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Results for “Serplulimab”

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Not applicableActive Not RecruitingNCT06748495
What this trial is testing

Real-world First-line Serplulimab-based Immunochemotherapy for Extensive-stage Small Cell Lung Cancer

Who this might be right for
Extensive-stage Small Cell Lung Cancer (ES-SCLC)
Hunan Cancer Hospital 600
Testing effectiveness (Phase 2)UnknownNCT05769725
What this trial is testing

Evaluate Serplulimab in Combination With Docetaxel +S-1 VS. Docetaxel +S-1 as Adjuvant Treatment Therapy in Stage IIIc Gastric Cancer

Who this might be right for
Serplulimab,Gastric Cancer, Adjuvant Therapy
RenJi Hospital 70
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07134101
What this trial is testing

Neoadjuvant Therapy for Locally Advanced Low Rectal Cancer (SMARTi-RC01)

Who this might be right for
Colorectal Cancer (Diagnosis)
The First Affiliated Hospital with Nanjing Medical University 138
Testing effectiveness (Phase 2)Looking for participantsNCT07347951
What this trial is testing

A Single-center, Phase II Study on Efficacy & Safety of SCRT+CAPOX+Serplulimab+Bevacizumab for MSS Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
First Affiliated Hospital of Wenzhou Medical University 30
Testing effectiveness (Phase 2)UnknownNCT06393166
What this trial is testing

Sequential AG and mFOLFOX Combined With Serplulimab Injection and Bevacizumab Injection in Untreated Advanced Pancreatic Cancer

Who this might be right for
Non-Resectable Pancreas Carcinoma
Zhejiang Cancer Hospital 37
Early research (Phase 1)Not Yet RecruitingNCT06882915
What this trial is testing

Efficacy and Safety of Trifluridine/Tipiracil (TAS-102) Combined With Bevacizumab and Serplulimab in Patients With Metastatic Colorectal Cancer Undergoing Cytoreductive Surgery: A Single-Arm, Single-Center Clinical Study

Who this might be right for
Colorectal Cancer (CRC)
Second Affiliated Hospital, Zhejiang University, School of Medicine 20
Testing effectiveness (Phase 2)UnknownNCT05942573
What this trial is testing

Continuation of Serplulimab Plus Chemotherapy After First Progression in Advanced Gastric or Gastro-oesophageal Junction Adenocarcinoma: an Open-label, Randomised Phase II Trial

Who this might be right for
Gastric Cancer (GC) Gastroesophageal Junction Cancer (GEJ)
Tianjin Medical University Cancer Institute and Hospital 107
Testing effectiveness (Phase 2)Active Not RecruitingNCT07538180
What this trial is testing

Serplulimab, Chidamide, and Rituximab Followed by Sequential R-CHOP for Newly Diagnosed Elderly MYC/BCL2 Double-Expressor DLBCL

Who this might be right for
Newly Diagnosed MYC/BCL2 Double-expressor DLBCL
Sun Yat-sen University 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07733050
What this trial is testing

Efficacy and Safety of Serplulimab in Combination With Bevacizumab and FOLFIRINOX or NALIRIFOX as Second-Line Therapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

Who this might be right for
Metastatic Pancreatic Ductal Adenocarcinoma
Shanghai General Hospital, China 34
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06554535
What this trial is testing

Efficacy and Safety of Serplulimab With Chemotherapy and Aspirin in Untreated Extensive-Stage Small Cell Lung Cancer

Who this might be right for
Extensive-Stage Small Cell Lung CancerTreatment-naïve for Systemic Therapy Targeting Extensive-Stage Small Cell Lung CancerECOG Performance Status Score of 0 or 1+1 more
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Testing effectiveness (Phase 2)UnknownNCT06491355
What this trial is testing

First-Line Treatment Induced With mFOLFOX6 and HLX04 Regimen, Following Combined With Serplulimab in MSS Initially Unresectable Metastatic Colorectal Cancer

Who this might be right for
Efficacy, SelfSafety IssuesColo-rectal Cancer
Sir Run Run Shaw Hospital 72
Testing effectiveness (Phase 2)Looking for participantsNCT06848699
What this trial is testing

A Phase Ib/II Clinical Study to Evaluate HLX43 in Combination With Serplulimab in Patients With Advanced/Metastatic Solid Tumors

Who this might be right for
Solid Tumor CancerNon Small Cell Lung Cancer
Shanghai Henlius Biotech 105
Early research (Phase 1)Active Not RecruitingNCT06394414
What this trial is testing

Evaluate the Safety, Efficacy, and Pharmacokinetics of YL201 in Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
MediLink Therapeutics (Suzhou) Co., Ltd. 187
Testing effectiveness (Phase 2)Active Not RecruitingNCT06394661
What this trial is testing

Serplulimab Plus Chemotherapy for Early-stage HR+/HER2- Breast Cancer

Who this might be right for
Breast Cancer
Henan Cancer Hospital 109
Testing effectiveness (Phase 2)Study completedNCT05775796
What this trial is testing

Evaluate the Efficacy and Safety of Serplulimab Plus Chemotherapy in Neoadjuvant and Adjuvant Treatment of Resectable NSCLC (ECTOP-1013)

Who this might be right for
Non-small Cell Lung CancerStage II-IIIAImmunotherapy+1 more
Fudan University 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07543848
What this trial is testing

A Prospective, Multicenter, Single-Arm Phase II Exploratory Study of Serplulimab Combined With Oncolytic Virus H101, Short-Course Radiotherapy, and XELOX Chemotherapy as Total Neoadjuvant Treatment for Locally Advanced (cT1-3N0M0) Rectal Cancer

Who this might be right for
Rectal NeoplasmsRectal Adenocarcinoma
Chongqing University Cancer Hospital 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT05513573
What this trial is testing

Phase II Clinical Study to Compare the Efficacy and Safety of HLX07 + Serplulimab +Chemotherapy Versus Placebo + Serplulimab + Chemotherapy in First-Line Treatment of Patients With Recurrent or Metastatic NPC

Who this might be right for
Nasopharyngeal Carcinoma by AJCC V8 Stage
Shanghai Henlius Biotech 75
Testing effectiveness (Phase 2)UnknownNCT06422858
What this trial is testing

Sequential Tegafur-gimeracil-oteracil Potassium Capsule (s-1) and Serplulimab Following Concurrent Chemoradiotherapy for Esophageal Squamous Cell Carcinoma

Who this might be right for
Locally Advanced Inoperable Esophageal Squamous Cell Carcinoma
Zhejiang Cancer Hospital 37
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07779694
What this trial is testing

16-Hour Fasting Plus Serplulimab and CAPEOX as Neoadjuvant Therapy in pMMR/MSS Advanced Mid-to-Low Rectal Cancer

Who this might be right for
pMMR/MSSLocally Advanced Rectal CarcinomaFasting, Intermittent
Zhejiang University 51
Not applicableUnknownNCT06364046
What this trial is testing

Efficacy and Safety of DEB-BACE Combined With Serplulimab in First-line Treatment of SCLC

Who this might be right for
CarcinomaSmall Cell Lung Cancer
The Central Hospital of Lishui City 56
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