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Results for “Sclerosis, Progressive Systemic”

95 trials

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Showing 20 of 95 results

Testing effectiveness (Phase 2)Ended earlyNCT04680975
What this trial is testing

Efficacy and Safety of Belumosudil in Subjects With Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Diffuse Cutaneous Systemic Sclerosis
Kadmon, a Sanofi Company 10
Early research (Phase 1)Study completedNCT03831438
What this trial is testing

Safety and Tolerability Study of AVID200 in Pts With Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Scleroderma, Diffuse
Bristol-Myers Squibb 9
Testing effectiveness (Phase 2)Ended earlyNCT04781543
What this trial is testing

Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients With Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Diffuse Cutaneous Systemic SclerosisSclerosis, Systemic
Amgen 301
Early research (Phase 1)Looking for participantsNCT06414135
What this trial is testing

Relmacabtagene Autoleucel for the Treatment of Systemic Sclerosis

Who this might be right for
Systemic Sclerosis
Liangjing Lu 6
Testing effectiveness (Phase 2)Study completedNCT01538719
What this trial is testing

IL1-TRAP, Rilonacept, in Systemic Sclerosis

Who this might be right for
SclerodermaSystemic SclerosisDiffuse Scleroderma+1 more
Boston University 24
Testing effectiveness (Phase 2)Study completedNCT00004380
What this trial is testing

Phase II Study of Recombinant Relaxin for Progressive Systemic Sclerosis

Who this might be right for
Systemic Sclerosis
National Center for Research Resources (NCRR) 1
Testing effectiveness (Phase 2)Ended earlyNCT02465437
What this trial is testing

Safety, Tolerability, Efficacy, and Pharmacokinetics of JBT-101 in Systemic Sclerosis

Who this might be right for
Diffuse Cutaneous Systemic Sclerosis
Corbus Pharmaceuticals Inc. 42
Testing effectiveness (Phase 2)Ended earlyNCT05626751
What this trial is testing

An Open-label Extension Trial of HZNP-HZN-825-301 in Adult Participants With Diffuse Cutaneous Systemic Sclerosis (Diffuse Cutaneous SSc)

Who this might be right for
Diffuse Cutaneous Systemic SclerosisSclerosis, Systemic
Amgen 174
Testing effectiveness (Phase 2)UnknownNCT00769028
What this trial is testing

AIMSPRO in Established Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Systemic Sclerosis
Daval International Limited 20
Testing effectiveness (Phase 2)Ended earlyNCT04837131
What this trial is testing

Evaluate the Safety and Tolerability of Oral Ixazomib in Scleroderma-related Lung Disease Patients

Who this might be right for
Systemic SclerosisSclerodermaDiffuse Systemic Sclerosis+16 more
Michael M. Pham 4
Testing effectiveness (Phase 2)Study completedNCT05559580
What this trial is testing

A Study in People With Systemic Sclerosis to Test Whether Avenciguat (BI 685509) Has an Effect on Lung Function and Other Systemic Sclerosis Symptoms

Who this might be right for
Scleroderma, Systemic
Boehringer Ingelheim 214
Early research (Phase 1)Active Not RecruitingNCT06255028
What this trial is testing

CNTY-101 in Participants With Refractory B Cell-mediated Autoimmune Diseases

Who this might be right for
Systemic Lupus ErythematosusLupus NephritisIdiopathic Inflammatory Myopathies+1 more
Century Therapeutics, Inc. 6
Testing effectiveness (Phase 2)WithdrawnNCT05098145
What this trial is testing

A Safety and Efficacy Study of FCR001 in Adults With Rapidly Progressive Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Diffuse Cutaneous Systemic Sclerosis
Talaris Therapeutics Inc.
Large-scale testing (Phase 3)Looking for participantsNCT06936215
What this trial is testing

Safety and Efficacy of Baricitinib on Skin Tightening in Diffuse Cutaneous Systemic Sclerosis: A Comparative Study With Methotrexate

Who this might be right for
Diffuse Cutaneous Systemic Sclerosis
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 24
Post-approval studies (Phase 4)Study completedNCT07472166
What this trial is testing

Efficacy of Tofacitinib on Skin Thickening in Diffuse Cutaneous Systemic Sclerosis: A Comparative Study With Methotrexate

Who this might be right for
Scleroderma, Systemic
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 34
Large-scale testing (Phase 3)UnknownNCT00428883
What this trial is testing

High Dose Intravenous N-Acetylcysteine Versus Iloprost for Early, Rapidly Progressive Diffuse Systemic Sclerosis

Who this might be right for
Scleroderma, Diffuse
Università Politecnica delle Marche 45
Early research (Phase 1)Looking for participantsNCT06925542
What this trial is testing

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

Who this might be right for
SLE (Systemic Lupus)Lupus Erythematosus, SystemicLupus Nephritis+4 more
CRISPR Therapeutics 80
Early research (Phase 1)Study completedNCT00433186
What this trial is testing

Mycophenolate Mofetil in Systemic Sclerosis

Who this might be right for
Diffuse Cutaneous Systemic Sclerosis
Boston University 30
Testing effectiveness (Phase 2)Study completedNCT02161406
What this trial is testing

Subcutaneous Abatacept to Treat Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Diffuse Cutaneous Systemic Sclerosis
Dinesh Khanna, MD, MS 88
Testing effectiveness (Phase 2)WithdrawnNCT04138485
What this trial is testing

Efficacy and Safety of IgPro10 in Adults With Systemic Sclerosis (SSc)

Who this might be right for
Diffuse Cutaneous Systemic Sclerosis
CSL Behring
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