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Results for “STAT3”

46 trials

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Showing 20 of 46 results

Early research (Phase 1)Study completedNCT01423903
What this trial is testing

Phase 1, Open-label Trial to Determine Safety of OPB-51602 in Subjects With Advanced Cancer

Who this might be right for
Advanced Cancer
Otsuka Pharmaceutical Development & Commercialization, Inc. 45
Early research (Phase 1)Study completedNCT03195699
What this trial is testing

Oral STAT3 Inhibitor, TTI-101, in Patients With Advanced Cancers

Who this might be right for
Breast CancerHead and Neck Squamous Cell CarcinomaNon Small Cell Lung Cancer+5 more
Tvardi Therapeutics, Incorporated 64
Early research (Phase 1)Study completedNCT00955812
What this trial is testing

STAT3 Inhibitor for Solid Tumors

Who this might be right for
Advanced CancerSolid Tumor
M.D. Anderson Cancer Center 24
Not applicableStudy completedNCT01057290
What this trial is testing

Studying Biomarkers in Cell Samples From Young Patients With Acute Myeloid Leukemia

Who this might be right for
Leukemia
Children's Oncology Group 75
Not applicableStudy completedNCT05506098
What this trial is testing

Investigating STAT3 as a Driver of Pathology in Periodontitis

Who this might be right for
Periodontitis
University of Chile 28
Not applicableLooking for participantsNCT00001467
What this trial is testing

Genetic Analysis of Immune Disorders

Who this might be right for
DOK 8STAT1GATA2+2 more
National Institute of Allergy and Infectious Diseases (NIAID) 5,000
Testing effectiveness (Phase 2)Ended earlyNCT02996448
What this trial is testing

Safety, Tolerability, and Immunogenicity of One Dose of NDV 3A Vaccine in People With STAT3-Mutated Hyper-IgE Syndrome

Who this might be right for
Autosomal-dominant Hyper-IgE Syndrome
National Institute of Allergy and Infectious Diseases (NIAID) 3
Testing effectiveness (Phase 2)Active Not RecruitingNCT02983578
What this trial is testing

Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal Cancer

Who this might be right for
Advanced Colorectal CarcinomaAdvanced Lung Non-Small Cell CarcinomaLung Non-Small Cell Carcinoma+22 more
M.D. Anderson Cancer Center 39
Early research (Phase 1)Ended earlyNCT05384119
What this trial is testing

Phase 1b/2 Study of TTI-101 in Combination for Patients With Metastatic Hormone Receptor-Positive and HER2-Negative Breast Cancer

Who this might be right for
Breast Cancer
Tvardi Therapeutics, Incorporated 6
Early research (Phase 1)Study completedNCT02549651
What this trial is testing

MEDI4736 Alone and in Combination With Tremelimumab or AZD9150 in Adult Subjects With Relapsed/Refractory DLBCL (D4190C00023)

Who this might be right for
Diffuse Large B-Cell Lymphoma
MedImmune LLC 32
Early research (Phase 1)WithdrawnNCT04995536
What this trial is testing

CpG-STAT3 siRNA CAS3/SS3 and Localized Radiation Therapy for the Treatment of Relapsed/Refractory B-Cell NHL

Who this might be right for
Recurrent B-Cell Non-Hodgkin LymphomaRecurrent Diffuse Large B-Cell LymphomaRecurrent Grade 1 Follicular Lymphoma+17 more
City of Hope Medical Center
Early research (Phase 1)Ended earlyNCT06188208
What this trial is testing

A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130850 in Participants With Advanced Solid and Hematologic Tumors

Who this might be right for
Advanced Solid TumorsAdvanced Hematologic Tumors
Vividion Therapeutics, Inc. 132
Not applicableStudy completedNCT07055256
What this trial is testing

Elucidating the Role of STAT3 in Epithelial-microbiome Interaction During Periodontitis and Peri-implantitis

Who this might be right for
PeriodontitisPeri-implantitis
University of Chile 43
Not applicableUnknownNCT02967419
What this trial is testing

The Study of the Relationship Between TWEAK/Fn14, JAK/STAT3 and IDO in the Immune Microenvironment of Endometrium in Repeated Implantation Failure

Who this might be right for
Repeated Implantation Failure
ZhangTao 60
Very early researchStudy completedNCT00696176
What this trial is testing

STAT3 DECOY in Head and Neck Cancer

Who this might be right for
Head and Neck Cancer
University of Pittsburgh 32
Early research (Phase 1)Ended earlyNCT02058017
What this trial is testing

OPB-51602 in Locally Advanced Nasopharyngeal Carcinoma Prior to Definitive Chemoradiotherapy

Who this might be right for
Nasopharyngeal Carcinoma
National University Hospital, Singapore 9
Testing effectiveness (Phase 2)Temporarily pausedNCT06894225
What this trial is testing

Proof-of-Concept Study of ACT001 in Adult Patients With Recurrent Glioblastoma Harbouring STAT3-High Signature

Who this might be right for
Recurrent Glioblastoma
National Neuroscience Institute 12
Not applicableStudy completedNCT03203486
What this trial is testing

Response of NAFLD Patients to Mediterranean Diet

Who this might be right for
NAFLDSteatosis of Liver
Harokopio University 44
Very early researchStudy completedNCT01568996
What this trial is testing

Pilot Study Evaluating Sulforaphane in Atypical Nevi-Precursor Lesions

Who this might be right for
Atypical NeviMelanoma
John Kirkwood 17
Large-scale testing (Phase 3)Study completedNCT05480878
What this trial is testing

Role of Nitazoxanide and Escitalopram in Patients With Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Tanta University 90
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