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Results for “Select Advanced Solid Tumors”

270 trials

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Showing 20 of 270 results

Early research (Phase 1)Ended earlyNCT05573035
What this trial is testing

Investigate LYL845 in Adults With Solid Tumors

Who this might be right for
MelanomaNon-small Cell Lung CancerColorectal Cancer
Lyell Immunopharma, Inc. 39
Testing effectiveness (Phase 2)Looking for participantsNCT07462650
What this trial is testing

Dual-Target CAR-NK Cells for Biomarker-Selected Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticAdenocarcinoma of Colon
Beijing Biotech 48
Early research (Phase 1)Study completedNCT04087018
What this trial is testing

Study to Evaluate Safety and Clinical Activity of AB122 in Biomarker Selected Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Arcus Biosciences, Inc. 18
Early research (Phase 1)Ended earlyNCT05061537
What this trial is testing

Study of PF-07263689 in Participants With Selected Advanced Solid Tumors

Who this might be right for
Renal Cell CancerMelanomaNon-Small-Cell Lung Cancer+7 more
Pfizer 13
Testing effectiveness (Phase 2)Active Not RecruitingNCT04320888
What this trial is testing

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

Who this might be right for
Hematopoietic and Lymphatic System NeoplasmRecurrent EpendymomaRecurrent Ewing Sarcoma+35 more
National Cancer Institute (NCI) 1
Early research (Phase 1)Ended earlyNCT05576077
What this trial is testing

TBio-4101 (TIL) and Pembrolizumab in Patients With Advanced Solid Tumors

Who this might be right for
Breast CancerColorectal CancerUveal Melanoma+3 more
Turnstone Biologics, Corp. 31
Early research (Phase 1)Study completedNCT05585034
What this trial is testing

Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors

Who this might be right for
Head and Neck Squamous Cell CarcinomaMelanoma Excluding Uveal MelanomaNon-small Cell Lung Cancer, Squamous or Non-squamous+6 more
Xencor, Inc. 60
Early research (Phase 1)WithdrawnNCT05010096
What this trial is testing

BAY1895344 and Copanlisib for the Treatment of Molecularly Selected Patients With Advanced Solid Tumors

Who this might be right for
Locally Advanced Malignant Solid NeoplasmMetastatic Malignant Neoplasm in the BoneMetastatic Malignant Solid Neoplasm+1 more
M.D. Anderson Cancer Center
Early research (Phase 1)Study completedNCT02259114
What this trial is testing

A Dose-Finding Study of Birabresib (MK-8628), a Small Molecule Inhibitor of the Bromodomain and Extra-Terminal (BET) Proteins, in Adults With Selected Advanced Solid Tumors (MK-8628-003)

Who this might be right for
NUT Midline CarcinomaTriple Negative Breast CancerNon-small Cell Lung Cancer With Rearranged ALK Gene/Fusion Protein or KRAS Mutation+3 more
Oncoethix GmbH, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 47
Early research (Phase 1)Looking for participantsNCT06400472
What this trial is testing

Sofe-M in Participants With Selected Advanced Solid Tumors

Who this might be right for
Ovarian NeoplasmsEndometrial NeoplasmsUterine Cervical Neoplasms+4 more
Eli Lilly and Company 575
Testing effectiveness (Phase 2)Looking for participantsNCT06598371
What this trial is testing

KSQ-004EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate Genes Encoding SOCS1 and Regnase-1, in Patients With Select Advanced Solid Tumors

Who this might be right for
Select Advanced Solid Tumors
M.D. Anderson Cancer Center 141
Early research (Phase 1)Looking for participantsNCT06487624
What this trial is testing

An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors

Who this might be right for
Advanced Solid TumorRefractory Hodgkin Lymphoma
FBD Biologics Limited 50
Testing effectiveness (Phase 2)Study completedNCT03526250
What this trial is testing

Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent Childhood EpendymomaRecurrent Ewing Sarcoma+29 more
National Cancer Institute (NCI) 23
Testing effectiveness (Phase 2)Active Not RecruitingNCT03210714
What this trial is testing

Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent Childhood EpendymomaRecurrent Childhood Malignant Germ Cell Tumor+29 more
National Cancer Institute (NCI) 20
Testing effectiveness (Phase 2)Ended earlyNCT03149549
What this trial is testing

PROCLAIM-CX-2009: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2009 for Patients With Selected Solid Tumors

Who this might be right for
Solid Tumor, AdultBreast CancerNon Small Cell Lung Cancer+2 more
CytomX Therapeutics 99
Testing effectiveness (Phase 2)WithdrawnNCT05234606
What this trial is testing

A Safety and Preliminary Efficacy Study of SBT6290 Alone and in Combination With PD-(L)1 Inhibitors in Select Advanced Solid Tumors

Who this might be right for
Urothelial CarcinomaTriple Negative Breast CancerNon-small Cell Lung Cancer+2 more
Silverback Therapeutics
Testing effectiveness (Phase 2)Study completedNCT03495882
What this trial is testing

Zalifrelimab and Balstilimab for Treatment of Participants With Metastatic or Locally Advanced Solid Tumors, and Expansion Into Select Solid Tumors (Cervical)

Who this might be right for
Cervical Cancer
Agenus Inc. 175
Testing effectiveness (Phase 2)Looking for participantsNCT07158918
What this trial is testing

ABL103 in Combination With Pembrolizumab, With or Without Taxane in Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Tumors
ABL Bio, Inc. 65
Early research (Phase 1)Study completedNCT02526017
What this trial is testing

Study of Cabiralizumab in Combination With Nivolumab in Patients With Selected Advanced Cancers

Who this might be right for
Advanced Solid TumorsHead and Neck CancerPancreatic Cancer+4 more
Five Prime Therapeutics, Inc. 313
Early research (Phase 1)Study completedNCT01760525
What this trial is testing

A Phase I Dose Escalation Study of CGM097 in Adult Patients With Selected Advanced Solid Tumors

Who this might be right for
Solid Tumor With p53 Wild Type Status
Novartis Pharmaceuticals 51
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