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Results for “SMARCB1-Deficient Malignancies”

4 trials

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Showing 4 of 4 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT05407441
What this trial is testing

Tazemetostat+Nivo/Ipi in INI1-Neg/SMARCA4-Def Tumors

Who this might be right for
Atypical Teratoid Rhabdoid TumorINI1 (SMARCB1)-Deficient Primary CNS Malignant TumorsSMARCA4-deficient Primary CNS Malignant Tumors+4 more
Susan Chi, MD 49
Testing effectiveness (Phase 2)Active Not RecruitingNCT06444880
What this trial is testing

Phase II Trial of Ubamatamab Alone or in Combination With Cemiplimab in MUC16-Expressing SMARCB1-Deficient Malignancies

Who this might be right for
SMARCB1-Deficient MalignanciesEpithelioid SarcomaRenal Medullary Carcinoma
M.D. Anderson Cancer Center 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT05286801
What this trial is testing

Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors

Who this might be right for
Atypical Teratoid/Rhabdoid TumorEpithelioid SarcomaKidney Medullary Carcinoma+15 more
National Cancer Institute (NCI) 86
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07816770
What this trial is testing

MANTIS-RCC: Toripalimab-Axitinib Induction in TLS-Positive Advanced Non-Clear Cell and Renal Medullary Carcinomas

Who this might be right for
Metastatic Non-Clear Cell Renal Cell CarcinomaMetastatic Renal Medullary Carcinomas
Fudan University 30