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Results for “Secondary to Immune Checkpoint Inhibitors”

60 trials

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Showing 20 of 60 results

Testing effectiveness (Phase 2)Looking for participantsNCT07213830
What this trial is testing

Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies

Who this might be right for
Advanced Solid TumorMetastatic Solid Tumor
Ipsen 102
Early research (Phase 1)Ended earlyNCT05695898
What this trial is testing

XmAb23104 (PD1 X ICOS) and XmAb22841 (CTLA-4 X LAG3) in Treating Melanoma Prior Immune Checkpoint Inhibitor Therapy

Who this might be right for
Metastatic MelanomaAdvanced Melanoma
University of California, San Francisco 6
Testing effectiveness (Phase 2)UnknownNCT06172634
What this trial is testing

A Single-center Clinical Study to Evaluate the Safety and Efficacy of Autologous Bone Marrow-derived DCs(CellgramDC-WT1) and Immune Checkpoint Inhibitors in Patients With Metastatic Pancreatic Cancer Who Have Failed First-line or More Standard Chemotherapy

Who this might be right for
Pancreas Cancer
Soonchunhyang University Hospital 10
Early research (Phase 1)Looking for participantsNCT06487559
What this trial is testing

Assess the Adverse Events and How Intravenously Infused Livmoniplimab in Combination With Budigalimab Moves Through the Bodies of Adult Chinese Participants With Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC)

Who this might be right for
Hepatocellular Carcinoma (HCC)
AbbVie 20
Early research (Phase 1)Study completedNCT03666273
What this trial is testing

Phase 1 Study of BAY1905254 - An Early Clinical Research Study to Evaluate a New Drug Called Bapotulimab (BAY1905254) in the Expansion Cohort in Combination With Pembrolizumab in Head and Neck Cancer That Has Returned or is Discovered to be Metastatic and is Expressing PDL1.

Who this might be right for
Advanced Solid TumorHead and Neck Squamous Cell Carcinoma
Bayer 60
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07378761
What this trial is testing

Comparing UDCA and Corticosteroids in Immunotherapy Induced Cholestatic Hepatitis

Who this might be right for
Immune-Mediated Cholestasis
University Hospital, Montpellier 94
Not applicableLooking for participantsNCT07223411
What this trial is testing

Opdualag vs. Cemiplimab/Fianlimab in Relation to the Immunological Response in Tumor and Peripheral Blood in Unresectable or Metastatic Melanoma

Who this might be right for
Locally Advanced Melanoma
John Kirkwood 20
Not applicableStudy completedNCT07436390
What this trial is testing

IFN-Gamma Expression as a Predictor of Response to Immune Checkpoint Inhibitors in First-Line Metastatic Melanoma

Who this might be right for
Metastatic MelanomaMalignant MelanomaSkin Cancer
Institute of Oncology Ljubljana 132
Not applicableLooking for participantsNCT06784778
What this trial is testing

Observational Study of Patients With Advanced Melanoma (Skin Cancer) to Assess if IOpener®-Melanoma Test Can Predict Response to Immunotherapy.

Who this might be right for
Melanoma MetastaticMelanoma, SkinMelanoma Stage III or IV+1 more
Pamgene International B.V. 196
Large-scale testing (Phase 3)Ended earlyNCT04338269
What this trial is testing

Atezolizumab in Combination With Cabozantinib Compared to Cabozantinib Alone in Participants With Advanced Renal Cell Carcinoma After Immune Checkpoint Inhibitor Treatment

Who this might be right for
Carcinoma, Renal Cell
Hoffmann-La Roche 522
Early research (Phase 1)Study completedNCT05231746
What this trial is testing

HSTC810 With Advanced/Metastatic Solid Tumors (STCUBE-001)

Who this might be right for
Advanced Solid Tumor
STCube, Inc. 47
Early research (Phase 1)Active Not RecruitingNCT05334329
What this trial is testing

Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab for the Treatment of Non-small Cell Lung Cancer Previously Treated With PD-1 and/or PD-L1 Immune Checkpoint Inhibitors

Who this might be right for
Advanced Lung Non-Small Cell CarcinomaMetastatic Lung Non-Small Cell CarcinomaRecurrent Lung Non-Small Cell Carcinoma+8 more
University of California, Irvine 6
Testing effectiveness (Phase 2)Looking for participantsNCT06917092
What this trial is testing

QL1706-Based Therapy Post-PD-1/L1 Failure in Advanced Endometrial Cancer

Who this might be right for
Endometrial AdenocarcinomaEndometrial Cancer
Tianjin Medical University Cancer Institute and Hospital 30
Early research (Phase 1)Ended earlyNCT04628780
What this trial is testing

Study to Test the Safety and Tolerability of PF-07209960 in Advanced or Metastatic Solid Tumors

Who this might be right for
Non-small-cell Lung CancerSquamous Cell Carcinoma of the Head and NeckRenal Cell Carcinoma+3 more
Pfizer 37
Large-scale testing (Phase 3)Active Not RecruitingNCT04590963
What this trial is testing

Assessment of Efficacy and Safety of Monalizumab Plus Cetuximab Compared to Placebo Plus Cetuximab in Recurrent or Metastatic Head and Neck Cancer

Who this might be right for
Squamous Cell Carcinoma of the Head and Neck
AstraZeneca 370
Early research (Phase 1)Ended earlyNCT03996473
What this trial is testing

Study to Test the Safety and How Radium-223 Dichloride an Alpha Particle-emitting Radioactive Agent Works in Combination With Pembrolizumab an Immune Checkpoint Inhibitor in Patients With Stage IV Non-small Cell Lung Cancer With Bone Metastases

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Bayer 8
Early research (Phase 1)UnknownNCT06356701
What this trial is testing

Tumor Nutritional Therapy in the First-line Treatment of Stage IV NSCLC

Who this might be right for
Long-Term Effects Secondary to Cancer Therapy
The First Affiliated Hospital of Dalian Medical University 120
Large-scale testing (Phase 3)Looking for participantsNCT06581406
What this trial is testing

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

Who this might be right for
Metastatic Uveal Melanoma
Replimune, Inc. 280
Large-scale testing (Phase 3)Ended earlyNCT03729245
What this trial is testing

Bempegaldesleukin (NKTR-214: BEMPEG) in Combination With Nivolumab Compared With the Investigator's Choice of a Tyrosine Kinase Inhibitor (TKI) Therapy (Either Sunitinib or Cabozantinib Monotherapy) for Advanced Metastatic Renal Cell Carcinoma (RCC)

Who this might be right for
Renal Cell CarcinomaMetastatic Renal Cell Carcinoma
Nektar Therapeutics 623
Large-scale testing (Phase 3)Looking for participantsNCT05727904
What this trial is testing

Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.

Who this might be right for
Metastatic MelanomaUnresectable MelanomaMelanoma
Iovance Biotherapeutics, Inc. 670
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