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Results for “Ribociclib”

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Showing 20 of 0 results

Not applicableNot Yet RecruitingNCT07817212
What this trial is testing

ESR1Real World Assessment Prevalence Study

Who this might be right for
HR+/HER2- aBC Undergoing 1L Treatment With CDK4/6i (Palbociclib, Abemaciclib or Ribociclib) and AI (Anastrozole or Letrozole)
Institut fuer Frauengesundheit 1,550
Testing effectiveness (Phase 2)Looking for participantsNCT07405801
What this trial is testing

A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast Cancer

Who this might be right for
Breast Cancer
Hoffmann-La Roche 80
Early research (Phase 1)Study completedNCT02370706
What this trial is testing

Study of the Safety of PIM447 in Combination With Ruxolitinib (INC424) and LEE011 in Patients With Myelofibrosis

Who this might be right for
Myelofibrosis
Novartis Pharmaceuticals 15
Testing effectiveness (Phase 2)Looking for participantsNCT05816655
What this trial is testing

Comparison of Clinical Efficacy Between Letrozole + Ribociclib and Fulvestrant + Letrozole + Ribociclib in Hormone Receptor Positive, HER2 Negative Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer
Korea University Guro Hospital 202
Testing effectiveness (Phase 2)Looking for participantsNCT06062498
What this trial is testing

Elacestrant vs Elacestrant Plus a CDK4/6 Inhibitor in Patients With ERpositive/HER2-negative Advanced or Metastatic Breast Cancer

Who this might be right for
Estrogen-receptor-positive Breast CancerHER2/Neu-Negative Breast CancerAdvanced Breast Cancerv+1 more
Northwestern University 174
Post-approval studies (Phase 4)Ended earlyNCT04657679
What this trial is testing

Pharmacokinetics and Pharmacogenomics of Ribociclib in Race-based Cohorts

Who this might be right for
Breast Cancer
Georgetown University 21
Testing effectiveness (Phase 2)Ended earlyNCT02555189
What this trial is testing

Enzalutamide With Ribociclib in Treating Patients With Metastatic Castrate-Resistant, Chemotherapy Naive Prostate Cancer That Retains Retinoblastoma Expression

Who this might be right for
Castration-Resistant Prostate CarcinomaMetastatic Prostate CarcinomaProstate Carcinoma Metastatic in the Bone+1 more
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 52
Testing effectiveness (Phase 2)Study completedNCT02420691
What this trial is testing

Ribociclib in Treating Patients With Advanced Neuroendocrine Tumors of Foregut Origin

Who this might be right for
Advanced Digestive System Neuroendocrine NeoplasmDuodenal Neuroendocrine Tumor G1Functional Pancreatic Neuroendocrine Tumor+5 more
M.D. Anderson Cancer Center 21
Early research (Phase 1)Ended earlyNCT04315233
What this trial is testing

Ribociclib&Belinostat In Patients w Metastatic Triple Neg Breast Cancer & Recurrent Ovarian Cancer w Response Prediction By Genomics

Who this might be right for
Metastatic Breast CancerRecurrent Ovarian Carcinoma
University of Utah 12
Not applicableStudy completedNCT06705504
What this trial is testing

A Real-world Study of Effectiveness and Safety in HR+/HER2- Breast Cancer Patients Treated With Ribociclib or Alpelisib

Who this might be right for
Hormone Receptor Positive HER-2 Negative Breast Cancer
Novartis 435
Testing effectiveness (Phase 2)Active Not RecruitingNCT05625087
What this trial is testing

Detection of Tumor DNA in the Blood of Patients Receiving Standard Therapy for Hormone Receptor-positive (HR+) Non-HER2 Expressing (HER2-) Metastatic Breast Cancer as a Tool to Select Those Who May Benefit From the Next Course of Fulvestrant in Combination With Alpelisib or Ribociclib

Who this might be right for
Breast Cancer Stage IV
UNICANCER 162
Very early researchStudy completedNCT03834740
What this trial is testing

A Phase 0/I Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for Resection

Who this might be right for
Glioblastoma MultiformeGlioma of Brain
St. Joseph's Hospital and Medical Center, Phoenix 27
Not applicableStudy completedNCT06619704
What this trial is testing

Observational Retrospective Study to Assess the Use of Ribociclib in Patients With HR+, HER2- Metastatic Breast Cancer Treated With Chemotherapy

Who this might be right for
Metastatic Breast Cancer
Novartis Pharmaceuticals 194
Not applicableLooking for participantsNCT07407439
What this trial is testing

Real-world Studies of CDK4/6 Inhibitors

Who this might be right for
Breast Cancer
Tianjin Medical University Cancer Institute and Hospital 245
Large-scale testing (Phase 3)Looking for participantsNCT07647328
What this trial is testing

A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast Cancer

Who this might be right for
ER-Positive HER2-Negative Breast Cancer
AstraZeneca 150
Testing effectiveness (Phase 2)Study completedNCT06375707
What this trial is testing

First-Line Ribociclib Plus Endocrine Therapy Versus Chemotherapy With or Without Subsequent Endocrine Therapy in Patients With Rapidly Progressive HR-Positive/HER2-Negative Advanced Breast Cancer

Who this might be right for
Advanced Breast Cancer
The First Affiliated Hospital with Nanjing Medical University 74
Very early researchActive Not RecruitingNCT02933736
What this trial is testing

Ribociclib (LEE011) in Preoperative Glioma and Meningioma Patients

Who this might be right for
Glioblastoma MultiformeMeningioma
Nader Sanai 48
Large-scale testing (Phase 3)Looking for participantsNCT07391774
What this trial is testing

Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

Who this might be right for
Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIC Breast Cancer AJCC v8+2 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Study completedNCT02187783
What this trial is testing

LEE011 for Patients With CDK4/6 Pathway Activated Tumors (SIGNATURE)

Who this might be right for
Tumors With CDK4/6 Pathway Activation
Novartis Pharmaceuticals 106
Early research (Phase 1)Looking for participantsNCT05996107
What this trial is testing

Study of Ribociclib Administered Concurrently With Postoperative Radiation Therapy in Patients With High-Risk, HR+/HER2- Breast Cancer

Who this might be right for
Breast Cancer
University of Michigan Rogel Cancer Center 30
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