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Results for “Richter Transformation Lymphoma”

56 trials

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Showing 20 of 56 results

Early research (Phase 1)Active Not RecruitingNCT03479268
What this trial is testing

Pevonedistat and Ibrutinib in Treating Participants With Relapsed or Refractory CLL or Non-Hodgkin Lymphoma

Who this might be right for
B-Cell Prolymphocytic LeukemiaRecurrent Chronic Lymphocytic LeukemiaRecurrent Diffuse Large B-Cell Lymphoma+15 more
City of Hope Medical Center 18
Testing effectiveness (Phase 2)Looking for participantsNCT04491370
What this trial is testing

Autologous Stem Cell Transplant Followed by Polatuzumab Vedotin in Patients With B-cell Non-Hodgkin and Hodgkin Lymphoma

Who this might be right for
B-cell LymphomaBurkitt LymphomaDiffuse Large B Cell Lymphoma+6 more
New York Medical College 20
Testing effectiveness (Phase 2)WithdrawnNCT02285244
What this trial is testing

Sotrastaurin Acetate in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Leukemia, Prolymphocytic Leukemia, or Richter's Transformation

Who this might be right for
Prolymphocytic LeukemiaRecurrent Mantle Cell LymphomaRecurrent Small Lymphocytic Lymphoma+2 more
James Blachly
Testing effectiveness (Phase 2)Ended earlyNCT02378038
What this trial is testing

PNT2258 for Treatment of Patients With Richter's Transformation (Brighton)

Who this might be right for
Richter's Transformation
Sierra Oncology LLC - a GSK company 5
Early research (Phase 1)Not Yet RecruitingNCT07424833
What this trial is testing

APG-3288 in Relapsed/Refractory Blood Cancers

Who this might be right for
Relapsed/Refractory Hematological MalignanciesRelapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Leukemia (CLL/SLLRelapsed/Refractory Diffuse Large B-cell Lymphoma (DLBCL; Including Richter Transformation)+4 more
Ascentage Pharma Group Inc.
Testing effectiveness (Phase 2)Study completedNCT01171378
What this trial is testing

Study of Cyclophosphamide, Hydroxydaunorubicin, Oncovin, Prednisone (CHOP) With Ofatumumab in Patients With Richter's Syndrome

Who this might be right for
Richter's Syndrome
University of Oxford 43
Testing effectiveness (Phase 2)Study completedNCT02362035
What this trial is testing

ACP-196 (Acalabrutinib) in Combination With Pembrolizumab, for Treatment of Hematologic Malignancies

Who this might be right for
Follicular Lymphoma (FL)CLLSmall Lymphocytic Lymphoma (SLL)+10 more
Acerta Pharma BV 161
Early research (Phase 1)Enrolling By InvitationNCT07168486
What this trial is testing

CD19.20.22 CAR T-cells for Patients With Relapsed/Refractory B-Cell Lymphomas

Who this might be right for
B-Cell LymphomaDiffuse Large B Cell Lymphoma (DLBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)+7 more
University of Maryland, Baltimore 15
Testing effectiveness (Phase 2)Looking for participantsNCT05873712
What this trial is testing

Zanubrutinib and Lisocabtagene Maraleucel for the Treatment of Richter's Syndrome

Who this might be right for
Recurrent Transformed Chronic Lymphocytic LeukemiaRefractory Transformed Chronic Lymphocytic LeukemiaTransformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma+5 more
Aseel Alsouqi 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT05458297
What this trial is testing

Zilovertamab Vedotin (MK-2140) as Monotherapy and in Combination in Participants With Aggressive and Indolent B-cell Malignancies (MK-2140-006)

Who this might be right for
Chronic Lymphocytic LeukemiaMantle Cell LymphomaFollicular Lymphoma+1 more
Merck Sharp & Dohme LLC 189
Not applicableNot Yet RecruitingNCT05923502
What this trial is testing

(CHANT)Real World Study of Duvelisib in the Treatment of Non-Hodgkin's Lymphoma (NHL)

Who this might be right for
Follicular LymphomaChronic Lymphocytic Leukemia/Small Lymphocytic LymphomaRichter Syndrome+3 more
Ruijin Hospital 200
Testing effectiveness (Phase 2)Active Not RecruitingNCT02846623
What this trial is testing

Atezolizumab, Obinutuzumab, and Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Relapsed or Refractory Richter Syndrome

Who this might be right for
Chronic Lymphocytic LeukemiaRecurrent Transformed Chronic Lymphocytic LeukemiaRefractory Transformed Chronic Lymphocytic Leukemia+2 more
M.D. Anderson Cancer Center 50
Large-scale testing (Phase 3)Not Yet RecruitingNCT07220187
What this trial is testing

Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID Trial

Who this might be right for
Richter SyndromeTransformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell LymphomaTransformed Small Lymphocytic Lymphoma to Diffuse Large B-Cell Lymphoma
SWOG Cancer Research Network 102
Testing effectiveness (Phase 2)Ended earlyNCT05537766
What this trial is testing

Study of Brexucabtagene Autoleucel in Adults With Rare B-cell Malignancies

Who this might be right for
Relapsed/Refractory Waldenstrom MacroglobulinemiaRelapsed/Refractory Richter TransformationRelapsed/Refractory Burkitt Lymphoma+1 more
Kite, A Gilead Company 19
Testing effectiveness (Phase 2)Study completedNCT01217749
What this trial is testing

Efficacy and Safety Study of PCI-32765 Combine With Ofatumumab in CLL

Who this might be right for
B-cell Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaProlymphocyctic Leukemia+1 more
Pharmacyclics LLC. 71
Testing effectiveness (Phase 2)Study completedNCT00304005
What this trial is testing

VNP40101M in Treating Patients With Richter Syndrome or Refractory or Relapsed Chronic Lymphocytic Leukemia or Other Lymphoproliferative Disorders

Who this might be right for
LeukemiaLymphoma
Vion Pharmaceuticals 35
Testing effectiveness (Phase 2)Ended earlyNCT04305444
What this trial is testing

Study of a Triple Combination Therapy, DTRM-555, in Patients With R/R CLL or R/R Non-Hodgkin's Lymphomas

Who this might be right for
Relapsed Chronic Lymphocytic LeukemiaRefractory Chronic Lymphocytic LeukemiaDiffuse Large B Cell Lymphoma+2 more
Zhejiang DTRM Biopharma 55
Early research (Phase 1)Study completedNCT03833180
What this trial is testing

Zilovertamab Vedotin (MK-2140) (VLS-101) in Participants With Hematologic Malignancies (MK-2140-001)

Who this might be right for
Chronic Lymphocytic LeukemiaMantle Cell LymphomaFollicular Lymphoma+9 more
VelosBio Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 91
Early research (Phase 1)Not Yet RecruitingNCT07539688
What this trial is testing

Phase I Clinical Study on the Safety and Efficacy of CY-219 CAR-T Cell Injection in the Treatment of Relapsed/Refractory B-Cell Lymphoma

Who this might be right for
Relapsed/Refractory B-cell LymphomaDiffuse Large B-cell LymphomaInert B-cell Lymphoma Transformed Into Large B-cell Lymphoma (Excluding Richter Transformation, THRLBCL, and BL)
Institute of Hematology & Blood Diseases Hospital, China 18
Testing effectiveness (Phase 2)Looking for participantsNCT05388006
What this trial is testing

Acalabrutinib, Venetoclax and Durvalumab for the Treatment of Richter Transformation From Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Who this might be right for
Chronic Lymphocytic LeukemiaRichter SyndromeSmall Lymphocytic Lymphoma
Mayo Clinic 27
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