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Results for “SHR-A1811”

74 trials

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Showing 20 of 74 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07417241
What this trial is testing

SHR-A1811 vs Pyrotinib/Capecitabine in Trastuzumab-Resistant HER2+ Advanced Breast Cancer: A Randomized Study

Who this might be right for
Breast CancerHER2-positive Breast Cancer
Peking University Cancer Hospital & Institute 100
Large-scale testing (Phase 3)Looking for participantsNCT06430437
What this trial is testing

SHR-A1811 in First-line Treatment of Patients With Advanced or Metastatic Non-small Cell Lung Cancer With HER2 Mutations

Who this might be right for
Non-Small Cell Lung Cancer With HER2- Mutations
Jiangsu HengRui Medicine Co., Ltd. 300
Testing effectiveness (Phase 2)Looking for participantsNCT06718933
What this trial is testing

Study of SHR-A1811 Combined With Pyrotinib and Bevacizumab in Advanced Breast Cancer With Brain Metastasis

Who this might be right for
Breast Cancer MetastaticBreast Cancer Brain Metastases
Fudan University 74
Early research (Phase 1)Not Yet RecruitingNCT07581574
What this trial is testing

Neoadjuvant SHR-A1811 and SHR-A1701 for Potentially Immunotherapy-Sensitive GC or GEJ Adenocarcinoma

Who this might be right for
Gastric or Gastroesophageal Junction Adenocarcinoma
The First Affiliated Hospital with Nanjing Medical University 12
Testing effectiveness (Phase 2)Looking for participantsNCT07817082
What this trial is testing

Phase II Study of SHR-A1811 for Ultra-Low HER2 Advanced Breast Cancer

Who this might be right for
Advanced Breast Cancer With Ultra-Low HER2 Expression
Tianjin Medical University Cancer Institute and Hospital 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06973525
What this trial is testing

This Study Aims to Optimize Neoadjuvant Therapy for HER2-positive Breast Cancer by Implementing a Dynamic Monitoring-guided Treatment Strategy.

Who this might be right for
HER2-positive Breast Cancer
Hebei Medical University Fourth Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT05635487
What this trial is testing

SHR-A1811 Monotherapy or Combined With Pyrotinib Maleate as Neoadjuvant Treatment in HER2-positive Breast Cancer Patients

Who this might be right for
HER2-positive Breast Cancer
Shengjing Hospital 65
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06990516
What this trial is testing

SHR - A1811 Injection in the Treatment of Platinum-sensitive Recurrent Ovarian Cancer

Who this might be right for
Ovarian Cancer
Tongji Hospital 90
Early research (Phase 1)Looking for participantsNCT07275242
What this trial is testing

A Clinical Study of SHR-A1811(sc) Subcutaneous Injection in Patients With Solid Tumor

Who this might be right for
Solid Tumor
Suzhou Suncadia Biopharmaceuticals Co., Ltd. 107
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06975462
What this trial is testing

A Phase II Study of SHR-A1811 Combined With Radiotherapy in HER2-positive and HER2-low Breast Cancer Brain Metastases

Who this might be right for
Breast Cancer Metastatic
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07129187
What this trial is testing

SHR-A1811 for HER2-positive Breast Cancer With Suboptimal Neoadjuvant Response

Who this might be right for
Early Breast CancerHER2 + Breast CancerStage II Breast Cancer+1 more
Chuan Wang 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07528898
What this trial is testing

Neoadjuvant SHR-A1811 Combined With Pertuzumab in HER2-Positive Breast Cancer: An Exploratory Clinical Study.

Who this might be right for
Breast Cancer
Hebei Medical University Fourth Hospital 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT06413745
What this trial is testing

Phase II Clinical Study of SHR-A1811 in Patients With HER2 Expression / Amplification of Locally Advanced Unresectable or Recurrent Metastatic Biliary Tract Cancer

Who this might be right for
HER2 Expression / Amplification in Patients With Biliary Tract Cancer
Jiangsu HengRui Medicine Co., Ltd. 59
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06666166
What this trial is testing

SHR-A1811 Combined with Apatinib in the Treatment of Advanced Gastric or Gastroesophageal Junction Adenocarcinoma and Colorectal Cancer

Who this might be right for
Advanced Gastric CarcinomaAdvanced Gastroesophageal Junction AdenocarcinomaAdvanced Colorectal Cancer
Yunpeng Liu 28
Large-scale testing (Phase 3)Active Not RecruitingNCT06126640
What this trial is testing

A Phase III, Active-Controlled Study of SHR-A1811 Versus Trastuzumab Emtansine (T-DM1) in HER2-Positive Primary Breast Cancer Participants With Residual Invasive Disease Following Neoadjuvant Therapy

Who this might be right for
HER2-Positive Primary Breast Cancer Participants With Residual Invasive Disease Following Neoadjuvant Therapy
Jiangsu HengRui Medicine Co., Ltd. 1,615
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07796763
What this trial is testing

A Global Trial of Trastuzumab Rezetecan (SHR-A1811) in Combination With Chemotherapy and Bevacizumab as First-Line Treatment in Patients With Advanced Colorectal Cancer Expressing HER2

Who this might be right for
Advanced Colorectal Cancer Expressing HER2
Jiangsu HengRui Medicine Co., Ltd. 48
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07317778
What this trial is testing

Chemotherapy With or Without Adebrelimab and T-DXh as Neoadjuvant Therapy for HR+/HER2 Low Early Stage Breast Cancer

Who this might be right for
Breast Cancer Early Stage Breast Cancer (Stage 1-3)HR Positive/HER2 Low Breast Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 249
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07618923
What this trial is testing

Neoadjuvant Dalpiciclib + AI → SHR-A1811 for HR+/HER2-Low Breast Cancer

Who this might be right for
Breast CancerHR Positive/HER2 Low Breast Cancer
Tang-Du Hospital 20
Testing effectiveness (Phase 2)UnknownNCT05353361
What this trial is testing

A Phase Ib/II Study of SHR-A1811 Injection in Breast Cancer

Who this might be right for
Breast Cancer
Jiangsu HengRui Medicine Co., Ltd. 402
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06788197
What this trial is testing

SHR-A1811 and Fulvestrant, With or Without HS-10352, in Locally Advanced or Metastatic Breast Cancer Patients

Who this might be right for
Breast CancerLocally Advanced or Metastatic Breast Cancer
Henan Cancer Hospital 52
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