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Results for “Resistant Solid Malignancies”

246 trials

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Showing 20 of 246 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07681297
What this trial is testing

Tislelizumab in Combination With Bevacizumab and Capecitabine in Advanced Solid Tumors With Evaluation in Immunotherapy-Resistant and Central Nervous System Disease

Who this might be right for
Advanced Solid Tumor CancerTriple-Negative Breast Cancer (TNBC)CNS Disease+1 more
National University Hospital, Singapore 154
Early research (Phase 1)Looking for participantsNCT07514065
What this trial is testing

TSL2109 Capsules in Advanced Solid Tumor Patients: Safety, Tolerability, PK and Preliminary Efficacy

Who this might be right for
Metastatic Castration-Resistant Prostate Cancer Patients
Tasly Pharmaceutical Group Co., Ltd 78
Not applicableLooking for participantsNCT01050504
What this trial is testing

Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer

Who this might be right for
Localized Renal Pelvis and Ureter Urothelial CarcinomaMalignant Solid NeoplasmMetastatic Malignant Neoplasm in the Bone+8 more
University of Washington 1,500
Testing effectiveness (Phase 2)Ended earlyNCT04171700
What this trial is testing

Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes

Who this might be right for
Solid Tumor
pharmaand GmbH 83
Early research (Phase 1)Study completedNCT04252339
What this trial is testing

RLY-1971 in Subjects With Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Tumor, Unspecified, Adult
Hoffmann-La Roche 56
Testing effectiveness (Phase 2)Looking for participantsNCT07288359
What this trial is testing

Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors

Who this might be right for
Advanced HR+/HER2- Breast CancerAdvanced CCNE1-amplified Solid TumorsMetastatic Castration-resistant Prostate Cancer
Novartis Pharmaceuticals 205
Testing effectiveness (Phase 2)Ended earlyNCT03681951
What this trial is testing

First-time-in-human (FTIH) Study of GSK3145095 Alone and in Combination With Other Anticancer Agents in Adults With Advanced Solid Tumors

Who this might be right for
Neoplasms, Pancreatic
GlaxoSmithKline 8
Testing effectiveness (Phase 2)UnknownNCT04640246
What this trial is testing

Study of TBX-3400 in Subjects With Solid Malignant Tumors Resistant or Refractory to Standard Therapies

Who this might be right for
CancerTumor, SolidRefractory Cancer
Taiga Biotechnologies, Inc. 60
Very early researchLooking for participantsNCT05141474
What this trial is testing

Assessment of the Safety and Tolerability of ex Vivo Next-generation Neoantigen-selected Tumor-infiltrating Lymphocyte (TIL) Therapy in Advanced Epithelial Tumors and Immune Checkpoint Blockade (ICB) Resistant Solid Tumors

Who this might be right for
Epithelial Tumors, MalignantMalignant Solid Tumor
Vall d'Hebron Institute of Oncology 10
Early research (Phase 1)Ended earlyNCT03799003
What this trial is testing

ASP1951 in Subjects With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Astellas Pharma Global Development, Inc. 119
Early research (Phase 1)Ended earlyNCT05047536
What this trial is testing

KZR-261 in Subjects With Advanced Solid Malignancies

Who this might be right for
Advanced/Metastatic Solid Tumor
Kezar Life Sciences, Inc. 61
Early research (Phase 1)UnknownNCT05415098
What this trial is testing

Study of Safety, Pharmacokinetic and Efficacy of APG-5918 in Advanced Solid Tumors or Lymphomas

Who this might be right for
Nasopharyngeal CarcinomaCastrate Resistant Prostate CancerGastric Cancer+6 more
Ascentage Pharma Group Inc. 90
Early research (Phase 1)Ended earlyNCT06264921
What this trial is testing

A Study With NKT3447 for Adults With Advanced/Metastatic Solid Tumors

Who this might be right for
Solid TumorSolid Tumor, AdultAdvanced Solid Tumor+26 more
NiKang Therapeutics, Inc. 23
Not applicableLooking for participantsNCT07737509
What this trial is testing

Understanding the Genetic and Biological Factors That Influence Cancer Treatment Response and Resistance in Patients With Advanced Solid Tumours Through Sample Analysis

Who this might be right for
Advanced Solid Tumours
Institute of Cancer Research, United Kingdom 5,000
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06724263
What this trial is testing

A Multicenter, Open-label Phase IIa Clinical Study to Evaluate the Efficacy and Safety of B1962 Injection in the Treatment of Advanced Malignant Solid Tumors

Who this might be right for
Recurrent Platinum-resistant Epithelial Ovarian CancerTriple Negative Breast Cancer (TNBC)Cervical Cancers+4 more
Tasly Biopharmaceuticals Co., Ltd. 120
Early research (Phase 1)Study completedNCT03295084
What this trial is testing

Safety, Tolerability and Pharmacokinetics of Oral Tablet of Irinotecan in Adult Patients With Solid Tumors

Who this might be right for
Metastatic Colorectal Cancer
Dorte Nielsen 39
Testing effectiveness (Phase 2)Ended earlyNCT05256381
What this trial is testing

SOT101 in Combination With Pembrolizumab to Evaluate the Efficacy and Safety in Patients With Selected Advanced Solid Tumors

Who this might be right for
Non-Small Cell Lung CancerColorectal CancerCutaneous Squamous Cell Carcinoma+3 more
SOTIO Biotech AG 166
Early research (Phase 1)Ended earlyNCT05274451
What this trial is testing

Investigate LYL797 in Adults With Solid Tumors

Who this might be right for
Triple Negative Breast CancerTNBC - Triple-Negative Breast CancerNon-small Cell Lung Cancer+20 more
Lyell Immunopharma, Inc. 57
Testing effectiveness (Phase 2)Ended earlyNCT03330405
What this trial is testing

Javelin Parp Medley: Avelumab Plus Talazoparib In Locally Advanced Or Metastatic Solid Tumors

Who this might be right for
Avelumab in Combination With Talazoparib Will be Investigated in Patients With Locally Advanced (Primary or Recurrent) or Metastatic Solid Tumors
Pfizer 223
Early research (Phase 1)Active Not RecruitingNCT04616534
What this trial is testing

Testing the Addition of an Anti-cancer Drug, Elimusertib (BAY 1895344) ATR Inhibitor, to the Chemotherapy Treatment (Gemcitabine) for Advanced Pancreatic and Ovarian Cancer, and Advanced Solid Tumors

Who this might be right for
Advanced Fallopian Tube CarcinomaAdvanced Malignant Solid NeoplasmAdvanced Ovarian Carcinoma+19 more
National Cancer Institute (NCI) 14
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