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Results for “Resistant Solid Malignancies”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Looking for participantsNCT06413680
What this trial is testing

A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body

Who this might be right for
MelanomaClear-Cell Renal-Cell Carcinoma (ccRCC)Advanced Solid Tumors
Regeneron Pharmaceuticals 240
Testing effectiveness (Phase 2)Looking for participantsNCT04606446
What this trial is testing

Study of PF-07248144 in Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced or Metastatic ER+ HER2- Breast CancerLocally Advanced or Metastatic Castration-resistant Prostate CancerLocally Advanced or Metastatic Non-small Cell Lung Cancer
Pfizer 320
Early research (Phase 1)Looking for participantsNCT07540572
What this trial is testing

Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors

Who this might be right for
ER+, HER 2- Breast CancerNon-small Cell Lung Cancer (NSCLC)Castration-resistant Prostate Cancer (CRPC)+1 more
IDEAYA Biosciences 160
Early research (Phase 1)Ended earlyNCT05242822
What this trial is testing

Evaluate KIN-3248 in Participants With Advanced Tumors Harboring FGFR2 and//or FGFR3 Gene Alterations

Who this might be right for
Solid Tumor, AdultIntrahepatic CholangiocarcinomaUrothelial Carcinoma
Kinnate Biopharma 54
Not applicableActive Not RecruitingNCT05023993
What this trial is testing

The Effect of Exercise and Nicotinamide Riboside Muscle Health and Insulin Resistance in Survivors of Childhood Cancer

Who this might be right for
Hematopoietic and Lymphoid Cell NeoplasmMalignant Solid NeoplasmPrediabetes
City of Hope Medical Center 20
Early research (Phase 1)Study completedNCT01094288
What this trial is testing

Alisertib Participants With Advanced Solid Tumors Including Castration-Resistant Prostate Cancer Receiving a Standard Docetaxel Regimen

Who this might be right for
Advanced Solid TumorsAdenocarcinoma of the Prostate
Millennium Pharmaceuticals, Inc. 41
Early research (Phase 1)Study completedNCT01772004
What this trial is testing

Avelumab in Metastatic or Locally Advanced Solid Tumors (JAVELIN Solid Tumor)

Who this might be right for
Solid Tumors
EMD Serono Research & Development Institute, Inc. 1,756
Early research (Phase 1)Ended earlyNCT02698176
What this trial is testing

A Dose Exploration Study With Birabresib (MK-8628) in Participants With Selected Advanced Solid Tumors (MK-8628-006)

Who this might be right for
NUT Midline Carcinoma (NMC)Triple Negative Breast Cancer (TNBC)Non-small Cell Lung Cancer (NSCLC)+1 more
Merck Sharp & Dohme LLC 13
Testing effectiveness (Phase 2)Looking for participantsNCT05944237
What this trial is testing

HTL0039732 in Participants With Advanced Solid Tumours

Who this might be right for
NeoplasmsProstatic Neoplasms, Castration-ResistantStomach Neoplasms+11 more
Cancer Research UK 150
Testing effectiveness (Phase 2)Active Not RecruitingNCT05081609
What this trial is testing

Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or TransCon TLR7/8 Agonist or Other Anticancer Therapies in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies

Who this might be right for
Advanced Solid TumorLocally Advanced Solid TumorMetastatic Solid Tumor+10 more
Ascendis Pharma Oncology Division A/S 320
Early research (Phase 1)Looking for participantsNCT07029399
What this trial is testing

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

Who this might be right for
HR+ Breast CancerTriple Negative Breast Cancer (TNBC)CCNE1 Amplified Advanced Solid Tumors+1 more
NiKang Therapeutics, Inc. 361
Not applicableLooking for participantsNCT05231655
What this trial is testing

Ex VIvo DEtermiNed Cancer Therapy

Who this might be right for
Bladder CancerKidney CancerMelanoma+3 more
Sheffield Teaching Hospitals NHS Foundation Trust 600
Early research (Phase 1)Looking for participantsNCT05627960
What this trial is testing

First in Human Phase 1 Study of AG01 Anti-Progranulin/GP88 Antibody in Advanced Solid Tumor Malignancies

Who this might be right for
Triple Negative Breast CancerHormone-Resistant Breast CancerNon Small Cell Lung Cancer+1 more
A&G Pharmaceutical Inc. 77
Early research (Phase 1)Looking for participantsNCT06515613
What this trial is testing

CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid Tumors

Who this might be right for
Platinum-resistant Ovarian CancerTesticular CancerEndometrial Cancer
Context Therapeutics Inc. 156
Testing effectiveness (Phase 2)Active Not RecruitingNCT03607890
What this trial is testing

Study of Nivolumab and Relatlimab in Advanced Mismatch Repair Deficient Cancers Resistant to Prior PD-(L)1 Inhibitor

Who this might be right for
Refractory MSI - H Solid Tumors Prior of PD-(L) 1 TherapyMSI-H Tumors
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 38
Testing effectiveness (Phase 2)Looking for participantsNCT04104776
What this trial is testing

Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

Who this might be right for
Advanced Solid TumorDiffuse Large B Cell LymphomaLymphoma, T-Cell+5 more
Novartis Pharmaceuticals 300
Early research (Phase 1)Study completedNCT03517488
What this trial is testing

XmAb®20717 in Subjects With Selected Advanced Solid Tumors

Who this might be right for
MelanomaBreast CarcinomaHepatocellular Carcinoma+25 more
Xencor, Inc. 150
Testing effectiveness (Phase 2)WithdrawnNCT00149032
What this trial is testing

Treatment of Patients With Donor Lymphocytes Sensitized by Antigens Expressed by the Host

Who this might be right for
Hematological MalignancyNeoplasm Metastasis
Hadassah Medical Organization 50
Early research (Phase 1)Ended earlyNCT01288430
What this trial is testing

DS-2248 in Participants With Advanced Solid Tumors

Who this might be right for
Solid TumorsNon-small Cell Lung Carcinoma
Daiichi Sankyo 60
Early research (Phase 1)Looking for participantsNCT06687070
What this trial is testing

APG-2449 Monotherapy or in Combination With PLD in Patients With Platinum-resistant Recurrent OC or Advanced ST

Who this might be right for
Platinum-resistant Recurrent Ovarian CancerAdvanced Solid Tumor
Ascentage Pharma Group Inc. 90
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