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Results for “Renal Hypoxia”

69 trials

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Showing 20 of 69 results

Early research (Phase 1)Study completedNCT04846920
What this trial is testing

Belzutifan (MK-6482) in Participants With Advanced Clear Cell Renal Cell Carcinoma (MK-6482-018)

Who this might be right for
Carcinoma, Renal Cell
Merck Sharp & Dohme LLC 29
Testing effectiveness (Phase 2)Active Not RecruitingNCT03634540
What this trial is testing

A Trial of Belzutifan (PT2977, MK-6482) in Combination With Cabozantinib in Patients With Clear Cell Renal Cell Carcinoma (ccRCC) (MK-6482-003)

Who this might be right for
Renal Cell Carcinoma (RCC)Clear Cell Renal Cell Carcinoma (ccRCC)Kidney Cancer+6 more
Peloton Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 118
Early research (Phase 1)WithdrawnNCT05295784
What this trial is testing

PK and Safety of Caffeine in Neonates With Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia

Who this might be right for
Acute Kidney InjuryHypoxic-Ischemic EncephalopathyCaffeine
University of Arkansas
Early research (Phase 1)Study completedNCT01497444
What this trial is testing

Sorafenib Tosylate and Hypoxia-Activated Prodrug TH-302 in Treating Patients With Advanced Kidney Cancer or Liver Cancer That Cannot Be Removed By Surgery

Who this might be right for
Kidney CancerLiver Cancer
Alliance for Clinical Trials in Oncology 24
Not applicableUnknownNCT03897920
What this trial is testing

Doppler Ultrasound Renal Arterial Resistive Indices As Predictor Of Multiorgan Failure In Patients With Acute Hypoxic Respiratory Failure Admitted To Respiratory Intensive Care Unit (Cryptic Shock Index- RICU)

Who this might be right for
Respiratory FailureMulti Organ Failure
University of Modena and Reggio Emilia 30
Early research (Phase 1)Study completedNCT02327546
What this trial is testing

Effects of Ferrous Sulfate on the Pharmacokinetics of AKB-6548

Who this might be right for
Healthy Volunteers
Akebia Therapeutics 10
Not applicableNot Yet RecruitingNCT07180875
What this trial is testing

"Hypoxic vs. Aerobic Training in Chronic Kidney Disease

Who this might be right for
Chronic Kidney Disease (CKD), Stages 3-4 Exercise Tolerance / Functional Capacity Vascular Health / Arterial Stiffness Fatigue in CKD
Pharos University in Alexandria 60
Testing effectiveness (Phase 2)Study completedNCT02260193
What this trial is testing

16-Week Repeat Oral Dose Study of AKB-6548 for Anemia in Participants With End Stage Renal Disease (ESRD) Requiring Chronic Hemodialysis

Who this might be right for
AnemiaEnd Stage Renal Disease
Akebia Therapeutics 94
Large-scale testing (Phase 3)Active Not RecruitingNCT05899049
What this trial is testing

Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, vs Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)-China Extension Study

Who this might be right for
Carcinoma, Renal Cell
Merck Sharp & Dohme LLC 251
Early research (Phase 1)Study completedNCT00588276
What this trial is testing

Pilot Evaluation of 124I-Iodo-Azomycin Galacto-Pyranoside (*IAZGP) Positron Emission Tomography (PET) in the Imaging of Hypoxic Tumors

Who this might be right for
Cervical CancerHEENT CancerRenal Cancer+3 more
Memorial Sloan Kettering Cancer Center 15
Not applicableStudy completedNCT03433079
What this trial is testing

Acute Kidney Injury in Severe Trauma

Who this might be right for
Acute Kidney Injury
University Hospital Ostrava 81
Large-scale testing (Phase 3)Active Not RecruitingNCT05239728
What this trial is testing

Belzutifan (MK-6482) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Clear Cell Renal Cell Carcinoma Post Nephrectomy (MK-6482-022)

Who this might be right for
Carcinoma, Renal Cell
Merck Sharp & Dohme LLC 1,800
Early research (Phase 1)Active Not RecruitingNCT07000149
What this trial is testing

Investigate the Efficacy and Safety of Volrustomig ± Casdatifan vs Nivolumab + Ipilimumab as 1L Treatment for Advanced ccRCC

Who this might be right for
Advanced Clear Cell Renal Cell Carcinoma
AstraZeneca 9
Post-approval studies (Phase 4)Study completedNCT04193566
What this trial is testing

Acute Effects of SGLT2 Inhibition on Renal Oxygenation and Autonomic Function in Type 1 Diabetes

Who this might be right for
NephropathyHypoxiaMitochondrial Alteration+2 more
Steno Diabetes Center Copenhagen 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05810311
What this trial is testing

The Effect of Roxadustat on Renal Oxygenation in Diabetes Nephropathy

Who this might be right for
Diabetes ComplicationsDiabetes; Nephropathy (Manifestation)
Region Stockholm 30
Post-approval studies (Phase 4)Study completedNCT04027530
What this trial is testing

Renal Oxygenation, Oxygen Consumption and Hemodynamic Kinetics in Type 2 DIabetes: an Ertugliflozin Study.

Who this might be right for
Type 2 Diabetes MellitusDiabetic Kidney DiseaseDiabetic Nephropathy+4 more
Amsterdam UMC, location VUmc 40
Not applicableStudy completedNCT07743099
What this trial is testing

Renal and Cerebral NIRS and Early Acute Kidney Injury in Cooled Neonates With Birth Asphyxia

Who this might be right for
Hypoxic-Ischemic EncephalopathyAcute Kidney InjuryHypoxic-Ischemic Encephalopathy, Neonatal+1 more
Agah Bahadır Öztürk,MD 46
Not applicableStudy completedNCT05430724
What this trial is testing

The Effects of Nicardipine and Esmolol Applied for Controlled Hypotension

Who this might be right for
HypotensionSurgery-ComplicationsOxygen Deficiency
Yuzuncu Yil University 80
Large-scale testing (Phase 3)WithdrawnNCT03242967
What this trial is testing

Study to Evaluate Three Times Per Week (TIW) Oral Dosing of Vadadustat for Anemia in Subjects With Dialysis-Dependent Chronic Kidney Disease (DD-CKD)

Who this might be right for
AnemiaDialysis-Dependent Chronic Kidney Disease
Akebia Therapeutics
Very early researchStudy completedNCT00884520
What this trial is testing

An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037

Who this might be right for
Lung CancerSquamous Cell CarcinomaHead and Neck Cancer+2 more
Siemens Molecular Imaging 16
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