChildhoodMyelogenous Leukemia, Acute, Childhood
Therapeutic Advances in Childhood Leukemia Consortium 24
Early research (Phase 1)Looking for participantsNCT06173518
What this trial is testing

CD19 Targeted CAR T Cell Therapy in Pediatric Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia (B ALL) and Aggressive Mature B-cell Non-Hodgkin Lymphoma (B NHL)

Who this might be right for
Relapsed or Refractory B Cell Acute Lymphoblastic LeukemiaRelapsed or Refractory B Cell Non-Hodgkin Lymphoma
Autolus Limited 30
Early research (Phase 1)Study completedNCT04996160
What this trial is testing

Palbociclib in Combo w/Chemotherapy in Peds Relapsed/Refractory Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia, PediatricRelapsed Acute Lymphoblastic LeukemiaRefractory Acute Lymphoblastic Leukemia
Tanja Andrea Gruber 2
Testing effectiveness (Phase 2)Looking for participantsNCT06316960
What this trial is testing

Safety and Efficacy of Avapritinib in Relapsed or Refractory Pediatric CBF-AML With KIT Mutation

Who this might be right for
AML, ChildhoodRelapse/RecurrenceRefractory AML+2 more
Children's Hospital of Soochow University 50
Testing effectiveness (Phase 2)Looking for participantsNCT06635330
What this trial is testing

Safety and Efficacy of CAR T Cell Therapy in Patients with R/r B-ALL

Who this might be right for
Relapse/Refractory B-cell Acute Lymphoblastic Leukemia
Kara Yakhteh Tajhiz Azma Company 5
Testing effectiveness (Phase 2)Active Not RecruitingNCT03573700
What this trial is testing

Evaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of Relapsed/Refractory CD19+ Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia, in RelapseAcute Lymphoblastic Leukemia, Refractory
St. Jude Children's Research Hospital 24
Early research (Phase 1)Study completedNCT00002912
What this trial is testing

Combination Chemotherapy Plus PSC-833 in Treating Children With Refractory or Relapsed Acute Leukemia

Who this might be right for
Leukemia
National Cancer Institute (NCI) 3
Early research (Phase 1)Study completedNCT00053963
What this trial is testing

FR901228 in Treating Children With Refractory or Recurrent Solid Tumors or Leukemia

Who this might be right for
Blastic Phase Chronic Myelogenous LeukemiaChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+22 more
National Cancer Institute (NCI) 30
Not applicableStudy completedNCT02613962
What this trial is testing

Proof -of -Concept Study To Stratify Targeted Therapies Adapted To Molecular Profiling

Who this might be right for
Relapsed or Refractory Pediatric Tumor
Gustave Roussy, Cancer Campus, Grand Paris 791
Early research (Phase 1)Study completedNCT02601937
What this trial is testing

EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma

Who this might be right for
Rhabdoid TumorsINI1-negative TumorsSynovial Sarcoma+1 more
Epizyme, Inc. 109
Early research (Phase 1)Study completedNCT03236857
What this trial is testing

The Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies

Who this might be right for
MalignanciesAcute Lymphoblastic Leukemia (ALL)Acute Myeloid Leukemia (AML)+2 more
AbbVie 143
Testing effectiveness (Phase 2)Looking for participantsNCT04634357
What this trial is testing

ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma

Who this might be right for
HepatoblastomaHepatocellular Carcinoma (HCC)Liver Neoplasms+3 more
Eureka Therapeutics Inc. 15
Testing effectiveness (Phase 2)WithdrawnNCT04156659
What this trial is testing

Study of Tisagenlecleucel in Chinese Pediatric and Young Adult Subjects With Relapsed or Refractory B-cell ALL

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
Novartis Pharmaceuticals
Testing effectiveness (Phase 2)Study completedNCT03213691
What this trial is testing

Selumetinib Sulfate in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Childhood Non-Hodgkin LymphomaAnn Arbor Stage IV Childhood Non-Hodgkin Lymphoma+8 more
National Cancer Institute (NCI) 21
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