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Results for “Select Advanced Malignancies”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Ended earlyNCT01562899
What this trial is testing

MEK162 and AMG 479 in Patients With Selected Solid Tumors

Who this might be right for
Metastatic Pancreatic AdenocarcinomaBRAF Mutated Melanoma
Pfizer 77
Testing effectiveness (Phase 2)Active Not RecruitingNCT06399757
What this trial is testing

Investigate APL-5125 in Adults With Advanced Solid Tumors

Who this might be right for
Colorectal CancerCholangiocarcinomaAppendiceal Adenocarcinoma+6 more
Apollo Therapeutics Ltd 100
Large-scale testing (Phase 3)Active Not RecruitingNCT04211337
What this trial is testing

Selpercatinib (LY3527723) in Participants With RET-Mutant Medullary Thyroid Cancer

Who this might be right for
Medullary Thyroid Cancer
Loxo Oncology, Inc. 291
Testing effectiveness (Phase 2)Ended earlyNCT03149549
What this trial is testing

PROCLAIM-CX-2009: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2009 for Patients With Selected Solid Tumors

Who this might be right for
Solid Tumor, AdultBreast CancerNon Small Cell Lung Cancer+2 more
CytomX Therapeutics 99
Testing effectiveness (Phase 2)Study completedNCT05661578
What this trial is testing

Evaluate the Safety and Pharmacokinetics of the Intravenous Fixed-Dose Combination (IV FDC) of Tiragolumab and Atezolizumab in Participants With Locally Advanced, Recurrent or Metastatic Solid Tumors

Who this might be right for
PD-L1-selected Solid Tumors
Hoffmann-La Roche 64
Testing effectiveness (Phase 2)Active Not RecruitingNCT05565378
What this trial is testing

A Platform Study of Novel Immunotherapy Combinations in Participants With Previously Untreated, Advanced/Metastatic Non-Small-Cell Lung Cancer

Who this might be right for
Lung Cancer, Non-Small Cell
GlaxoSmithKline 351
Large-scale testing (Phase 3)Looking for participantsNCT07463573
What this trial is testing

QLC5508 vs. Chemotherapy in Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma (ESCC)
Qilu Pharmaceutical Co., Ltd. 466
Testing effectiveness (Phase 2)Ended earlyNCT03681951
What this trial is testing

First-time-in-human (FTIH) Study of GSK3145095 Alone and in Combination With Other Anticancer Agents in Adults With Advanced Solid Tumors

Who this might be right for
Neoplasms, Pancreatic
GlaxoSmithKline 8
Testing effectiveness (Phase 2)Study completedNCT00661193
What this trial is testing

S0709: Erlotinib With or Without Carboplatin and Paclitaxel in Stage IIIB or Stage IV Non-Small Cell Lung Cancer

Who this might be right for
Lung Cancer
SWOG Cancer Research Network 59
Not applicableStudy completedNCT02724488
What this trial is testing

Selection Pressure and Evolution Induced by Immune Checkpoint Inhibitors and Other Immunologic Therapies

Who this might be right for
Head and Neck CancerMelanoma
University Health Network, Toronto 14
Early research (Phase 1)Looking for participantsNCT05107674
What this trial is testing

NX-1607 in Adults With Advanced Malignancies

Who this might be right for
Ovarian Cancer, EpithelialGastric CancerGastroEsophageal Junction (GEJ) Cancer+11 more
Nurix Therapeutics, Inc. 345
Very early researchLooking for participantsNCT05141474
What this trial is testing

Assessment of the Safety and Tolerability of ex Vivo Next-generation Neoantigen-selected Tumor-infiltrating Lymphocyte (TIL) Therapy in Advanced Epithelial Tumors and Immune Checkpoint Blockade (ICB) Resistant Solid Tumors

Who this might be right for
Epithelial Tumors, MalignantMalignant Solid Tumor
Vall d'Hebron Institute of Oncology 10
Early research (Phase 1)Study completedNCT03538028
What this trial is testing

A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignancies

Who this might be right for
Cervical CancerMicrosatellite Instability (MSI)-High Endometrial CancerGastric Cancer (Including Stomach and Gastroesophageal Junction [GEJ])+14 more
Incyte Biosciences International Sàrl 22
Large-scale testing (Phase 3)Active Not RecruitingNCT05170204
What this trial is testing

A Study Evaluating the Efficacy and Safety of Multiple Therapies in Cohorts of Participants With Locally Advanced, Unresectable, Stage III Non-Small Cell Lung Cancer (NSCLC)

Who this might be right for
Non-Small Cell Lung Cancer
Hoffmann-La Roche 68
Testing effectiveness (Phase 2)Active Not RecruitingNCT02546232
What this trial is testing

Improved Breast Cancer Therapy (I-BCT-1) in the Neoadjuvant and Metastatic Setting

Who this might be right for
Breast Cancer
Oslo University Hospital 196
Testing effectiveness (Phase 2)Study completedNCT04172506
What this trial is testing

Evaluate the Efficacy and Safety of Anti-PD-1 Antibody AK105 in Patients With Selected Advanced Solid Tumors

Who this might be right for
Solid TumorLung CancerHCC
Akeso 65
Large-scale testing (Phase 3)Looking for participantsNCT06194734
What this trial is testing

KC1036 Versus Investigator's Choice of Chemotherapy in Patients With Advanced Esophageal Cancer

Who this might be right for
Esophageal Squamous Cell Carcinoma
Beijing Konruns Pharmaceutical Co., Ltd. 490
Large-scale testing (Phase 3)Looking for participantsNCT07062965
What this trial is testing

Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.

Who this might be right for
Breast Cancer
Pfizer 400
Large-scale testing (Phase 3)Looking for participantsNCT07071337
What this trial is testing

SKB264 Versus Investigator's Choice of Chemotherapy in Subjects With Unresectable Locally Advanced, Relapsed, or Metastatic HR+/HER2- Breast Cancer Who Have Previously Failed Endocrine Therapy

Who this might be right for
Metastatic Breast Cancer
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. 430
Early research (Phase 1)Looking for participantsNCT06400472
What this trial is testing

Sofe-M in Participants With Selected Advanced Solid Tumors

Who this might be right for
Ovarian NeoplasmsEndometrial NeoplasmsUterine Cervical Neoplasms+4 more
Eli Lilly and Company 575
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