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Results for “Secondary to Immune Checkpoint Inhibitors”

64 trials

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Showing 20 of 64 results

Large-scale testing (Phase 3)Looking for participantsNCT06581406
What this trial is testing

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

Who this might be right for
Metastatic Uveal Melanoma
Replimune, Inc. 280
Early research (Phase 1)Ended earlyNCT04628780
What this trial is testing

Study to Test the Safety and Tolerability of PF-07209960 in Advanced or Metastatic Solid Tumors

Who this might be right for
Non-small-cell Lung CancerSquamous Cell Carcinoma of the Head and NeckRenal Cell Carcinoma+3 more
Pfizer 37
Testing effectiveness (Phase 2)Looking for participantsNCT07130032
What this trial is testing

Efficacy And Safety Of Anti-PD-1/PD-L1 Antibodies In Combination With Bevacizumab And Metronomic Cyclophosphamide In Patients With Non-Small Cell Lung Cancer And Cutaneous Melanoma Previously Treated With Immune Checkpoint Blockade

Who this might be right for
Metastatic Non-small Cell Lung Cancer (NSCLC)Metastatic Cutaneous Melanoma
EuroCityClinic LLC 90
Testing effectiveness (Phase 2)Active Not RecruitingNCT05205330
What this trial is testing

Vorbipiprant (CR6086) / Balstilimab (AGEN2034) Combination in Stage IV Refractory pMMR - MSS CRC, and Other Metastatic GI Cancers

Who this might be right for
Refractory Metastatic Colorectal CancerSolid TumorMetastatic Microsatellite-stable Colorectal Cancer+3 more
Rottapharm Biotech 107
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06602063
What this trial is testing

Surgery for Relapsed Ovarian Cancer in Precision

Who this might be right for
Epithelial Ovarian CancerFallopian Tube CancerPrimary Peritoneal Carcinoma
Shanghai Gynecologic Oncology Group 33
Large-scale testing (Phase 3)Ended earlyNCT04338269
What this trial is testing

Atezolizumab in Combination With Cabozantinib Compared to Cabozantinib Alone in Participants With Advanced Renal Cell Carcinoma After Immune Checkpoint Inhibitor Treatment

Who this might be right for
Carcinoma, Renal Cell
Hoffmann-La Roche 522
Testing effectiveness (Phase 2)Ended earlyNCT05935748
What this trial is testing

Ph2 Study NKT2152 With Palbociclib & Sasanlimab in Subjects With Advanced Clear Cell Renal Cell Carcinoma (ccRcc)

Who this might be right for
ccRCCClear Cell Renal Cell CarcinomaKidney Cancer+18 more
NiKang Therapeutics, Inc. 18
Not applicableLooking for participantsNCT07223411
What this trial is testing

Opdualag vs. Cemiplimab/Fianlimab in Relation to the Immunological Response in Tumor and Peripheral Blood in Unresectable or Metastatic Melanoma

Who this might be right for
Locally Advanced Melanoma
John Kirkwood 20
Large-scale testing (Phase 3)Active Not RecruitingNCT04590963
What this trial is testing

Assessment of Efficacy and Safety of Monalizumab Plus Cetuximab Compared to Placebo Plus Cetuximab in Recurrent or Metastatic Head and Neck Cancer

Who this might be right for
Squamous Cell Carcinoma of the Head and Neck
AstraZeneca 370
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06478043
What this trial is testing

Investigate the Efficacy and Safety of Ivonescimab Combined With Irinotecan Liposome as Second-line Regimen for ES-SCLC

Who this might be right for
Extensive-stage Small-cell Lung Cancer
Zhejiang Cancer Hospital 54
Large-scale testing (Phase 3)Looking for participantsNCT06346197
What this trial is testing

Combination of Immune Checkpoint in Locally Advanced or Metastatic MSI/dMMR Esogastric Adenocarcinomas

Who this might be right for
Gastric CancerMSI-HMetastatic Cancer+1 more
Centre Leon Berard 132
Not applicableLooking for participantsNCT06227728
What this trial is testing

Analysis of PD-L1, TMB, MSI and ctDNA Dynamics to Predict and Monitor Response to Immunotherapy in Metastatic Cancer.

Who this might be right for
Non Small Cell Lung CancerBreast CancerColorectal Cancer+4 more
Gene Solutions 50
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07487519
What this trial is testing

Phase II Study of HLX43 Monotherapy or Combined With Immune Checkpoint Inhibitors in Patients With Locally Advanced, Recurrent, or Metastatic Triple-negative Breast Cancer.

Who this might be right for
Breast Cancer (Triple Negative Breast Cancer (TNBC))
Shanghai Henlius Biotech 180
Early research (Phase 1)Looking for participantsNCT06270706
What this trial is testing

PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid Tumor
Pliant Therapeutics, Inc. 124
Not applicableLooking for participantsNCT06470997
What this trial is testing

Specific Biomarkers of Immune-mediated Hepatitis Secondary to Immune Checkpoint Inhibitors

Who this might be right for
Immune-mediated Hepatitis
University Hospital, Montpellier 60
Not applicableStudy completedNCT03035890
What this trial is testing

Hypofractionated Radiation Therapy to Improve Immunotherapy Response in Non-Small Cell Lung Cancer

Who this might be right for
Non Small Cell Lung Cancer Metastatic
West Virginia University 35
Testing effectiveness (Phase 2)Looking for participantsNCT06917092
What this trial is testing

QL1706-Based Therapy Post-PD-1/L1 Failure in Advanced Endometrial Cancer

Who this might be right for
Endometrial AdenocarcinomaEndometrial Cancer
Tianjin Medical University Cancer Institute and Hospital 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT04706715
What this trial is testing

LAG3 PET Imaging in Advanced Solid Tumors

Who this might be right for
Metastatic Solid Tumor
University Medical Center Groningen 41
Testing effectiveness (Phase 2)UnknownNCT06172634
What this trial is testing

A Single-center Clinical Study to Evaluate the Safety and Efficacy of Autologous Bone Marrow-derived DCs(CellgramDC-WT1) and Immune Checkpoint Inhibitors in Patients With Metastatic Pancreatic Cancer Who Have Failed First-line or More Standard Chemotherapy

Who this might be right for
Pancreas Cancer
Soonchunhyang University Hospital 10
Early research (Phase 1)Active Not RecruitingNCT05334329
What this trial is testing

Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab for the Treatment of Non-small Cell Lung Cancer Previously Treated With PD-1 and/or PD-L1 Immune Checkpoint Inhibitors

Who this might be right for
Advanced Lung Non-Small Cell CarcinomaMetastatic Lung Non-Small Cell CarcinomaRecurrent Lung Non-Small Cell Carcinoma+8 more
University of California, Irvine 6
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