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Results for “Secondary-Progressive Multiple Sclerosis”

166 trials

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Showing 20 of 166 results

Post-approval studies (Phase 4)Active Not RecruitingNCT05090371
What this trial is testing

Study of Continued Current Therapy vs Transition to Ofatumumab After Neurofilament (NfL) Elevation

Who this might be right for
Relapsing-Remitting Multiple Sclerosis
Novartis Pharmaceuticals 136
Large-scale testing (Phase 3)Study completedNCT00869726
What this trial is testing

Patients With Secondary Progressive Multiple Sclerosis

Who this might be right for
Secondary Progressive Multiple Sclerosis
Eli Lilly and Company 596
Not applicableUnknownNCT04993274
What this trial is testing

Sensitivity of Motor Assessment in MS - a Prospective Cohort Study

Who this might be right for
Multiple Sclerosis, Relapsing-RemittingMultiple Sclerosis, Secondary ProgressiveMultiple Sclerosis, Chronic Progressive
Friedemann Paul 100
Not applicableStudy completedNCT06526000
What this trial is testing

Study to Assess Changes in Immunoglobulins in Patients With Relapsing Multiple Sclerosis Treated With Anti-CD20 Therapies

Who this might be right for
Relapsing Multiple SclerosisClinically Isolated SyndromeRelapsing-remitting Multiple Sclerosis+1 more
Novartis 326
Post-approval studies (Phase 4)Study completedNCT04792567
What this trial is testing

Exploring the Immune Response to SARS-CoV-2 modRNA Vaccines in Patients With Secondary Progressive Multiple Sclerosis (AMA-VACC)

Who this might be right for
Secondary Progressive Multiple Sclerosis
Novartis Pharmaceuticals 41
Early research (Phase 1)Looking for participantsNCT06680037
What this trial is testing

Assess the Safety and Clinical Activity of Azer-cel in Participants With B-cell Mediated Autoimmune Disorders

Who this might be right for
B-cell Mediated Autoimmune Disorders
TG Therapeutics, Inc. 32
Large-scale testing (Phase 3)Active Not RecruitingNCT05441488
What this trial is testing

Masitinib in the Treatment of Patients With Primary Progressive or Non-active Secondary Progressive Multiple Sclerosis

Who this might be right for
Progressive Multiple Sclerosis
AB Science 800
Not applicableStudy completedNCT00888277
What this trial is testing

Bayer/Cognitive Assessments With Multiple Sclerosis Subjects

Who this might be right for
Multiple Sclerosis, Relapsing-remittingMultiple Sclerosis, Secondary Progressive
University of Louisville 74
Large-scale testing (Phase 3)Active Not RecruitingNCT05156281
What this trial is testing

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

Who this might be right for
Relapsing Multiple Sclerosis
Novartis Pharmaceuticals 1,011
Testing effectiveness (Phase 2)Study completedNCT00342134
What this trial is testing

Immunological Mechanisms of Hematopoietic Stem Cell Transplantation in Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
National Institute of Neurological Disorders and Stroke (NINDS) 34
Large-scale testing (Phase 3)Study completedNCT00134563
What this trial is testing

Study of Teriflunomide in Reducing the Frequency of Relapses and Accumulation of Disability in Patients With Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
Sanofi 1,088
Large-scale testing (Phase 3)Ended earlyNCT04925557
What this trial is testing

Study to Assess the Efficacy of Mayzent on Microglia in Secondary Progressive Multiple Sclerosis

Who this might be right for
Secondary-progressive Multiple Sclerosis
State University of New York at Buffalo 8
Not applicableAvailableNCT06802328
What this trial is testing

Intermediate-Size Patient Population Expanded Access: Foralumab in Non-Active Secondary Progressive MS Patients

Who this might be right for
Non-Active Secondary Progressive Multiple Sclerosis
Tiziana Life Sciences LTD
Testing effectiveness (Phase 2)UnknownNCT05013463
What this trial is testing

Hydroxychloroquine and Indapamide in SPMS

Who this might be right for
Multiple Sclerosis, Secondary Progressive
University of Calgary 35
Testing effectiveness (Phase 2)Study completedNCT01056471
What this trial is testing

Autologous Mesenchymal Stem Cells From Adipose Tissue in Patients With Secondary Progressive Multiple Sclerosis

Who this might be right for
Autoimmune DiseasesImmune System DiseasesDemyelinating Diseases+3 more
Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud 30
Early research (Phase 1)Study completedNCT00559702
What this trial is testing

Safety Study of Natalizumab to Treat Multiple Sclerosis (MS)

Who this might be right for
Relapsing-Remitting Multiple SclerosisSecondary Progressive Multiple Sclerosis
Biogen 76
Large-scale testing (Phase 3)Looking for participantsNCT06141486
What this trial is testing

Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
Sanofi 900
Early research (Phase 1)Not Yet RecruitingNCT06900192
What this trial is testing

Allogeneic Hematopoietic Cell Transplantation for Primary Progressive Multiple Sclerosis

Who this might be right for
Primary Progressive Multiple SclerosisMultiple SclerosisMultiple Sclerosis, Primary Progressive+1 more
Stanford University 10
Large-scale testing (Phase 3)Study completedNCT00241254
What this trial is testing

Efficacy of Cyclophosphamide Versus Methylprednisolone in Patients With Secondary Progressive Multiple Sclerosis

Who this might be right for
Multiple Sclerosis, Chronic Progressive
University Hospital, Bordeaux 138
Not applicableStudy completedNCT06588387
What this trial is testing

A Real-world Study to Assess the Use of Siponimod in Spain to Treat Patients With Secondary Progressive Multiple Sclerosis

Who this might be right for
Secondary Progressive Multiple Sclerosis
Novartis 210
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