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Results for “STAT3”

46 trials

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Showing 20 of 46 results

Early research (Phase 1)Study completedNCT02549651
What this trial is testing

MEDI4736 Alone and in Combination With Tremelimumab or AZD9150 in Adult Subjects With Relapsed/Refractory DLBCL (D4190C00023)

Who this might be right for
Diffuse Large B-Cell Lymphoma
MedImmune LLC 32
Early research (Phase 1)Study completedNCT00955812
What this trial is testing

STAT3 Inhibitor for Solid Tumors

Who this might be right for
Advanced CancerSolid Tumor
M.D. Anderson Cancer Center 24
Early research (Phase 1)Study completedNCT04702503
What this trial is testing

Study of WP1220 for the Treatment of Adult Subjects With Cutaneous T-Cell Lymphoma (CTCL)

Who this might be right for
Cutaneous T-Cell Lymphoma/Mycosis Fungoides
Moleculin Biotech, Inc. 5
Early research (Phase 1)Study completedNCT01904123
What this trial is testing

STAT3 Inhibitor WP1066 in Treating Patients With Recurrent Malignant Glioma or Progressive Metastatic Melanoma in the Brain

Who this might be right for
Metastatic Malignant Neoplasm in the BrainMetastatic MelanomaRecurrent Brain Neoplasm+2 more
M.D. Anderson Cancer Center 8
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06894225
What this trial is testing

Proof-of-Concept Study of ACT001 in Adult Patients With Recurrent Glioblastoma Harbouring STAT3-High Signature

Who this might be right for
Recurrent Glioblastoma
National Neuroscience Institute 12
Early research (Phase 1)Study completedNCT01839604
What this trial is testing

A Phase I/Ib Study of AZD9150 (ISIS-STAT3Rx) in Patients With Advanced/Metastatic Hepatocellular Carcinoma

Who this might be right for
Advanced Adult Hepatocellular CarcinomaHepatocellular Carcinoma Metastatic
AstraZeneca 58
Early research (Phase 1)Study completedNCT03195699
What this trial is testing

Oral STAT3 Inhibitor, TTI-101, in Patients with Advanced Cancers

Who this might be right for
Breast CancerHead and Neck Squamous Cell CarcinomaNon Small Cell Lung Cancer+5 more
Tvardi Therapeutics, Incorporated 64
Not applicableLooking for participantsNCT00006150
What this trial is testing

Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)

Who this might be right for
InfectionsPneumoniaImmune System Diseases+2 more
National Institute of Allergy and Infectious Diseases (NIAID) 600
Testing effectiveness (Phase 2)Ended earlyNCT02996448
What this trial is testing

Safety, Tolerability, and Immunogenicity of One Dose of NDV 3A Vaccine in People With STAT3-Mutated Hyper-IgE Syndrome

Who this might be right for
Autosomal-dominant Hyper-IgE Syndrome
National Institute of Allergy and Infectious Diseases (NIAID) 3
Early research (Phase 1)Looking for participantsNCT07262983
What this trial is testing

Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis

Who this might be right for
Hyper IgE Syndrome From STAT3 MutationJob s SyndromeHIES+2 more
National Institute of Allergy and Infectious Diseases (NIAID) 20
Not applicableStudy completedNCT04423094
What this trial is testing

Foci of Tumor Heterogeneity in Diffuse Low-Grade Gliomas

Who this might be right for
Glioma
University Hospital, Montpellier 8
Not applicableStudy completedNCT01419496
What this trial is testing

Study of Proteins in Promoting Chemotherapy Resistance in Samples From Patients With Acute Myeloid Leukemia

Who this might be right for
Leukemia
Children's Oncology Group 40
Large-scale testing (Phase 3)Study completedNCT05480878
What this trial is testing

Role of Nitazoxanide and Escitalopram in Patients With Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Tanta University 90
Early research (Phase 1)Active Not RecruitingNCT06188208
What this trial is testing

A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130850 in Participants With Advanced Solid and Hematologic Tumors

Who this might be right for
Advanced Solid TumorsAdvanced Hematologic Tumors
Vividion Therapeutics, Inc. 125
Early research (Phase 1)Ended earlyNCT02058017
What this trial is testing

OPB-51602 in Locally Advanced Nasopharyngeal Carcinoma Prior to Definitive Chemoradiotherapy

Who this might be right for
Nasopharyngeal Carcinoma
National University Hospital, Singapore 9
Early research (Phase 1)WithdrawnNCT03057990
What this trial is testing

Pyrimethamine for Intermediate/High-risk Myelodysplastic Syndromes (MDS)

Who this might be right for
Myelodysplastic Syndromes
Montefiore Medical Center
Early research (Phase 1)WithdrawnNCT04995536
What this trial is testing

CpG-STAT3 siRNA CAS3/SS3 and Localized Radiation Therapy for the Treatment of Relapsed/Refractory B-Cell NHL

Who this might be right for
Recurrent B-Cell Non-Hodgkin LymphomaRecurrent Diffuse Large B-Cell LymphomaRecurrent Grade 1 Follicular Lymphoma+17 more
City of Hope Medical Center
Not applicableStudy completedNCT01245231
What this trial is testing

Prognostic Biomarkers in Samples From Young Patients With Acute Myeloid Leukemia

Who this might be right for
Leukemia
Children's Oncology Group 150
Early research (Phase 1)Study completedNCT01423903
What this trial is testing

Phase 1, Open-label Trial to Determine Safety of OPB-51602 in Subjects With Advanced Cancer

Who this might be right for
Advanced Cancer
Otsuka Pharmaceutical Development & Commercialization, Inc. 45
Testing effectiveness (Phase 2)Ended earlyNCT02417753
What this trial is testing

AZD9150, a STAT3 Antisense Oligonucleotide, in People With Malignant Ascites

Who this might be right for
Ovarian CancerOvarian NeoplasmsAscites+2 more
National Cancer Institute (NCI) 1
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