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Results for “Revumenib”

21 trials

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Showing 20 of 21 results

Early research (Phase 1)Looking for participantsNCT06177067
What this trial is testing

Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Who this might be right for
Refractory Acute Myeloid LeukemiaRelapsed Acute Myeloid LeukemiaAcute Leukemia of Ambiguous Lineage
St. Jude Children's Research Hospital 24
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07636564
What this trial is testing

Testing Blinatumomab With or Without Revumenib in Patients With B-cell Acute Lymphoblastic Leukemia With a Genetic Change Requiring More Treatment

Who this might be right for
Acute Leukemia of Ambiguous LineageB Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative+1 more
SWOG Cancer Research Network 90
Early research (Phase 1)Looking for participantsNCT06313437
What this trial is testing

Revumenib in Combination With 7+3 + Midostaurin in AML

Who this might be right for
Acute Myeloid LeukemiaAML, AdultAML With Gene Mutations+2 more
Richard Stone, MD 22
Early research (Phase 1)Study completedNCT05326516
What this trial is testing

Revumenib in Combination With Chemotherapy in Participants With R/R Acute Leukemia

Who this might be right for
Relapsed/Refractory LeukemiasAcute Lymphoblastic LeukemiaAcute Lymphocytic Leukemia+3 more
Syndax Pharmaceuticals 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT05761171
What this trial is testing

Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia

Who this might be right for
Recurrent Acute Leukemia of Ambiguous LineageRecurrent Acute Lymphoblastic LeukemiaRecurrent Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage+9 more
Children's Oncology Group 78
Testing effectiveness (Phase 2)Looking for participantsNCT03013998
What this trial is testing

Study of Biomarker-Based Treatment of Acute Myeloid Leukemia

Who this might be right for
Previously Untreated Relapsed Refractory Acute Myeloid Leukemia
Beat AML, LLC 3,000
Not applicableNo Longer AvailableNCT05918913
What this trial is testing

Expanded Access Program for Revumenib

Who this might be right for
Relapsed/Refractory Acute Leukemia
Syndax Pharmaceuticals
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07563010
What this trial is testing

Menin-Inhibitor Targeted Maintenance in AML

Who this might be right for
Relapsed Adult AMLStem Cell Transplant ComplicationsAcute Myeloid Leukemia+1 more
Center for International Blood and Marrow Transplant Research 144
Testing effectiveness (Phase 2)Looking for participantsNCT06284486
What this trial is testing

A Multi-Site Break Through Cancer Trial: Phase II Study Investigating Dual Inhibition of BCL2 and Menin in AML MRD Using the Combination of Venetoclax and Revumenib

Who this might be right for
Acute Myeloid Leukemia
M.D. Anderson Cancer Center 8
Testing effectiveness (Phase 2)Study completedNCT05731947
What this trial is testing

Evaluation of Revumenib in Participants With Colorectal Cancer and Other Solid Tumors

Who this might be right for
Colorectal CancerSolid Tumors
Syndax Pharmaceuticals 42
Early research (Phase 1)Study completedNCT05406817
What this trial is testing

Study of Radiolabeled Revumenib in Adults With Acute Leukemia

Who this might be right for
Acute Leukemia
Syndax Pharmaceuticals 9
Early research (Phase 1)WithdrawnNCT07052994
What this trial is testing

A Phase Ia/Ib Trial of Revumenib Combined With Cytarabine, Daunorubicin, and Gemtuzumab Ozogamicin (GO) in Frontline and Relapsed /Refractory Pediatric Acute Leukemia Patients

Who this might be right for
Pediatric Acute Leukemia
M.D. Anderson Cancer Center
Large-scale testing (Phase 3)Looking for participantsNCT06652438
What this trial is testing

Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML

Who this might be right for
Acute Myeloid Leukemia, Adult
Stichting Hemato-Oncologie voor Volwassenen Nederland 415
Early research (Phase 1)Not Yet RecruitingNCT07283640
What this trial is testing

A Phase IB Trial of Subcutaneous Blinatumomab in Combination With Revumenib for Patients With KMT2A-rearranged Acute Lymphoblastic Leukemia

Who this might be right for
BlinatumomabRevumenibLymphoblastic Leukemia+1 more
M.D. Anderson Cancer Center 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07605949
What this trial is testing

Revumenib, Azacitidine, and VENetoclax in Newly Diagnosed KMT2A-Rearranged AML

Who this might be right for
Leukemia Acute Myeloid
UNC Lineberger Comprehensive Cancer Center 88
Testing effectiveness (Phase 2)Looking for participantsNCT04065399
What this trial is testing

Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMixed Lineage Acute Leukemia+2 more
Syndax Pharmaceuticals 447
Testing effectiveness (Phase 2)Looking for participantsNCT07356154
What this trial is testing

Revumenib and Mezigdomide in People With Leukemia

Who this might be right for
LeukemiaAcute LeukemiaRelapse Leukemia+5 more
Memorial Sloan Kettering Cancer Center 52
Early research (Phase 1)WithdrawnNCT07498465
What this trial is testing

Find the Highest Dose of SNDX-5613 (Revumenib) as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, and Mixed Phenotype Acute Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaChildhood Acute Lymphoblastic Leukemia+3 more
Children's Oncology Group
Testing effectiveness (Phase 2)Looking for participantsNCT06229912
What this trial is testing

A Phase II Study of the Menin Inhibitor Revumenib in Leukemia Associated With Upregulation of HOX Genes

Who this might be right for
LeukemiaHOX Gene
M.D. Anderson Cancer Center 40
Large-scale testing (Phase 3)Looking for participantsNCT07211958
What this trial is testing

Study of Revumenib in Combination With Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia (AML) With a NPM1 Mutation

Who this might be right for
Acute Myeloid Leukemias
Syndax Pharmaceuticals 468
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