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Results for “STAT3”

46 trials

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Showing 20 of 46 results

Testing effectiveness (Phase 2)Study completedNCT03647839
What this trial is testing

Modulation Of The Tumour Microenvironment Using Either Vascular Disrupting Agents or STAT3 Inhibition in Order to Synergise With PD1 Inhibition in Microsatellite Stable, Refractory Colorectal Cancer

Who this might be right for
Colorectal Cancer Metastatic
Australasian Gastro-Intestinal Trials Group 90
Testing effectiveness (Phase 2)Looking for participantsNCT07284641
What this trial is testing

Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)

Who this might be right for
Common Variable Immunodeficiency (CVID)Primary Immune Regulatory DisorderImmune Dysregulation+12 more
Paul Szabolcs 25
Early research (Phase 1)Study completedNCT03527147
What this trial is testing

Platform Study for the Treatment of Relapsed or Refractory Aggressive Non-Hodgkin's Lymphoma (PRISM Study)

Who this might be right for
NHLDLBCLNon-hodgkin's Lymphoma+1 more
Acerta Pharma BV 30
Early research (Phase 1)Looking for participantsNCT07262983
What this trial is testing

Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis

Who this might be right for
Hyper IgE Syndrome From STAT3 MutationJob s SyndromeHIES+2 more
National Institute of Allergy and Infectious Diseases (NIAID) 20
Testing effectiveness (Phase 2)Study completedNCT01563302
What this trial is testing

Phase 1/2, Open-label, Dose-escalation Study of IONIS-STAT3Rx, Administered to Patients With Advanced Cancers

Who this might be right for
Advanced CancersDLBCLLymphoma
Ionis Pharmaceuticals, Inc. 64
Testing effectiveness (Phase 2)Study completedNCT01066663
What this trial is testing

Pyrimethamine for the Treatment of Relapsed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic Leukemia
Dana-Farber Cancer Institute 20
Testing effectiveness (Phase 2)Study completedNCT02629419
What this trial is testing

CAMB/MAT2203 in Patients With Mucocutaneous Candidiasis

Who this might be right for
Candidiasis, Chronic Mucocutaneous
Matinas BioPharma Nanotechnologies, Inc. 4
Not applicableStudy completedNCT01245231
What this trial is testing

Prognostic Biomarkers in Samples From Young Patients With Acute Myeloid Leukemia

Who this might be right for
Leukemia
Children's Oncology Group 150
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06894225
What this trial is testing

Proof-of-Concept Study of ACT001 in Adult Patients With Recurrent Glioblastoma Harbouring STAT3-High Signature

Who this might be right for
Recurrent Glioblastoma
National Neuroscience Institute 12
Not applicableLooking for participantsNCT00006150
What this trial is testing

Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)

Who this might be right for
InfectionsPneumoniaImmune System Diseases+2 more
National Institute of Allergy and Infectious Diseases (NIAID) 600
Early research (Phase 1)Study completedNCT01904123
What this trial is testing

STAT3 Inhibitor WP1066 in Treating Patients With Recurrent Malignant Glioma or Progressive Metastatic Melanoma in the Brain

Who this might be right for
Metastatic Malignant Neoplasm in the BrainMetastatic MelanomaRecurrent Brain Neoplasm+2 more
M.D. Anderson Cancer Center 8
Not applicableEnded earlyNCT01663571
What this trial is testing

STAT3 in T Cells: At The Crossroads of Inflammation and Cancer

Who this might be right for
Cutaneous T Cell Lymphoma
NYU Langone Health 35
Not applicableStudy completedNCT07055256
What this trial is testing

Elucidating the Role of STAT3 in Epithelial-microbiome Interaction During Periodontitis and Peri-implantitis

Who this might be right for
PeriodontitisPeri-implantitis
University of Chile 43
Testing effectiveness (Phase 2)Active Not RecruitingNCT02983578
What this trial is testing

Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal Cancer

Who this might be right for
Advanced Colorectal CarcinomaAdvanced Lung Non-Small Cell CarcinomaLung Non-Small Cell Carcinoma+22 more
M.D. Anderson Cancer Center 39
Early research (Phase 1)Study completedNCT03195699
What this trial is testing

Oral STAT3 Inhibitor, TTI-101, in Patients With Advanced Cancers

Who this might be right for
Breast CancerHead and Neck Squamous Cell CarcinomaNon Small Cell Lung Cancer+5 more
Tvardi Therapeutics, Incorporated 64
Early research (Phase 1)Study completedNCT05440942
What this trial is testing

Combined MEK, STAT3 and PD-1 Inhibition in Metastatic Pancreatic Ductal Adenocarcinoma

Who this might be right for
Pancreatic Ductal Adenocarcinoma
Peter Hosein, MD 28
Early research (Phase 1)Study completedNCT02549651
What this trial is testing

MEDI4736 Alone and in Combination With Tremelimumab or AZD9150 in Adult Subjects With Relapsed/Refractory DLBCL (D4190C00023)

Who this might be right for
Diffuse Large B-Cell Lymphoma
MedImmune LLC 32
Not applicableStudy completedNCT01419496
What this trial is testing

Study of Proteins in Promoting Chemotherapy Resistance in Samples From Patients With Acute Myeloid Leukemia

Who this might be right for
Leukemia
Children's Oncology Group 40
Early research (Phase 1)Study completedNCT01423903
What this trial is testing

Phase 1, Open-label Trial to Determine Safety of OPB-51602 in Subjects With Advanced Cancer

Who this might be right for
Advanced Cancer
Otsuka Pharmaceutical Development & Commercialization, Inc. 45
Large-scale testing (Phase 3)Study completedNCT05480878
What this trial is testing

Role of Nitazoxanide and Escitalopram in Patients With Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Tanta University 90
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