Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Severe, Chronic Pain”

220 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 220 results

Post-approval studies (Phase 4)WithdrawnNCT01631513
What this trial is testing

An Open-label Evaluation of Tapentadol Extended Release (ER) in Participants With Moderate to Severe Chronic Pain After Conversion From Hydrocodone, Oxycodone Controlled Release (CR), and/or Morphine Sustained Release (SR)

Who this might be right for
PainChronic Back PainChronic Low Back Pain+1 more
Janssen Scientific Affairs, LLC
Not applicableStudy completedNCT03925168
What this trial is testing

Music Therapy and Dialysis: A Pilot Investigation Into the Effectiveness of Patient-Selected Music Interventions on Physiological, Psychological, and Quality-of-Life Outcomes

Who this might be right for
End Stage Renal DiseaseDepressionAnxiety+10 more
Tulane University 50
Testing effectiveness (Phase 2)Study completedNCT00929188
What this trial is testing

The Safety and Effectiveness of JNJ-42160443 as add-on Treatment in Patients With Cancer-related Pain

Who this might be right for
Pain, BurningPain, CrushingPain, Migratory+2 more
Janssen Research & Development, LLC 100
Large-scale testing (Phase 3)Study completedNCT01559701
What this trial is testing

Long-term Safety of PF-00345439 (Oxycodone)

Who this might be right for
Pain
Pain Therapeutics 823
Post-approval studies (Phase 4)Study completedNCT00576017
What this trial is testing

Evaluate the Safety and Effectiveness of Fentanyl-TTS Compared to Weak Opioids in Patients With Moderate to Severe Chronic Cancer Pain Previously Treated With NSAIDS (Non-steroidal Anti-inflammatory Drugs).

Who this might be right for
Pain
Janssen-Cilag, S.A. 19
Testing effectiveness (Phase 2)Study completedNCT02558439
What this trial is testing

Study to Evaluate the Safety and Efficacy of CNTX-4975 in Subjects With Chronic, Moderate to Severe Osteoarthritis Knee Pain

Who this might be right for
Osteoarthritis
Centrexion Therapeutics 175
Large-scale testing (Phase 3)Ended earlyNCT00982280
What this trial is testing

Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Pain Due to Osteoarthritis Taking WHO Step III Analgesics But Showing a Lack of Tolerability.

Who this might be right for
Chronic PainOsteoarthritis
Grünenthal GmbH 82
Large-scale testing (Phase 3)UnknownNCT01316744
What this trial is testing

Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain

Who this might be right for
Cancer
University of Glasgow 214
Not applicableStudy completedNCT00956475
What this trial is testing

Quality of Life in Younger Leukemia and Lymphoma Survivors

Who this might be right for
Anxiety DisorderCancer SurvivorFatigue+7 more
Case Comprehensive Cancer Center 48
Not applicableStudy completedNCT05848518
What this trial is testing

Exercise for Health in Patients With Post-acute Sequelae of COVID-19

Who this might be right for
Long COVID
Campus docent Sant Joan de Déu-Universitat de Barcelona 120
Not applicableLooking for participantsNCT05667090
What this trial is testing

Effects of Multiple Mega-dose of Vitamin D3 Supplementation on Ameliorating Moderate to Severe Chronic Pain in Hemodialysis Patients

Who this might be right for
HemodialysisChronic PainHyperparathyroidism
Taipei Medical University Hospital 120
Large-scale testing (Phase 3)Study completedNCT00313846
What this trial is testing

Safety and Efficacy of Buprenorphine Transdermal System in Subjects With Moderate to Severe Osteoarthritis of Hip or Knee

Who this might be right for
Osteoarthritis
Purdue Pharma LP 529
Post-approval studies (Phase 4)Study completedNCT01373983
What this trial is testing

Intrathecal Bolus Doses of Ziconotide

Who this might be right for
Peripheral Neuropathy
University Hospital, Linkoeping 26
Large-scale testing (Phase 3)Study completedNCT00348452
What this trial is testing

A Study Comparing the Effectiveness and Safety of Extended Release Tramadol HCl at 100 mg, 200 mg and 300 mg Doses to Placebo for the Treatment of Moderate to Severe Pain Due to Osteoarthritis (OA)

Who this might be right for
Chronic Pain
Bausch Health Americas, Inc. 1,000
Not applicableStudy completedNCT03713047
What this trial is testing

A National Center for Persistent Severe Pain After Groin Hernia Repair

Who this might be right for
Inguinal HerniaChronic Pain
University of Copenhagen 222
Large-scale testing (Phase 3)Study completedNCT03429049
What this trial is testing

Efficacy and Safety Study of Intra-articular CNTX-4975-05 (Capsaicin) vs Placebo in Subjects With OA Knee Pain

Who this might be right for
Osteoarthritis, Knee
Centrexion Therapeutics 332
Not applicableLooking for participantsNCT07485387
What this trial is testing

Global Collaborative Research on Establishing a Korean Cognitive Aging Cohort

Who this might be right for
Mild Cognitive Impairment (MCI)Dementia Alzheimer TypeChronic Pain+1 more
Korea University 180
Post-approval studies (Phase 4)Study completedNCT01961271
What this trial is testing

Evaluation Of Efficacy And Safety Of Norspan In Moderate To Severe Pain Due To Osteoarthritis, Rheumatoid Arthritis, Joint/Muscle Pain

Who this might be right for
OsteoarthritisRheumatoid ArthritisLower Back Pain+2 more
Mundipharma Pte Ltd. 114
Testing effectiveness (Phase 2)Ended earlyNCT03313076
What this trial is testing

Vitamin D and n-3 Polyunsaturated Fatty Acids (PUFAs) to Prevent Chronic Pain Following Major Thermal Burn Injury

Who this might be right for
Chronic Pain Following Thermal Burn Injury
University of North Carolina, Chapel Hill 24
Large-scale testing (Phase 3)UnknownNCT03967327
What this trial is testing

Evaluate Buprenorphine Transdermal Patch in Chinese Subjects With Moderate to Severe Chronic Cancer Pain

Who this might be right for
Cancer Pain
Mundipharma (China) Pharmaceutical Co. Ltd 194
Load More Results