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Results for “SPG50”

5 trials

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Showing 5 of 5 results

Testing effectiveness (Phase 2)Looking for participantsNCT05518188
What this trial is testing

Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt)

Who this might be right for
Spasticity, MuscleMicrocephalyIntellectual Deficiency+3 more
Elpida Therapeutics SPC 4
Not applicableLooking for participantsNCT05354622
What this trial is testing

Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)

Who this might be right for
Hereditary Spastic ParaplegiaNeurodegenerative DiseasesPediatric Disorder+3 more
Boston Children's Hospital 200
Not applicableLooking for participantsNCT04712812
What this trial is testing

Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia

Who this might be right for
Hereditary Spastic ParaplegiaSPG47SPG50+8 more
Boston Children's Hospital 700
Large-scale testing (Phase 3)Looking for participantsNCT06692712
What this trial is testing

Phase 3 Efficacy Study With Concurrent Control of IT MELPIDA in SPG50.Concurrent Controls.

Who this might be right for
Hereditary Spastic Paraplegia Type 50
Elpida Therapeutics SPC 24
Early research (Phase 1)Active Not RecruitingNCT06069687
What this trial is testing

Administration of MELPIDA to Determine the Safety and Efficacy for Patients With Spastic Paraplegia Type 50

Who this might be right for
Spastic Paraplegia Type 50
The Hospital for Sick Children 1