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Results for “Severe Combined Immunodeficiencies (SCID)”

98 trials

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Showing 20 of 98 results

Testing effectiveness (Phase 2)WithdrawnNCT04370795
What this trial is testing

Matched Related and Unrelated Donor Stem Cell Transplantation for Severe Combined Immune Deficiency (SCID): Busulfan-based Conditioning With h-ATG, Radiation, and Sirolimus

Who this might be right for
Severe Combined Immune Deficiency (SCID)
National Institute of Allergy and Infectious Diseases (NIAID)
Testing effectiveness (Phase 2)Looking for participantsNCT03311503
What this trial is testing

Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning

Who this might be right for
Severe Combined Immunodeficiency, X LinkedGene Therapy
David Williams 12
Not applicableEnrolling By InvitationNCT00895271
What this trial is testing

Establishing Fibroblast-Derived Cell Lines From Skin Biopsies of Patients With Immunodeficiency or Immunodysregulation Disorders

Who this might be right for
Primary ImmunodeficiencyDOCK8Virus Susceptibility
National Institute of Allergy and Infectious Diseases (NIAID) 200
Not applicableUnknownNCT00006319
What this trial is testing

Molecular and Clinical Studies of Primary Immunodeficiency Diseases

Who this might be right for
Wiskott- Aldrich SyndromeADA Deficient SCID
National Human Genome Research Institute (NHGRI) 266
Testing effectiveness (Phase 2)Study completedNCT01380990
What this trial is testing

Lentiviral (LV) Gene Therapy for Adenosine Deaminase (ADA) Deficiency

Who this might be right for
Adenosine Deaminase DeficiencySevere Combined Immunodeficiencies (SCID)
Great Ormond Street Hospital for Children NHS Foundation Trust 36
Not applicableStudy completedNCT00695279
What this trial is testing

Long Term Follow Up Of Patients Who Have Received Gene Therapy Or Gene Marked Products

Who this might be right for
Severe Combined ImmunodeficiencyMalignancy, HematologicNeuroblastoma+2 more
St. Jude Children's Research Hospital 41
Large-scale testing (Phase 3)Study completedNCT03201003
What this trial is testing

ARTEMIS Peanut Allergy In Children

Who this might be right for
Peanut Allergy
Aimmune Therapeutics, Inc. 175
Not applicableLooking for participantsNCT00128973
What this trial is testing

Evaluation of Patients With Immune Function Abnormalities

Who this might be right for
Chronic Granulomatous Disease (CGD)X-Linked Severe Combined Immune Deficiency (XSCID)Leukocyte Adhesion Deficiency 1 (LAD)+1 more
National Institute of Allergy and Infectious Diseases (NIAID) 3,500
Not applicableLooking for participantsNCT06659588
What this trial is testing

Study of Populations at Risk of Developing Chronic Hepatitis Linked to Chronic Enteric Virus Infection in Patients With Primary Immunodeficiency and Secondary Humoral Deficiency

Who this might be right for
Humoral Primary Immunodeficiencies (PIDs)Secondary Form of Humoral ImmunodeficienciesCombined Immunodeficiency (CID)+1 more
Assistance Publique - Hôpitaux de Paris 120
Post-approval studies (Phase 4)WithdrawnNCT03311074
What this trial is testing

Retroviral Insertion Site Methodology Study

Who this might be right for
Immune System Diseases
Fondazione Telethon
Not applicableStudy completedNCT03232203
What this trial is testing

Evaluating the Effectiveness of STRIMVELIS Risk Minimization Measures (RMMs)

Who this might be right for
Severe Combined Immunodeficiency Due to ADA Deficiency
Fondazione Telethon 16
Testing effectiveness (Phase 2)UnknownNCT03315078
What this trial is testing

Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age With X-Linked Severe Combined Immunodeficiency

Who this might be right for
X-Linked Combined Immunodeficiency Diseases
National Institute of Allergy and Infectious Diseases (NIAID) 13
Testing effectiveness (Phase 2)Study completedNCT00794508
What this trial is testing

MND-ADA Transduction of CD34+ Cells From Children With ADA-SCID

Who this might be right for
Severe Combined Immunodeficiency
Donald B. Kohn, M.D. 10
Not applicableStudy completedNCT00043225
What this trial is testing

The Role of Bacteria and Genetic Variations in Cystic Fibrosis

Who this might be right for
Psuedomas InfectionCystic Fibrosis
National Heart, Lung, and Blood Institute (NHLBI) 76
Testing effectiveness (Phase 2)Looking for participantsNCT03217617
What this trial is testing

SCID-X1 Gene Therapy Via Intravenous Lentiviral (Ivlv-X1) Injection

Who this might be right for
SCID, X-Linked
Shenzhen Geno-Immune Medical Institute 10
Not applicableStudy completedNCT03878069
What this trial is testing

Registry Study of Revcovi Treatment in Patients With ADA-SCID

Who this might be right for
Adenosine Deaminase Severe Combined Immunodeficiency
Chiesi Farmaceutici S.p.A. 32
Early research (Phase 1)Looking for participantsNCT03601286
What this trial is testing

Lentiviral Gene Therapy for X-linked Severe Combined Immunodeficiency

Who this might be right for
Severe Combined Immunodeficiency, X-Linked
Great Ormond Street Hospital for Children NHS Foundation Trust 5
Testing effectiveness (Phase 2)Enrolling By InvitationNCT01852370
What this trial is testing

Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency Diseases

Who this might be right for
Severe Combined Immunodeficiency (SCID)Immunodeficiency With Predominant T-cell Defect, UnspecifiedSevere Chronic Neutropenia+6 more
Paul Szabolcs 16
Testing effectiveness (Phase 2)Looking for participantsNCT05432310
What this trial is testing

Gene Therapy for Adenosine Deaminase Severe Combined Immune Deficiency Using Peripheral Blood and EFS ADA Vector

Who this might be right for
Adenosine Deaminase Severe Combined Immune Deficiency
University of California, Los Angeles 20
Not applicableUnknownNCT05300373
What this trial is testing

Evaluation of Adenosine Deaminase (ADA) Enzyme Deficiency in Patients With Lymphopenia and/or Elevated Immunoglobulin E

Who this might be right for
Adenosine Deaminase Deficiency
TRPHARM 100
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