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Results for “Secondary to Immune Checkpoint Inhibitors”

67 trials

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Showing 20 of 67 results

Not applicableActive Not RecruitingNCT05478538
What this trial is testing

Observational Lung Trial to Collect Tissue to Train and Validate a Live Tumor Diagnostic Platform (ELEPHAS-01)

Who this might be right for
NSCLC (Non-small Cell Lung Cancer)Metastatic NSCLC - Non-Small Cell Lung Cancer
Elephas 200
Not applicableLooking for participantsNCT06227728
What this trial is testing

Analysis of PD-L1, TMB, MSI and ctDNA Dynamics to Predict and Monitor Response to Immunotherapy in Metastatic Cancer.

Who this might be right for
Non Small Cell Lung CancerBreast CancerColorectal Cancer+4 more
Gene Solutions 50
Not applicableLooking for participantsNCT07223411
What this trial is testing

Opdualag vs. Cemiplimab/Fianlimab in Relation to the Immunological Response in Tumor and Peripheral Blood in Unresectable or Metastatic Melanoma

Who this might be right for
Locally Advanced Melanoma
John Kirkwood 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT05822752
What this trial is testing

Study to Evaluate Adverse Events, and Change in Disease Activity, When Intravenously (IV) Infused With Livmoniplimab in Combination With IV Infused Budigalimab in Adult Participants With Hepatocellular Carcinoma (HCC)

Who this might be right for
Hepatocellular Carcinoma
AbbVie 130
Large-scale testing (Phase 3)Looking for participantsNCT06346197
What this trial is testing

Combination of Immune Checkpoint in Locally Advanced or Metastatic MSI/dMMR Esogastric Adenocarcinomas

Who this might be right for
Gastric CancerMSI-HMetastatic Cancer+1 more
Centre Leon Berard 132
Testing effectiveness (Phase 2)UnknownNCT04659382
What this trial is testing

Study to Evaluate Efficacy and Safety of Selective Internal Radiation Therapy Plus Xelox, Bevacizumab and Atezolizumab (Immune Chekpoint Inhibitor) in Patients With Liver-dominant Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal CancerpMMRMSS+2 more
Federation Francophone de Cancerologie Digestive 52
Testing effectiveness (Phase 2)Study completedNCT06478043
What this trial is testing

Investigate the Efficacy and Safety of Ivonescimab Combined With Irinotecan Liposome as Second-line Regimen for SCLC

Who this might be right for
Small-cell Lung Cancer
Zhejiang Cancer Hospital 60
Early research (Phase 1)Looking for participantsNCT06270706
What this trial is testing

PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid Tumor
Pliant Therapeutics, Inc. 124
Testing effectiveness (Phase 2)UnknownNCT03544723
What this trial is testing

Safety and Efficacy of p53 Gene Therapy Combined With Immune Checkpoint Inhibitors in Solid Tumors.

Who this might be right for
Solid TumorLymphoma
MultiVir, Inc. 40
Large-scale testing (Phase 3)Ended earlyNCT03729245
What this trial is testing

Bempegaldesleukin (NKTR-214: BEMPEG) in Combination With Nivolumab Compared With the Investigator's Choice of a Tyrosine Kinase Inhibitor (TKI) Therapy (Either Sunitinib or Cabozantinib Monotherapy) for Advanced Metastatic Renal Cell Carcinoma (RCC)

Who this might be right for
Renal Cell CarcinomaMetastatic Renal Cell Carcinoma
Nektar Therapeutics 623
Testing effectiveness (Phase 2)UnknownNCT05824494
What this trial is testing

Cadonilimab Plus Nab -Paclitaxel for Patients With Recurrent, or Metastatic Cervical Cancer Resistant to Immune Checkpoint Inhibitors

Who this might be right for
Uterine Cervical NeoplasmsCancer of CervixCervical Cancer+3 more
Women's Hospital School Of Medicine Zhejiang University 58
Testing effectiveness (Phase 2)Looking for participantsNCT06388031
What this trial is testing

ICI Rechallenge for Advanced NSCLC With Long-Term Response to First-Line ICI

Who this might be right for
Non-small Cell Lung Cancer
Peking Union Medical College Hospital 27
Not applicableStudy completedNCT07631611
What this trial is testing

Organ-Specific Differences in Immunotherapy Response Among Metastatic Cancer Patients

Who this might be right for
Solid TumorsMetastatic Cancer to LiverMetastatic Cancer to the Bone+5 more
Wenlong Zhong, MD 938
Testing effectiveness (Phase 2)Looking for participantsNCT07213830
What this trial is testing

Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies

Who this might be right for
Advanced Solid TumorMetastatic Solid Tumor
Ipsen 102
Large-scale testing (Phase 3)Looking for participantsNCT06581406
What this trial is testing

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

Who this might be right for
Metastatic Uveal Melanoma
Replimune, Inc. 280
Not applicableLooking for participantsNCT06864481
What this trial is testing

Prospective Cohort of Immune Checkpoint Inhibitor-induced Hepatitis

Who this might be right for
Liver InjurySecondary to Immune Checkpoint InhibitorsCancer Patients
University Hospital, Montpellier 250
Early research (Phase 1)Active Not RecruitingNCT06487559
What this trial is testing

Assess the Adverse Events and How Intravenously Infused Livmoniplimab in Combination With Budigalimab Moves Through the Bodies of Adult Chinese Participants With Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC)

Who this might be right for
Hepatocellular Carcinoma (HCC)
AbbVie 3
Testing effectiveness (Phase 2)Looking for participantsNCT07071103
What this trial is testing

Intestinal Low Dose Radiotherapy Combined With Immunotherapy in Immune-resistant Metastatic Malignant Solid Tumors

Who this might be right for
RadiotherapyMetastatic Solid CancersImmune Checkpoint Blockade+3 more
Chuangzhen Chen 48
Large-scale testing (Phase 3)Looking for participantsNCT06472245
What this trial is testing

Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor

Who this might be right for
Patients With Non-Small Cell Lung Cancer
OSE Immunotherapeutics 363
Early research (Phase 1)Active Not RecruitingNCT06377111
What this trial is testing

Test the Benefit of Vitamin B5 in Patients With Melanoma

Who this might be right for
Melanoma (Skin)
University Health Network, Toronto 12
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