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Results for “SF3B1 Gene Mutation”

5 trials

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Showing 5 of 5 results

Early research (Phase 1)Looking for participantsNCT07137637
What this trial is testing

HPB-092 for the Treatment of Relapsed and Refractory Acute Myeloid Leukemia

Who this might be right for
Relapsed and Refractory Acute Myeloid Leukemia (RR-AML)
Hangzhou Polymed Biopharmaceuticals, Inc. 60
Early research (Phase 1)Not Yet RecruitingNCT07753148
What this trial is testing

Safety and Tolerability of REGN17235 in Adult Participants With Clonal Cytopenia of Undetermined Significance and Low-Risk Myelodysplastic Syndrome With SF3B1 Mutation

Who this might be right for
Clonal Cytopenia of Undetermined Significance (CCUS)Low-Risk Myelodysplastic Syndrome (LR-MDS)
Regeneron Pharmaceuticals 52
Not applicableActive Not RecruitingNCT04447651
What this trial is testing

Patient Response to Immunotherapy Using Spliceosome Mutational Markers (PRISMM)

Who this might be right for
Metastatic Solid TumorSF3B1 Gene MutationSpliceosome Mutation+2 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 6
Not applicableNot Yet RecruitingNCT07113132
What this trial is testing

Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia ALLChronic Lymphocytic Leukemia (CLL)
Safaa Ali 84
Testing effectiveness (Phase 2)Temporarily pausedNCT04278768
What this trial is testing

Dose Escalation/ Expansion Study of CA-4948 as Monotherapy in Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Who this might be right for
Acute Myelogenous LeukemiaMyelodysplastic Syndrome
Curis, Inc. 366