Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Secondary-Progressive Multiple Sclerosis”

168 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 168 results

Large-scale testing (Phase 3)Ended earlyNCT01416181
What this trial is testing

A Clinical Study of the Efficacy of Natalizumab on Reducing Disability Progression in Participants With Secondary Progressive Multiple Sclerosis

Who this might be right for
Secondary Progressive Multiple Sclerosis
Biogen 889
Very early researchStudy completedNCT05357833
What this trial is testing

Novel Imaging Markers in SPMS

Who this might be right for
Secondary Progressive Multiple SclerosisMultiple Sclerosis, Secondary ProgressiveMultiple Sclerosis
University of Utah 11
Testing effectiveness (Phase 2)Study completedNCT00228163
What this trial is testing

Long Term Safety and Efficacy of Teriflunomide (HMR1726) in Multiple Sclerosis With Relapses

Who this might be right for
Multiple Sclerosis
Sanofi 147
Not applicableStudy completedNCT02207075
What this trial is testing

Measuring Active Microglia in Progressive Multiple Sclerosis

Who this might be right for
Secondary Progressive Multiple Sclerosis
Weill Medical College of Cornell University 50
Not applicableStudy completedNCT03094364
What this trial is testing

Video Game-based Therapy for Arm Weakness In Progressive Multiple Sclerosis

Who this might be right for
Primary Progressive Multiple SclerosisHemiparesis
University of Massachusetts, Lowell 31
Early research (Phase 1)WithdrawnNCT05029609
What this trial is testing

Phase 1b Multiple Ascending Dose Study of Foralumab in Primary and Secondary Progressive MS

Who this might be right for
Primary Progressive Multiple SclerosisSecondary Progressive Multiple SclerosisMultiple Sclerosis
Tiziana Life Sciences LTD
Testing effectiveness (Phase 2)UnknownNCT01466114
What this trial is testing

Estriol Treatment in Multiple Sclerosis (MS): Effect on Cognition

Who this might be right for
Relapsing-remitting Multiple SclerosisSecondary-progressive Multiple SclerosisPrimary-progressive Multiple Sclerosis
University of California, Los Angeles 64
Large-scale testing (Phase 3)Study completedNCT00134563
What this trial is testing

Study of Teriflunomide in Reducing the Frequency of Relapses and Accumulation of Disability in Patients With Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
Sanofi 1,088
Testing effectiveness (Phase 2)Study completedNCT00342134
What this trial is testing

Immunological Mechanisms of Hematopoietic Stem Cell Transplantation in Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
National Institute of Neurological Disorders and Stroke (NINDS) 34
Large-scale testing (Phase 3)Study completedNCT01665144
What this trial is testing

Exploring the Efficacy and Safety of Siponimod in Patients With Secondary Progressive Multiple Sclerosis (EXPAND)

Who this might be right for
Secondary Progressive Multiple Sclerosis
Novartis Pharmaceuticals 1,651
Large-scale testing (Phase 3)Study completedNCT00799890
What this trial is testing

Sunphenon in Progressive Forms of Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
Friedemann Paul 61
Early research (Phase 1)Study completedNCT06683612
What this trial is testing

PET Study of PIPE-791 in Healthy Volunteers and Volunteers With PrMS and IPF

Who this might be right for
Idiopathic Pulmonary Fibrosis (IPF)Idiopathic Pulmonary FibrosisMultiple Sclerosis+6 more
Contineum Therapeutics 16
Large-scale testing (Phase 3)Active Not RecruitingNCT05156281
What this trial is testing

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

Who this might be right for
Relapsing Multiple Sclerosis
Novartis Pharmaceuticals 1,011
Not applicableEnded earlyNCT04746976
What this trial is testing

Study of Diroximel Fumarate in the Real-World Setting

Who this might be right for
Relapsing Forms of MS
Biogen 75
Not applicableLooking for participantsNCT07426991
What this trial is testing

Cognitive Performance, Sleep Disturbances and Fatigue in Multiple Sclerosis

Who this might be right for
Multiple SclerosisRemitting-Relapsing Multiple SclerosisPrimary Progressive Multiple Sclerosis+3 more
Heinrich-Heine University, Duesseldorf 837
Very early researchStudy completedNCT05349474
What this trial is testing

Metformin Treatment in Progressive Multiple Sclerosis

Who this might be right for
Secondary Progressive Multiple SclerosisPrimary Progressive Multiple Sclerosis
University of California, Los Angeles 23
Early research (Phase 1)Ended earlyNCT01318421
What this trial is testing

ELND002 in Patients With Relapsing Forms of Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
Elan Pharmaceuticals 12
Not applicableActive Not RecruitingNCT03983681
What this trial is testing

Evaluation of a Theory-Driven Manualized Approach to Improving New Learning and Memory in MS

Who this might be right for
Multiple Sclerosis
Kessler Foundation 120
Not applicableStudy completedNCT00888277
What this trial is testing

Bayer/Cognitive Assessments With Multiple Sclerosis Subjects

Who this might be right for
Multiple Sclerosis, Relapsing-remittingMultiple Sclerosis, Secondary Progressive
University of Louisville 74
Not applicableStudy completedNCT04940065
What this trial is testing

Special Drug-use Surveillance for Kesimpta for s.c. Injection 20 mg Pen

Who this might be right for
Relapsing-remitting Multiple SclerosisActive Secondary Progressive Multiple Sclerosis
Novartis Pharmaceuticals 367
Load More Results