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Results for “SMARCA4 Gene Mutation”

7 trials

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Showing 7 of 7 results

Early research (Phase 1)Study completedNCT05639751
What this trial is testing

PRT3789 Monotherapy and in Combo w/Docetaxel in Participants w/Advanced or Metastatic Solid Tumors w/SMARCA4 Mutation

Who this might be right for
Advanced Solid TumorMetastatic Solid TumorNon-small Cell Lung Cancers+1 more
Prelude Therapeutics Incorporated 135
Testing effectiveness (Phase 2)Study completedNCT03213665
What this trial is testing

Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Hodgkin LymphomaAnn Arbor Stage III Non-Hodgkin Lymphoma+38 more
National Cancer Institute (NCI) 20
Not applicableStudy completedNCT04257045
What this trial is testing

Factors Influencing Cascade Testing Among Women With Hereditary Gynecological Cancers and Their Relatives

Who this might be right for
Breast CarcinomaDeleterious CDH1 Gene MutationDeleterious DICER1 Gene Mutation+6 more
M.D. Anderson Cancer Center 46
Early research (Phase 1)Looking for participantsNCT07284186
What this trial is testing

First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Esophageal Squamous Cell CarcinomaGastric AdenocarcinomaGastric Squamous Cell Carcinoma+7 more
Plexium, Inc. 155
Testing effectiveness (Phase 2)Ended earlyNCT06682806
What this trial is testing

PRT3789 in Combination With Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation

Who this might be right for
Advanced Solid TumorEsophageal CancerMetastatic Solid Tumor+2 more
Prelude Therapeutics Incorporated 6
Early research (Phase 1)Ended earlyNCT06560645
What this trial is testing

PRT7732, an Oral SMARCA2 Degrader, in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation

Who this might be right for
Advanced Solid TumorMetastatic Solid TumorNon-small Cell Lung Carcinoma+7 more
Prelude Therapeutics Incorporated 42
Not applicableLooking for participantsNCT01238250
What this trial is testing

Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight

Who this might be right for
16P11.2 Deletion Syndrome16p11.2 Duplications1Q21.1 Deletion+184 more
Simons Searchlight 100,000