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Results for “Secondary Hemophagocytic Lymphohistiocytosis”

14 trials

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Showing 14 of 14 results

Not applicableUnknownNCT04347460
What this trial is testing

Establishing a COVID-19 Prospective Cohort for Identification of Secondary HLH

Who this might be right for
COVID
Technical University of Munich 20
Large-scale testing (Phase 3)Study completedNCT04979884
What this trial is testing

Safety and Effectiveness of Cyclosporin in the Management of COVID19 ARDS Patients in Alexandria University Hospital

Who this might be right for
COVID-19 Acute Respiratory Distress SyndromeCytokine Release SyndromePulmonary Fibrosis
Alexandria University 66
Large-scale testing (Phase 3)Study completedNCT05001737
What this trial is testing

Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE

Who this might be right for
Macrophage Activation SyndromeSecondary Hemophagocytic LymphohistiocytosisStill Disease+4 more
Swedish Orphan Biovitrum 33
Not applicableStudy completedNCT07531069
What this trial is testing

Efficacy and Safety of Interferon-Gamma Monoclonal Antibody Combined With Dexamethasone in the Treatment of Refractory Adult Secondary Hemophagocytic Lymphohistiocytosis

Who this might be right for
Adult Refractory Secondary Hemophagocytic LymphohistiocytosisSecondary Hemophagocytic LymphohistiocytosisHLH
Fudan University 22
Not applicableStudy completedNCT01125319
What this trial is testing

Secondary Adult's Hemophagocytic Lymphohistiocytosis and Innate Immunity

Who this might be right for
Hemophagocytic Lymphohisticytosis
Assistance Publique Hopitaux De Marseille 120
Not applicableUnknownNCT05841342
What this trial is testing

Prospective Study of Immune Function and PD-1 Antibody Therapy Efficacy Predictors on CAEBV and EBV-HLH Patients

Who this might be right for
Secondary Hemophagocytic LymphohistiocytosisChronic Active Epstein-Barr Virus Infection
Beijing Friendship Hospital 128
Not applicableLooking for participantsNCT06339177
What this trial is testing

Hemophagocytic Lymphohistiocytosis (HLH) Evaluation and Research of Clinical, ImmUnoLogic and TranscriptomE Study

Who this might be right for
Lymphohistiocytosis, HemophagocyticSecondary Hemophagocytic LymphohistiocytosisMacrophage Activation Syndrome+1 more
National Institute of Allergy and Infectious Diseases (NIAID) 300
Post-approval studies (Phase 4)Looking for participantsNCT07270835
What this trial is testing

Zanubrutinib Combined With Rituximab in the Treatment of Secondary HLH in B-cell Lymphoma

Who this might be right for
Hemophagocytic LymphohistiocytosisB Cell Lymphoma
The First Affiliated Hospital of Soochow University 40
Testing effectiveness (Phase 2)Study completedNCT03311854
What this trial is testing

Investigate the Safety and Efficacy of Emapalumab, an Anti-IFN-gamma mAb in Patients With Systemic Juvenile Idiopathic Arthritis (sJIA) or Adult-onset Still's Disease (AOSD) Developing Macrophage Activation Syndrome/Secondary HLH (MAS/sHLH)

Who this might be right for
Macrophage Activation SyndromeLymphohistiocytosis, HemophagocyticArthritis, Juvenile+1 more
Swedish Orphan Biovitrum 14
Testing effectiveness (Phase 2)Study completedNCT02400463
What this trial is testing

A Pilot Study of Ruxolitinib in Secondary Hemophagocytic Syndrome

Who this might be right for
Hemophagocytic Syndrome (HPS)
University of Michigan Rogel Cancer Center 6
Large-scale testing (Phase 3)UnknownNCT05384743
What this trial is testing

Rituximab Monotherapy for EBV-HLH and CAEBV

Who this might be right for
Secondary Hemophagocytic LymphohistiocytosisChronic Active Epstein-Barr Virus Infection
Beijing Friendship Hospital 30
Testing effectiveness (Phase 2)UnknownNCT03795909
What this trial is testing

Ruxolitinib Combined With Dexamethasone for HLH

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Capital Research Institute of Pediatrics 50
Large-scale testing (Phase 3)Looking for participantsNCT05416307
What this trial is testing

Open-label Study of ELA026 in Participants With Secondary Hemophagocytic Lymphohistiocytosis (sHLH)

Who this might be right for
Secondary Hemophagocytic Lymphohistiocytosis (sHLH)
Electra Therapeutics Inc. 156
Not applicableEnded earlyNCT01547143
What this trial is testing

Pilot Study of Etoposide-based Therapy and Hematopoietic Cell Transplantation for Hemophagocytic Lymphohistiocytosis

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Asan Medical Center 12