Testing effectiveness (Phase 2)UnknownNCT02422719What this trial is testingRadotinib as 3rd or Later Line Therapy in CP-CMLWho this might be right forChronic Myeloid Leukemia Ulsan University Hospital 73
Early research (Phase 1)Study completedNCT01456676What this trial is testingNilotinib and LDE225 in the Treatment of Chronic or Accelerated Phase Myeloid Leukemia in Patients Who Developed Resistance to Prior TherapyWho this might be right forPhiladelphia Chromosome Positive Chronic Myelogenous Leukemia Novartis Pharmaceuticals 11
Large-scale testing (Phase 3)Study completedNCT02260505What this trial is testingEfficiency of Imatinib Treatment Maintenance or Interruption After 3 Years of Adjuvant Treatment in Patients With Gastrointestinal Stromal Tumours (GIST)Who this might be right forGastrointestinal Stromal TumorsResected Gastrointestinal Stromal TumorsNon-metastatic+2 more Centre Leon Berard 136
Not applicableStudy completedNCT04546282What this trial is testingResistance to Oral Therapy in Lung CancerWho this might be right forNon Small Cell Lung Cancer University Hospital, Montpellier 20
Not applicableUnknownNCT01700699What this trial is testingImpact of BRAFV600E Intratumor Heterogeneity in Thyroid Cancer Treated With Tyrosine Kinase InhibitorsWho this might be right forDifferentiated Thyroid Cancer University of Salerno 50
Testing effectiveness (Phase 2)Ended earlyNCT00449761What this trial is testingEfficacy and Safety of LBH589B in Adult Patients With Refractory Chronic Myeloid Leukemia in Accelerated or Blast PhaseWho this might be right forLeukemia, Myeloid, Chronic Novartis Pharmaceuticals 27
Testing effectiveness (Phase 2)Study completedNCT00511303What this trial is testingProtein-Tyrosine Kinase Inhibitor (STI571) for Treatment of Patients With Ph+ Chronic Myeloid LeukemiaWho this might be right forChronic Myeloid Leukemia University of Bologna 200
Early research (Phase 1)Study completedNCT01223898What this trial is testingTo Evaluate the Effects of Multiple Doses of Nilotinib on the Pharmacokinetics and Metabolism of Midazolam in CML Patients With Additional Extension Phase to Evaluate the Safety of NilotinibWho this might be right forChronic Myeloid Leukemia Novartis Pharmaceuticals 19
Testing effectiveness (Phase 2)Ended earlyNCT03807479What this trial is testingStudy in Patients With Chronic LeukemiaWho this might be right forLeukemia, Myeloid, Chronic-Phase GWT-TUD GmbH 18
Testing effectiveness (Phase 2)Study completedNCT01914484What this trial is testingPhase I/II Study of Nilotinib/Ruxolitinb Therapy for TKI Resistant Ph-LeukemiaWho this might be right forChronic Phase Chronic Myeloid LeukemiaAccelerated Phase Chronic Myeloid LeukemiaBlastic Phase Chronic Myeloid Leukemia+2 more University Health Network, Toronto 4
Testing effectiveness (Phase 2)Study completedNCT00117299What this trial is testingPTK787/ZK222584 in the Treatment of Metastatic Gastrointestinal Stromal Tumors Resistant to ImatinibWho this might be right forSarcoma University of Helsinki 45
Early research (Phase 1)Study completedNCT00321581What this trial is testingAZD2171 to Treat Children and Adolescents With Solid Tumors or Acute Myelogenous LeukemiaWho this might be right forRefractory or Recurrent Solid TumorsAcute Myelogenous Leukemia National Cancer Institute (NCI) 18
Testing effectiveness (Phase 2)Ended earlyNCT02629692What this trial is testingSafety and Anti-leukemic Activity of Vodobatinib (K0706) for Treatment of Ph+ CML Resistant/Intolerant to ≥3 Prior CML TherapiesWho this might be right forHealthy (For Part A)Chronic Myeloid Leukemia (for Part B and C) Sun Pharma Advanced Research Company Limited 124
Testing effectiveness (Phase 2)Ended earlyNCT04501614What this trial is testingPonatinib With Chemotherapy in Children, Teenagers, and Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic LeukemiaWho this might be right forPediatric Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ALL)Ph+ Mixed Phenotype Acute Leukemia (MPAL)Philadelphia Chromosome-Like ALL (Ph-like ALL) Takeda 11
Not applicableUnknownNCT05231863What this trial is testingTyrosine Kinase Inhibitors (TKIs) in Trastuzumab Emtansine (T-DM1) Resistant HER2-positive Metastatic Breast Cancer: A Real-world StudyWho this might be right forBreast Cancer The First Affiliated Hospital with Nanjing Medical University 100
Not applicableActive Not RecruitingNCT05020275What this trial is testingResistance to the Tyrosine Kinase Inhibitor Osimertinib and Pharmacokinetics in Non-small Cell Lung CancerWho this might be right forLung Cancer Rennes University Hospital 60
Large-scale testing (Phase 3)Study completedNCT00471328What this trial is testingEfficacy and Safety of Nilotinib (AMN107) Compared With Current Treatment Options in Patients With GIST Who Have Failed Both Imatinib and SunitinibWho this might be right forGastrointestinal Stromal Tumors Novartis Pharmaceuticals 248
Large-scale testing (Phase 3)Not Yet RecruitingNCT07489755What this trial is testingTGRX-678 Chinese Phase III in Chronic Myelogenous Leukemia (CML) PatientsWho this might be right forChronic Myelogenous LeukemiaChronic Myelogenous Leukemia - Chronic Phase Shenzhen TargetRx Co., Ltd. 180
Not applicableStudy completedNCT04222335What this trial is testingUnderstanding and Overcoming the Early Adaptive Resistance to EGFR Tyrosine-kinase Inhibitors in Lung Cancer PatientsWho this might be right forLung Cancer, Nonsmall Cell University Hospital, Toulouse 47
Testing effectiveness (Phase 2)Ended earlyNCT00451035What this trial is testingEfficacy and Safety of LBH589 in Adult Patients With Refractory Chronic Myeloid Leukemia (CML) in Chronic PhaseWho this might be right forChronic Myeloid Leukemia in Chronic Phase Novartis Pharmaceuticals 29