Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Select Advanced Malignancies”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT03210714
What this trial is testing

Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent Childhood EpendymomaRecurrent Childhood Malignant Germ Cell Tumor+29 more
National Cancer Institute (NCI) 20
Testing effectiveness (Phase 2)WithdrawnNCT05234606
What this trial is testing

A Safety and Preliminary Efficacy Study of SBT6290 Alone and in Combination With PD-(L)1 Inhibitors in Select Advanced Solid Tumors

Who this might be right for
Urothelial CarcinomaTriple Negative Breast CancerNon-small Cell Lung Cancer+2 more
Silverback Therapeutics
Testing effectiveness (Phase 2)Study completedNCT02983045
What this trial is testing

A Dose Escalation and Cohort Expansion Study of NKTR-214 in Combination With Nivolumab and Other Anti-Cancer Therapies in Patients With Select Advanced Solid Tumors

Who this might be right for
MelanomaRenal Cell CarcinomaNon Small Cell Lung Cancer+4 more
Nektar Therapeutics 557
Large-scale testing (Phase 3)Not Yet RecruitingNCT07621601
What this trial is testing

HS-20093 in Patients With Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC)

Who this might be right for
Esophageal Squamous Cell Carcinoma (ESCC)
Hansoh BioMedical R&D Company 494
Early research (Phase 1)Study completedNCT05538572
What this trial is testing

PRT3645 in Participants With Select Advanced or Metastatic Solid Tumors

Who this might be right for
Breast CancerGlioblastomaHead and Neck Squamous Cell Carcinoma+4 more
Prelude Therapeutics Incorporated 22
Testing effectiveness (Phase 2)Looking for participantsNCT05564377
What this trial is testing

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Who this might be right for
Advanced Malignant Solid NeoplasmAnatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8+12 more
National Cancer Institute (NCI) 2,900
Early research (Phase 1)Ended earlyNCT05494762
What this trial is testing

Safety, Pharmacokinetics, and Antitumor Activity of BGB-B167 Alone and in Combination With Tislelizumab (BGB-A317) in Participants With Advanced Solid Tumors

Who this might be right for
Solid Tumor
BeiGene 55
Early research (Phase 1)Active Not RecruitingNCT03530397
What this trial is testing

Evaluate MEDI5752 in Subjects With Advanced Solid Tumors

Who this might be right for
Selected Advanced Solid Tumors
MedImmune LLC 400
Early research (Phase 1)Study completedNCT02318394
What this trial is testing

MEDI0562 in Adult Subjects With Selected Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
MedImmune LLC 56
Early research (Phase 1)Looking for participantsNCT06084481
What this trial is testing

Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400

Who this might be right for
Hepatocellular CarcinomaPancreatic Ductal AdenocarcinomaBiliary Tract Cancers+5 more
AbbVie 325
Testing effectiveness (Phase 2)Study completedNCT00085501
What this trial is testing

S0342: Paclitaxel, Carboplatin, and Cetuximab in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

Who this might be right for
Lung Cancer
SWOG Cancer Research Network 242
Not applicableLooking for participantsNCT07109154
What this trial is testing

DeniLA: Comprehensive Demographics and Clinical Profile of NSCLC Patients: Analyzing Guideline-Concordant Care in First-line Treatment Patterns

Who this might be right for
Lung Neoplasms
AstraZeneca 200
Large-scale testing (Phase 3)Looking for participantsNCT06380751
What this trial is testing

Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

Who this might be right for
Advanced Breast Cancer
AstraZeneca 788
Testing effectiveness (Phase 2)Ended earlyNCT01708161
What this trial is testing

A Phase Ib/II Study of the Combination of BYL719 Plus AMG 479 in Adult Patients With Selected Solid Tumors

Who this might be right for
PIK3CA Mutated Advanced Solid TumorsPIK3CA Amplified Advanced Solid Tumors
Novartis Pharmaceuticals 47
Testing effectiveness (Phase 2)Study completedNCT03495882
What this trial is testing

Zalifrelimab and Balstilimab for Treatment of Participants With Metastatic or Locally Advanced Solid Tumors, and Expansion Into Select Solid Tumors (Cervical)

Who this might be right for
Cervical Cancer
Agenus Inc. 175
Early research (Phase 1)Study completedNCT03597581
What this trial is testing

RGX-202-01 (Ompenaclid) as Combination Therapy in RAS Mutant Advanced Colorectal Cancer

Who this might be right for
Gastrointestinal CancerGastrointestinal NeoplasmsColorectal Cancer+7 more
Inspirna, Inc. 89
Early research (Phase 1)Ended earlyNCT03621982
What this trial is testing

Study of ADCT-301 in Patients With Selected Advanced Solid Tumors

Who this might be right for
Head and Neck Cancer Squamous Cell CarcinomaNon-small Cell Lung CancerGastric Cancer+9 more
ADC Therapeutics S.A. 78
Testing effectiveness (Phase 2)Active Not RecruitingNCT04320888
What this trial is testing

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

Who this might be right for
Hematopoietic and Lymphatic System NeoplasmRecurrent EpendymomaRecurrent Ewing Sarcoma+35 more
National Cancer Institute (NCI) 1
Testing effectiveness (Phase 2)Looking for participantsNCT05394103
What this trial is testing

Highly Selective CDK7 Inhibitor Q901 in Selected Advanced Solid Tumors

Who this might be right for
Advanced CancerMetastatic Cancer
Qurient Co., Ltd. 130
Not applicableStudy completedNCT02750657
What this trial is testing

Study of Changes and Characteristics of Genes in Patients With Pancreatic Cancer for Better Treatment Selection

Who this might be right for
Carcinoma, Pancreatic Ductal
University Health Network, Toronto 332
Next Page