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Results for “Secondary Progressive MS (SPMS)”

23 trials

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Showing 20 of 23 results

Post-approval studies (Phase 4)Study completedNCT04792567
What this trial is testing

Exploring the Immune Response to SARS-CoV-2 modRNA Vaccines in Patients With Secondary Progressive Multiple Sclerosis (AMA-VACC)

Who this might be right for
Secondary Progressive Multiple Sclerosis
Novartis Pharmaceuticals 41
Not applicableLooking for participantsNCT05177523
What this trial is testing

Imaging the Interplay Between Axonal Damage and Repair in Multiple Sclerosis

Who this might be right for
Multiple Sclerosis (MS)Relapsing-remitting Multiple Sclerosis (RRMS)Secondary-progressive Multiple Sclerosis (SPMS)+1 more
University Hospital, Basel, Switzerland 300
Large-scale testing (Phase 3)Study completedNCT04353492
What this trial is testing

An Open-label Study Evaluating Ofatumumab Treatment Effectiveness and PROs in Subjects With RMS Transitioning From Fumarate-based RMS Approved Therapies or Fingolimod to Ofatumumab

Who this might be right for
Relapsing Multiple Sclerosis
Novartis Pharmaceuticals 562
Testing effectiveness (Phase 2)Looking for participantsNCT07477639
What this trial is testing

Treatment of Participants With Primary or Secondary Progressive Multiple Sclerosis

Who this might be right for
Primary Progressive Multiple SclerosisSecondary Progressive Multiple Sclerosis (SPMS)Multiple Sclerosis+2 more
Tr1X, Inc. 39
Large-scale testing (Phase 3)UnknownNCT02220244
What this trial is testing

Effect of MD1003 in Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
MedDay Pharmaceuticals SA 105
Not applicableStudy completedNCT01080014
What this trial is testing

Correlation Between Multiple Sclerosis Functional Composite (MSFC) and Expanded Disability Status Scale (EDSS) in Patients With Multiple Sclerosis (MS) in Argentina

Who this might be right for
Multiple Sclerosis
Merck KGaA, Darmstadt, Germany 252
Not applicableStudy completedNCT03408093
What this trial is testing

Study of Betaferon Adherence in Patients With Multiple Sclerosis Treated With Interferon Beta-1b

Who this might be right for
Multiple Sclerosis
Bayer 120
Large-scale testing (Phase 3)Looking for participantsNCT07225504
What this trial is testing

Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis

Who this might be right for
Secondary Progressive Multiple Sclerosis (SPMS)
Novartis Pharmaceuticals 1,275
Not applicableStudy completedNCT01804647
What this trial is testing

Longitudinal Therapeutically Non-interventional Study of MSRV-Env Burden in Patients With Multiple Sclerosis Disease

Who this might be right for
Multiple Sclerosis (MS)Relapsing-Remitting MSPrimary Progressive MS+2 more
GeNeuro Innovation SAS 58
Large-scale testing (Phase 3)Ended earlyNCT01416181
What this trial is testing

A Clinical Study of the Efficacy of Natalizumab on Reducing Disability Progression in Participants With Secondary Progressive Multiple Sclerosis

Who this might be right for
Secondary Progressive Multiple Sclerosis
Biogen 889
Large-scale testing (Phase 3)Active Not RecruitingNCT05156281
What this trial is testing

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS) (REMODEL-2)

Who this might be right for
Relapsing Multiple Sclerosis
Novartis Pharmaceuticals 1,007
Large-scale testing (Phase 3)Active Not RecruitingNCT05147220
What this trial is testing

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS) (REMODEL-1)

Who this might be right for
Relapsing Multiple Sclerosis
Novartis Pharmaceuticals 1,000
Testing effectiveness (Phase 2)Study completedNCT01191996
What this trial is testing

Safety Study of an Immunomodulating Microparticle to Treat Progressive Multiple Sclerosis

Who this might be right for
Secondary Progressive Multiple SclerosisPrimary Progressive Multiple Sclerosis
Innate Immunotherapeutics 34
Early research (Phase 1)Looking for participantsNCT06680037
What this trial is testing

Assess the Safety and Clinical Activity of Azer-cel in Participants With B-cell Mediated Autoimmune Disorders

Who this might be right for
B-cell Mediated Autoimmune Disorders
TG Therapeutics, Inc. 100
Early research (Phase 1)Ended earlyNCT01144351
What this trial is testing

A Safety and Efficacy Study of ELND002 in Patients With Relapsing Forms of Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
Elan Pharmaceuticals 32
Not applicableStudy completedNCT01233245
What this trial is testing

BetaPlus Survey - Observational Study to Assess Drug Adherence in Patients With Multiple Sclerosis After Conversion to Betaferon® by Using Elements of the BetaPlus Program

Who this might be right for
Relapsing Remitting MS (RRMS)Secondary Progressive MS (SPMS)
Bayer 1,077
Not applicableStudy completedNCT01235455
What this trial is testing

Portuguese Observational Survey to Assess Drug Adherence in Patients With Multiple Sclerosis After Conversion to Betaferon by Using Elements of the BetaPlus Program - Nurse Support, Auto-injectors

Who this might be right for
Relapsing Remitting Multiple Sclerosis (RRMS)Secondary Progressive Multiple Sclerosis (SPMS)
Bayer 10
Large-scale testing (Phase 3)Temporarily pausedNCT05441488
What this trial is testing

Masitinib in the Treatment of Patients With Primary Progressive or Non-active Secondary Progressive Multiple Sclerosis

Who this might be right for
Progressive Multiple Sclerosis
AB Science 800
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07765212
What this trial is testing

Evaluating the Use of Oral Indapamide to Reduce Disabiltiy Progression in Progressive Multiple Sclerosis (MS)

Who this might be right for
Multiple Sclerosis
Eva M.M. Strijbis 75
Early research (Phase 1)Temporarily pausedNCT06677710
What this trial is testing

IDP-023 g-NK Cells Plus Ocrelizumab in Patients With Progressive Multiple Sclerosis

Who this might be right for
Multiple SclerosisPrimary Progressive Multiple Sclerosis (PPMS)Secondary Progressive Multiple Sclerosis (SPMS)+8 more
Indapta Therapeutics, INC. 34
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