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Results for “Richter Transformation”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04623541
What this trial is testing

Safety and Efficacy Study of Epcoritamab in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter's Syndrome

Who this might be right for
Relapsed/Refractory Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaRichter's Syndrome+1 more
Genmab 194
Early research (Phase 1)Active Not RecruitingNCT03321643
What this trial is testing

Testing the Addition of an Immunotherapy Agent, Atezolizumab, When Given With the Usual Chemo-Immunotherapy Drug Combination (Rituximab Plus Gemcitabine and Oxaliplatin) for Relapsed/Refractory (That Has Come Back or Not Responded to Treatment) Transformed Diffuse Large B-Cell Lymphoma

Who this might be right for
Recurrent Diffuse Large B-Cell LymphomaRecurrent Transformed Non-Hodgkin LymphomaRefractory Diffuse Large B-Cell Lymphoma+3 more
National Cancer Institute (NCI)
Early research (Phase 1)WithdrawnNCT02238522
What this trial is testing

Phase 1 Study Evaluating ZEN003365 in Relapsed/Refractory Lymphoproliferative Malignancies or Relapsed/Refractory AML

Who this might be right for
Lymphoproliferative MalignanciesAcute Myeloid Leukemia
Zenith Epigenetics
Testing effectiveness (Phase 2)Looking for participantsNCT06863402
What this trial is testing

Nemtabrutinib and Pembrolizumab for the Treatment of Richter Transformation, Diffuse Large B-cell Lymphoma Subtype

Who this might be right for
Richter SyndromeDiffuse Large B-Cell LymphomaChronic Lymphocytic Leukemia
Roswell Park Cancer Institute 32
Testing effectiveness (Phase 2)WithdrawnNCT02718755
What this trial is testing

Phase II Study of Fludarabine, Cytarabine (ARA-C) and Erwinase IV in Patients With Relapsed or Refractory Hematologic Malignancies

Who this might be right for
Hematologic Malignancy
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Study completedNCT01217749
What this trial is testing

Efficacy and Safety Study of PCI-32765 Combine With Ofatumumab in CLL

Who this might be right for
B-cell Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaProlymphocyctic Leukemia+1 more
Pharmacyclics LLC. 71
Early research (Phase 1)Looking for participantsNCT04771572
What this trial is testing

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

Who this might be right for
Non Hodgkin LymphomaRichter TransformationMultiple Myeloma+10 more
Newave Pharmaceutical Inc 100
Early research (Phase 1)Study completedNCT02924402
What this trial is testing

Study to Evaluate Safety and Tolerability of XmAb13676 (Plamotamab) in Patients With CD20-expressing Hematologic Malignancies

Who this might be right for
B-cell Non-Hodgkins LymphomaChronic Lymphocytic Leukemia
Xencor, Inc. 154
Testing effectiveness (Phase 2)Ended earlyNCT03121534
What this trial is testing

Ibrutinib, Nivolumab and Blinatumomab in Richter Transformation

Who this might be right for
Hematopoietic/Lymphoid CancerRichter's Transformation
M.D. Anderson Cancer Center 9
Early research (Phase 1)Study completedNCT03113695
What this trial is testing

Obinutuzumab, High Dose Methylprednisolone (HDMP), and Lenalidomide for the Treatment of Patients With Richter's Syndrome

Who this might be right for
Richter's SyndromeCLL
University of California, San Diego 4
Testing effectiveness (Phase 2)Study completedNCT02530515
What this trial is testing

Ex Vivo-activated Autologous Lymph Node Lymphocytes in Treating Patients With Chronic Lymphocytic Leukemia

Who this might be right for
AnemiaCancer FatigueChronic Lymphocytic Leukemia+11 more
M.D. Anderson Cancer Center 8
Early research (Phase 1)Study completedNCT03892044
What this trial is testing

Duvelisib and Nivolumab in Treating Patients With Richter Syndrome or Transformed Follicular Lymphoma

Who this might be right for
Chronic Lymphocytic LeukemiaRecurrent Diffuse Large B-Cell LymphomaRefractory Diffuse Large B-Cell Lymphoma+5 more
David Bond, MD 7
Early research (Phase 1)Looking for participantsNCT07424833
What this trial is testing

APG-3288 in Relapsed/Refractory Blood Cancers

Who this might be right for
Relapsed/Refractory Hematological MalignanciesRelapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Leukemia (CLL/SLLRelapsed/Refractory Diffuse Large B-cell Lymphoma (DLBCL; Including Richter Transformation)+4 more
Ascentage Pharma Group Inc.
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07735533
What this trial is testing

UB-VV400 With Rapamycin in Relapsed/Refractory B-cell Malignancies

Who this might be right for
Lymphoma, B CellLymphoma Non-HodgkinHigh Grade B Cell Lymphoma+4 more
Umoja Biopharma 274
Large-scale testing (Phase 3)Not Yet RecruitingNCT07220187
What this trial is testing

Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID Trial

Who this might be right for
Richter SyndromeTransformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell LymphomaTransformed Small Lymphocytic Lymphoma to Diffuse Large B-Cell Lymphoma
SWOG Cancer Research Network 102
Testing effectiveness (Phase 2)Looking for participantsNCT05536349
What this trial is testing

Time-limited Triplet Combination of Pirtobrutinib, Venetoclax, and Obinutuzumab for Patients With Treatment-naïve Chronic Lymphocytic Leukemia (CLL) or Richter Transformation (RT)

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 60
Testing effectiveness (Phase 2)Study completedNCT04939363
What this trial is testing

Evaluate Efficacy & Safety of Obinutuzumab, Ibrutinib, and Venetoclax in Richter's Syndrome;

Who this might be right for
Richter's Syndrome
Bnai Zion Medical Center 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT03162536
What this trial is testing

Nemtabrutinib (MK-1026) in Participants With Relapsed or Refractory Hematologic Malignancies (ARQ 531-101/MK-1026-001)

Who this might be right for
Lymphoma, B-CellSmall Lymphocytic LymphomaChronic Lymphocytic Leukemia+6 more
ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA) 190
Testing effectiveness (Phase 2)Looking for participantsNCT05873712
What this trial is testing

Zanubrutinib and Lisocabtagene Maraleucel for the Treatment of Richter's Syndrome

Who this might be right for
Recurrent Transformed Chronic Lymphocytic LeukemiaRefractory Transformed Chronic Lymphocytic LeukemiaTransformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma+5 more
Aseel Alsouqi 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT03899337
What this trial is testing

A Trial of CHOP-R Therapy, With or Without Acalabrutinib, in Patients With Newly Diagnosed Richter's Syndrome

Who this might be right for
Richter Syndrome
University of Birmingham 72
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