Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Second Primary Squamous Cell Carcinoma of the Head and Neck”

22 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 22 results

Testing effectiveness (Phase 2)Ended earlyNCT04220775
What this trial is testing

Bintrafusp Alfa and Stereotactic Body Radiation Therapy for the Treatment of Recurrent or Second Primary Head and Neck Squamous Cell Cancer

Who this might be right for
Recurrent Head and Neck Squamous Cell CarcinomaSecond Primary Squamous Cell Carcinoma of the Head and Neck
M.D. Anderson Cancer Center 3
Testing effectiveness (Phase 2)Ended earlyNCT00573989
What this trial is testing

Intensity-Modulated Radiation Therapy, Pemetrexed, and Erlotinib in Treating Patients With Recurrent or Second Primary Head and Neck Cancer

Who this might be right for
Head and Neck Cancer
Wake Forest University Health Sciences 27
Early research (Phase 1)Study completedNCT00400374
What this trial is testing

Secondary Primary Tumor Prevention With EGFR, OSI-774, and Cyclooxygenase-2

Who this might be right for
Head and Neck Cancer
Emory University 10
Testing effectiveness (Phase 2)Study completedNCT02289209
What this trial is testing

Reirradiation With Pembrolizumab in Locoregional Inoperable Recurrence or Second Primary Squamous Cell CA of the Head and Neck

Who this might be right for
Recurrent Head and Neck CancerCarcinoma, Squamous Cell of Head and Neck
Dan Zandberg 48
Not applicableUnknownNCT03917524
What this trial is testing

Feasibility of CTCs Isolation for Transcriptomes and Genome Wide Associated Analysis in Post-OP High Risk OSCC Patients.

Who this might be right for
Oral Cavity Squamous Cell Carcinoma
Chang Gung Memorial Hospital 180
Testing effectiveness (Phase 2)Active Not RecruitingNCT03546582
What this trial is testing

SBRT +/- Pembrolizumab in Patients With Local-Regionally Recurrent or Second Primary Head and Neck Carcinoma

Who this might be right for
Head and Neck Squamous Cell Carcinoma (HNSCC)
RTOG Foundation, Inc. 86
Early research (Phase 1)Study completedNCT02544880
What this trial is testing

PDE5 Inhibition Via Tadalafil to Enhance Anti-Tumor Mucin 1 (MUC1) Vaccine Efficacy in Patients With HNSCC

Who this might be right for
Head and Neck Squamous Cell CarcinomaHead and Neck Cancer
Donald T. Weed, MD, FACS 16
Not applicableStudy completedNCT00415025
What this trial is testing

Side Effects of High-Dose Intensity-Modulated Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer

Who this might be right for
Head and Neck CancerLong-term Effects Secondary to Cancer Therapy in AdultsOral Complications of Radiation Therapy+1 more
University of Wisconsin, Madison 20
Not applicableStudy completedNCT01783158
What this trial is testing

Chromoendoscopy to Detect Early Synchronous Second Primary Esophageal Carcinoma

Who this might be right for
Squamous Cell Carcinomas of the Head and Neck
University Hospital Ostrava 132
Testing effectiveness (Phase 2)Study completedNCT03521570
What this trial is testing

Intensity-Modulated Radiation Therapy & Nivolumab for Recurrent or Second Primary Head & Neck Squamous Cell Cancer

Who this might be right for
Recurrent Head and Neck Squamous Cell Carcinoma
Emory University 62
Large-scale testing (Phase 3)Ended earlyNCT00198328
What this trial is testing

Medpulser Electroporation With Bleomycin Study to Treat Posterior Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head Neck Cancer
Inovio Pharmaceuticals 84
Large-scale testing (Phase 3)Ended earlyNCT00198315
What this trial is testing

Medpulser Electroporation With Bleomycin Study to Treat Anterior Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Cancer
Inovio Pharmaceuticals 130
Testing effectiveness (Phase 2)UnknownNCT00003856
What this trial is testing

Photodynamic Therapy in Treating Patients With Recurrent, Refractory, or Second Primary Head and Neck Cancer That Cannot Be Treated With Surgery or Radiation Therapy

Who this might be right for
Head and Neck Cancer
Quintiles, Inc. 75
Not applicableStudy completedNCT00828516
What this trial is testing

Using Traditional Acupuncture in the Management of Cancer Treatment Related Lymphoedema

Who this might be right for
Breast CancerHead and Neck CancerLymphedema
East and North Hertfordshire NHS Trust 56
Early research (Phase 1)Study completedNCT00036790
What this trial is testing

Motexafin Gadolinium and Doxorubicin in Treating Patients With Advanced Cancer

Who this might be right for
Breast CancerChronic Myeloproliferative DisordersColorectal Cancer+9 more
University of Wisconsin, Madison
Testing effectiveness (Phase 2)UnknownNCT00004226
What this trial is testing

Radiation Therapy Following Surgery in Treating Patients With Recurrent or Second Primary Cancer of the Head and Neck Following Previous Radiation Therapy

Who this might be right for
Head and Neck Cancer
University of Alabama at Birmingham
Large-scale testing (Phase 3)Study completedNCT00538850
What this trial is testing

Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain

Who this might be right for
Cancer
INSYS Therapeutics Inc 130
Early research (Phase 1)Ended earlyNCT02110992
What this trial is testing

Safety Study of SBRT and Docetaxel for Locally Recurrent or Second Primary Squamous Cell Carcinoma of the Head and Neck

Who this might be right for
Head and Neck Cancer
University of Cincinnati 7
Large-scale testing (Phase 3)Study completedNCT00017511
What this trial is testing

Cevimeline in Treating Patients With Dry Mouth Caused by Radiation Therapy for Head and Neck Cancer

Who this might be right for
Head and Neck CancerOral ComplicationsRadiation Toxicity
Daiichi Sankyo
Testing effectiveness (Phase 2)Looking for participantsNCT05726370
What this trial is testing

Preoperative Pembrolizumab and Chemotherapy in Resectable, Recurrent HNSCC

Who this might be right for
Head and Neck Squamous Cell CarcinomaHead and Neck CancerResectable Head and Neck Squamous Cell Carcinoma+2 more
Dana-Farber Cancer Institute 28
Load More Results