Post-approval studies (Phase 4)UnknownNCT05529095What this trial is testingSublingual Apomorphine in Refractory Restless Legs SyndromeWho this might be right forRestless Legs Syndrome William Ondo, MD 16
Not applicableUnknownNCT02264600What this trial is testingApelin in Willis Ekbom DiseaseWho this might be right forRestless Legs Syndrome Acibadem University 30
Not applicableStudy completedNCT02559739What this trial is testingSleep Deficiency and Stroke OutcomeWho this might be right forSleep Apnea SyndromesSleep Initiation and Maintenance DisordersInsomnia+2 more Insel Gruppe AG, University Hospital Bern 447
Not applicableStudy completedNCT05196828What this trial is testingExtension Study Evaluating NTX100 Neuromodulation System for Medication-Refractory Primary RLSWho this might be right forRestless Legs Syndrome Noctrix Health, Inc. 103
Not applicableLooking for participantsNCT05321355What this trial is testingMainz Register of Patients With Sleep DisordersWho this might be right forSleep DisorderSleep Disorder ParasomniaNarcolepsy+6 more Johannes Gutenberg University Mainz 500
Large-scale testing (Phase 3)Study completedNCT00333359What this trial is testingXP13512 (Gabapentin Enacarbil) Extension Study in Patients With Restless Legs Syndrome.Who this might be right forRestless Legs Syndrome XenoPort, Inc. 581
Testing effectiveness (Phase 2)UnknownNCT06570941What this trial is testingBenefits of a Cannabidiolic Acid Topical Cream for the Treatment of Restless Leg SyndromeWho this might be right forRestless Legs Syndrome Synthonics Inc 10
Testing effectiveness (Phase 2)Study completedNCT00199446What this trial is testingStudy of Istradefylline (KW-6002) for the Treatment of Restless Legs SyndromeWho this might be right forSleep DisorderRestless Legs Syndrome Kyowa Kirin, Inc. 160
Testing effectiveness (Phase 2)UnknownNCT03755310What this trial is testingTreatment of Restless Legs Syndrome With the Hypocretin Antagonist SuvorexantWho this might be right forRestless Legs Syndrome Diego García-Borreguero, MD, PhD 43
Large-scale testing (Phase 3)UnknownNCT02256215What this trial is testingVitamin D in the Treatment of Primary Restless Legs SyndromeWho this might be right forRestless Legs Syndrome King Abdulaziz University 106
Post-approval studies (Phase 4)WithdrawnNCT03063190What this trial is testingCholecalciferol Supplementation in Restless Leg Syndrome in Patients With Chronic Kidney DiseaseWho this might be right forRestless Leg DisorderRenal Disease BoneRenal Disease, End Stage+3 more University of Sao Paulo General Hospital
Large-scale testing (Phase 3)Study completedNCT00355641What this trial is testingLong-Term Safety Of Ropinirole XR In Patients With Restless Legs SyndromeWho this might be right forRestless Legs Syndrome GlaxoSmithKline 450
Not applicableLooking for participantsNCT05908214What this trial is testingThe Application of Wide Pulse High Frequency Neuromuscular Electrical Stimulation in Disorders Associated With Motoneuron HyperexcitabilityWho this might be right forStrokeCrampRestless Legs Syndrome+1 more University of Lausanne 110
Not applicableStudy completedNCT04698343What this trial is testingNoninvasive Peripheral Nerve Stimulation for Restless Legs Syndrome During Opioid Medication ReductionWho this might be right forRestless Legs Syndrome Noctrix Health, Inc. 21
Not applicableActive Not RecruitingNCT06076499What this trial is testingA Post-Market Study for Long-Term Effectiveness and Safety of the TOMAC System for RLSWho this might be right forRestless Legs Syndrome Noctrix Health, Inc. 325
Large-scale testing (Phase 3)Study completedNCT00263068What this trial is testingAn Extension Trial to Investigate Long-Term Treatment With Transdermal Rotigotine in Idiopathic Restless Legs SyndromeWho this might be right forRestless Legs Syndrome UCB Pharma 279
Not applicableStudy completedNCT07117591What this trial is testingRestless Legs Syndrome and Sleep Quality in Pes PlanusWho this might be right forRestless Legs SyndromeSleep QualityPain+3 more Bozok University 242
Testing effectiveness (Phase 2)Study completedNCT00247364What this trial is testingA Double Blind Crossover Trial of Levetiracetam (Keppra®) and Placebo in the Treatment of Restless Legs Syndrome (RLS)Who this might be right forRestless Legs Syndrome Sleep Health Centers 20
Large-scale testing (Phase 3)Study completedNCT01125033What this trial is testingStudy of Vitamin C, Vitamin E and Their Combination to Treat Restless Legs Syndrome in Hemodialysis PatientsWho this might be right forRestless Legs SyndromeKidney Failure, Chronic Shiraz University of Medical Sciences 60
Not applicableUnknownNCT01327560What this trial is testingSleep Quality and Related Factors in Hemodialysis PatientsWho this might be right forHaemodialysis-induced Symptom Taipei Medical University WanFang Hospital 200