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Results for “SCN1A”

12 trials

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Showing 12 of 12 results

Testing effectiveness (Phase 2)Looking for participantsNCT05419492
What this trial is testing

A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome

Who this might be right for
Dravet Syndrome
Encoded Therapeutics 47
Testing effectiveness (Phase 2)Study completedNCT03650452
What this trial is testing

A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-935 (OV935) as an Adjunctive Therapy in Pediatric Participants With Developmental and/or Epileptic Encephalopathies

Who this might be right for
EpilepsyDravet SyndromeLennox-Gastaut Syndrome
Takeda 141
Not applicableLooking for participantsNCT01238250
What this trial is testing

Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight

Who this might be right for
16P11.2 Deletion Syndrome16p11.2 Duplications1Q21.1 Deletion+181 more
Simons Searchlight 100,000
Not applicableLooking for participantsNCT06504511
What this trial is testing

SCN1A Horizons A Natural History Study of SCN1A-related Epilepsies in the United Kingdom

Who this might be right for
SCN1ADravet SyndromeEpilepsy
NHS Greater Glasgow and Clyde 400
Not applicableLooking for participantsNCT06967727
What this trial is testing

Registry and Natural History of Epilepsy-Dyskinesia Syndromes

Who this might be right for
Epilepsy-DyskinesiaEpilepsyDyskinesia+11 more
Boston Children's Hospital 700
Testing effectiveness (Phase 2)Active Not RecruitingNCT06112275
What this trial is testing

A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (Australia Only)

Who this might be right for
Dravet Syndrome
Encoded Therapeutics 4
Not applicableNo Longer AvailableNCT02239276
What this trial is testing

Expanded Access Use of Stiripentol in Dravet Syndrome or Sodium Channel Mutation Epileptic Encephalopathies

Who this might be right for
Dravet SyndromeEpileptic Encephalopathies Associated With SCN1A Mutations
Cook Children's Health Care System
Not applicableLooking for participantsNCT06585605
What this trial is testing

A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes

Who this might be right for
Epilepsy in ChildrenDyskinesiasMovement Disorders in Children+7 more
Boston Children's Hospital 500
Testing effectiveness (Phase 2)Active Not RecruitingNCT06283212
What this trial is testing

A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome

Who this might be right for
Dravet Syndrome
Encoded Therapeutics 5
Not applicableEnded earlyNCT04537832
What this trial is testing

Natural History Study of Infants and Children With Developmental and Epileptic Encephalopathies

Who this might be right for
Dravet Syndrome
Encoded Therapeutics 58
Not applicableLooking for participantsNCT05651204
What this trial is testing

GABA Biomarkers in Dravet Syndrome

Who this might be right for
Dravet Syndrome
Cook Children's Health Care System 36
Not applicableLooking for participantsNCT07251673
What this trial is testing

Longitudinal Study of Phenotypic and Developmental Severity in Patients With Dravet Syndrome With SCN1A Gene Mutation

Who this might be right for
Dravet Syndrome
Assistance Publique - Hôpitaux de Paris 50