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Results for “Select Advanced Malignancies”

511 trials

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Showing 20 of 511 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04969887
What this trial is testing

Combination Immunotherapy in Rare Cancers Under InvesTigation

Who this might be right for
Advanced Biliary Tract CancerNeuroendocrine TumorsFemale Reproductive System Neoplasm+1 more
Olivia Newton-John Cancer Research Institute 240
Large-scale testing (Phase 3)Not Yet RecruitingNCT07601048
What this trial is testing

A Trial of HRS-7058 in Advanced or Metastatic Non-Small Cell Lung Cancer Patients Who Have Failed Standard Treatment

Who this might be right for
KRAS G12C-positive Advanced or Metastatic Non-Small Cell Lung Cancer Patients Who Have Failed Standard Treatment
Shandong Suncadia Medicine Co., Ltd. 450
Early research (Phase 1)Study completedNCT02723955
What this trial is testing

Dose Escalation and Expansion Study of GSK3359609 in Participants With Selected Advanced Solid Tumors (INDUCE-1)

Who this might be right for
Neoplasms
GlaxoSmithKline 829
Testing effectiveness (Phase 2)Active Not RecruitingNCT02671435
What this trial is testing

Durvalumab (MEDI4736) and Monalizumab in Solid Tumors

Who this might be right for
Advanced Solid Tumors
MedImmune LLC 383
Large-scale testing (Phase 3)Looking for participantsNCT05549297
What this trial is testing

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

Who this might be right for
Advanced Melanoma
Immunocore Ltd 540
Testing effectiveness (Phase 2)Ended earlyNCT04059484
What this trial is testing

Phase 2 Study of Amcenestrant (SAR439859) Versus Physician's Choice in Locally Advanced or Metastatic ER-positive Breast Cancer

Who this might be right for
Breast Cancer Metastatic
Sanofi 367
Early research (Phase 1)Study completedNCT02221960
What this trial is testing

Evaluate MEDI6383 Alone and in Combination With MEDI4736 in Adult Subjects With Select Advanced Solid Tumors

Who this might be right for
Recurrent or Metastatic Solid Tumors
MedImmune LLC 39
Large-scale testing (Phase 3)Looking for participantsNCT05760378
What this trial is testing

Famitinib in Combination With Camrelizumab and TPC in The First-line Treatment of Immunomodulatory Locally Advanced or Metastatic TNBC.

Who this might be right for
Triple-Negative Breast Cancer
Fudan University 223
Early research (Phase 1)Not Yet RecruitingNCT07797907
What this trial is testing

This Clinical Study is to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Preliminary Antitumor Activity of BD200 in Participants With Advanced or Metastatic Cancer.

Who this might be right for
Solid Tumor (Phase I)
Biolojic Design Ltd. 110
Large-scale testing (Phase 3)Active Not RecruitingNCT04975308
What this trial is testing

Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer

Who this might be right for
Breast NeoplasmsNeoplasm Metastasis
Eli Lilly and Company 874
Early research (Phase 1)Study completedNCT01928459
What this trial is testing

Phase 1b Trial of BGJ398/BYL719 in Solid Tumors

Who this might be right for
Advanced Solid TumorsMetastatic Solid Tumors
Novartis Pharmaceuticals 62
Early research (Phase 1)Study completedNCT02526017
What this trial is testing

Study of Cabiralizumab in Combination With Nivolumab in Patients With Selected Advanced Cancers

Who this might be right for
Advanced Solid TumorsHead and Neck CancerPancreatic Cancer+4 more
Five Prime Therapeutics, Inc. 313
Testing effectiveness (Phase 2)Looking for participantsNCT05867420
What this trial is testing

ASKG915 in Patients With Selected Advanced Solid Tumors.

Who this might be right for
Advanced Solid Tumors
AskGene Pharma, Inc. 594
Large-scale testing (Phase 3)Looking for participantsNCT07185997
What this trial is testing

Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations

Who this might be right for
Non-Small-Cell Lung CancerMetastatic Non-Small-Cell Lung CancerAdvanced Non-Small-Cell Lung Cancer+3 more
ArriVent BioPharma, Inc.
Testing effectiveness (Phase 2)Active Not RecruitingNCT06237881
What this trial is testing

KSQ-001EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate the SOCS1 Gene, in Patients With Select Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorMelanomaLung Neoplasms+1 more
M.D. Anderson Cancer Center 15
Testing effectiveness (Phase 2)Study completedNCT02318277
What this trial is testing

Epacadostat (INCB024360) in Combination With Durvalumab (MEDI4736) in Subjects With Selected Advanced Solid Tumors (ECHO-203)

Who this might be right for
Solid TumorsHead and Neck CancerLung Cancer+1 more
Incyte Corporation 176
Large-scale testing (Phase 3)Ended earlyNCT04746924
What this trial is testing

Ociperlimab With Tislelizumab Compared to Pembrolizumab in Participants With Untreated Lung Cancer

Who this might be right for
Non-small Cell Lung CancerNSCLC
BeiGene 669
Not applicableStudy completedNCT04789980
What this trial is testing

Good Choice of pALliative Chemotherapy to Patient With Pancreatic Cancer ; GemcitAbine Therapy vs FOLFORINOX therapY

Who this might be right for
Locally Advanced Pancreatic CancerMetastatic Pancreatic Cancer
Boryung Pharmaceutical Co., Ltd 799
Testing effectiveness (Phase 2)Ended earlyNCT05109442
What this trial is testing

Study to Assess AFM24 in Combination With Atezolizumab in Selected Advanced/Metastatic EGFR-expressing Cancers

Who this might be right for
Advanced Solid Tumor
Affimed GmbH 112
Not applicableWithdrawnNCT03419247
What this trial is testing

Molecular Profiling of Advanced Biliary Tract Cancers

Who this might be right for
Biliary Tract Cancer
University Health Network, Toronto
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