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Results for “Resistant Solid Malignancies”

235 trials

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Showing 20 of 235 results

Testing effectiveness (Phase 2)WithdrawnNCT05582031
What this trial is testing

Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancers

Who this might be right for
Anal Squamous Cell CarcinomaColorectal NeoplasmsSoft Tissue Sarcoma+5 more
Translational Research in Oncology
Early research (Phase 1)Looking for participantsNCT06784193
What this trial is testing

Phase 1 Study of OP-3136 in Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic ER+ HER2- Breast Cancer (mBC)Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)Advanced or Metastatic Castration-Resistant Prostate Cancer (mCRPC)+3 more
Olema Pharmaceuticals, Inc. 180
Early research (Phase 1)Study completedNCT01497925
What this trial is testing

Ph 1 Trial of ADI-PEG 20 Plus Docetaxel in Solid Tumors With Emphasis on Prostate Cancer and Non-Small Cell Lung Cancer

Who this might be right for
Solid TumorsProstate Cancer
Polaris Group 43
Testing effectiveness (Phase 2)Looking for participantsNCT05786924
What this trial is testing

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

Who this might be right for
Non-small Cell Lung CancerHistiocytic NeoplasmHistiocytosis+29 more
Institut de Recherches Internationales Servier 554
Early research (Phase 1)Study completedNCT04925284
What this trial is testing

Study of XB002 in Subjects With Solid Tumors (JEWEL-101)

Who this might be right for
Non Small Cell Lung CancerCervical CancerSCCHN+8 more
Exelixis 269
Testing effectiveness (Phase 2)Ended earlyNCT04052204
What this trial is testing

Avelumab With Bempegaldesleukin With or Without Talazoparib or Enzalutamide in Advanced or Metastatic Solid Tumors

Who this might be right for
Squamous Cell Carcinoma of the Head and Neck (SCCHN)Metastatic Castration Resistant Prostate Cancer (mCRPC)
Pfizer 3
Early research (Phase 1)Study completedNCT00121719
What this trial is testing

An Open Label Dose Escalation Study Of E7080

Who this might be right for
Solid Tumor or Lymphoma
Eisai Inc. 82
Very early researchNot Yet RecruitingNCT07052760
What this trial is testing

Imaging of Solid Tumors Using DLL3 SPECT

Who this might be right for
Solid Tumor CancerCastration Resistant Prostate CancerCastration Resistant Prostate Cancer (CRPC)+1 more
Thomas Hope 45
Early research (Phase 1)Looking for participantsNCT06242470
What this trial is testing

MGC026 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorAdvanced CancerMetastatic Cancer+19 more
MacroGenics 250
Early research (Phase 1)UnknownNCT04839991
What this trial is testing

Study of CB307 in Patients With Advanced and/or Metastatic PSMA-positive Tumours.

Who this might be right for
Advanced and/or Metastatic Solid Tumours
Crescendo Biologics Ltd. 70
Testing effectiveness (Phase 2)Active Not RecruitingNCT06076135
What this trial is testing

Intestinal Low Dose Radiotherapy Combined With Immunotherapy in Immune-resistant Metastatic Solid Tumors

Who this might be right for
Metastatic Malignant Solid NeoplasmRadiotherapyImmune Checkpoint Blockade+1 more
Chuangzhen Chen 16
Testing effectiveness (Phase 2)Looking for participantsNCT07192120
What this trial is testing

MHB048C in Patients With Advanced Solid Tumors

Who this might be right for
mCRPC (Metastatic Castration-resistant Prostate Cancer)Advanced Malignant Solid Tumor
Minghui Pharmaceutical (Hangzhou) Ltd 200
Testing effectiveness (Phase 2)Ended earlyNCT04504916
What this trial is testing

Zilovertamab Vedotin (MK-2140/VLS-101) in Participants With Solid Tumors (MK-2140-002)

Who this might be right for
Triple-negative Breast CancerNon-squamous Non-small-cell Lung CancerNSCLC+12 more
VelosBio Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 102
Testing effectiveness (Phase 2)Study completedNCT04068896
What this trial is testing

Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy

Who this might be right for
Pancreatic CancerMetastatic Castration-resistant Prostate CancerBladder Cancer+8 more
NGM Biopharmaceuticals, Inc 89
Early research (Phase 1)Study completedNCT01540526
What this trial is testing

Pharmacodynamic Study With FLT-PET/CT in Patients With Prostate/Other Solid Malignancies Treated With High Dose Axitinib

Who this might be right for
Solid MalignanciesMetastatic Castrate-resistant Prostate Cancer
University of Wisconsin, Madison 24
Testing effectiveness (Phase 2)Looking for participantsNCT07145255
What this trial is testing

Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors

Who this might be right for
Prostate Cancer Castration-resistant Prostate CancerBreast CancerColo-rectal Cancer+2 more
MBrace Therapeutics 150
Early research (Phase 1)Study completedNCT06517433
What this trial is testing

First-in-Human Dose Escalation Study of XMT-1536 in Cancers Likely to Express NaPi2b

Who this might be right for
Platinum Resistant Ovarian CancerNon Small Cell Lung Cancer Metastatic
Mersana Therapeutics 62
Early research (Phase 1)Study completedNCT03811652
What this trial is testing

A Multiple Ascending Dose Study of MEDI7247 in Advanced or Metastatic Solid Tumors

Who this might be right for
Non Small Cell Lung Cancer Squamous (NSCLC-Sq)Head and Neck Squamous Cell Carcinoma (HNSCC)Small Cell Lung Cancer (SCLC)+3 more
MedImmune LLC 8
Testing effectiveness (Phase 2)Looking for participantsNCT03682289
What this trial is testing

Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors

Who this might be right for
Clear Cell Renal Cell CarcinomaLocally Advanced Pancreatic CancerLocally Advanced Malignant Solid Neoplasm+10 more
Rahul Aggarwal 89
Early research (Phase 1)Not Yet RecruitingNCT07423117
What this trial is testing

ITC-6146RO in Patients With Advanced or Metastatic Cancer Who Have Failed Standard Therapy

Who this might be right for
Metastatic Castration-resistant Prostate CancerNon-small Cell Lung CancerTriple Negative Breast Cancer+1 more
IntoCell, Inc 102
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