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Results for “Severe Combined Immunodeficiency Disease”

115 trials

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Showing 20 of 115 results

Testing effectiveness (Phase 2)WithdrawnNCT04370795
What this trial is testing

Matched Related and Unrelated Donor Stem Cell Transplantation for Severe Combined Immune Deficiency (SCID): Busulfan-based Conditioning With h-ATG, Radiation, and Sirolimus

Who this might be right for
Severe Combined Immune Deficiency (SCID)
National Institute of Allergy and Infectious Diseases (NIAID)
Testing effectiveness (Phase 2)Study completedNCT02999984
What this trial is testing

Efficacy and Safety of the Cryopreserved Formulation of OTL-101 in Subjects With ADA-SCID

Who this might be right for
Severe Combined Immunodeficiency Due to ADA Deficiency
University of California, Los Angeles 10
Large-scale testing (Phase 3)Study completedNCT00220766
What this trial is testing

Rapid Infusion of Immune Globulin Intravenous (Human) In Primary Immunodeficiency Patients

Who this might be right for
Immunologic Deficiency SyndromeAgammaglobulinemiaSevere Combined Immunodeficiency+2 more
Grifols Therapeutics LLC 100
Testing effectiveness (Phase 2)Enrolling By InvitationNCT01852370
What this trial is testing

Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency Diseases

Who this might be right for
Severe Combined Immunodeficiency (SCID)Immunodeficiency With Predominant T-cell Defect, UnspecifiedSevere Chronic Neutropenia+6 more
Paul Szabolcs 16
Testing effectiveness (Phase 2)Study completedNCT04996797
What this trial is testing

Safety and Efficacy Study of Tulisokibart (MK-7240/PRA023) in Subjects With Moderately to Severely Active Ulcerative Colitis (MK-7240-005)

Who this might be right for
Ulcerative Colitis
Prometheus Biosciences, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 178
Testing effectiveness (Phase 2)Study completedNCT00000801
What this trial is testing

Phase II Trial of Sequential Chemotherapy and Radiotherapy for AIDS-Related Primary Central Nervous System Lymphoma

Who this might be right for
Lymphoma, Non-HodgkinHIV Infections
National Institute of Allergy and Infectious Diseases (NIAID) 33
Not applicableStudy completedNCT00695279
What this trial is testing

Long Term Follow Up Of Patients Who Have Received Gene Therapy Or Gene Marked Products

Who this might be right for
Severe Combined ImmunodeficiencyMalignancy, HematologicNeuroblastoma+2 more
St. Jude Children's Research Hospital 41
Testing effectiveness (Phase 2)Study completedNCT01022476
What this trial is testing

Raltegravir in Patients With End Stage Liver Disease and in Transplant Recipients

Who this might be right for
HIV InfectionLiver FailureEvidence of Liver Transplantation
ANRS, Emerging Infectious Diseases 14
Testing effectiveness (Phase 2)Study completedNCT03765632
What this trial is testing

Efficacy and Safety of the Cryopreserved Formulation of OTL-101 in Subjects With ADA-SCID

Who this might be right for
Severe Combined Immunodeficiency Due to ADA Deficiency
Great Ormond Street Hospital for Children NHS Foundation Trust 13
Testing effectiveness (Phase 2)Study completedNCT01279720
What this trial is testing

Gene Therapy ADA Deficiency

Who this might be right for
Adenosine Deaminase Deficiency
Great Ormond Street Hospital for Children NHS Foundation Trust 8
Early research (Phase 1)Ended earlyNCT04409080
What this trial is testing

REGN7257 in Adult Patients With Severe Aplastic Anemia That Is Refractory to or Relapsed on Immunosuppressive Therapy

Who this might be right for
Severe Aplastic Anemia (SAA)
Regeneron Pharmaceuticals 17
Large-scale testing (Phase 3)Ended earlyNCT01390220
What this trial is testing

Study to Evaluate the Safety and Efficacy of USL261 (Intranasal Midazolam) in Patients With Seizure Clusters

Who this might be right for
Epilepsy
UCB Biopharma S.P.R.L. 292
Not applicableUnknownNCT05300373
What this trial is testing

Evaluation of Adenosine Deaminase (ADA) Enzyme Deficiency in Patients With Lymphopenia and/or Elevated Immunoglobulin E

Who this might be right for
Adenosine Deaminase Deficiency
TRPHARM 100
Not applicableUnknownNCT01175239
What this trial is testing

Gene Therapy for X-linked Severe Combined Immunodeficiency (SCID-X1)

Who this might be right for
X-linked Severe Combined Immunodeficiency
Great Ormond Street Hospital for Children NHS Foundation Trust 1
Not applicableWithdrawnNCT04331483
What this trial is testing

Assess a Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell Allografts

Who this might be right for
Haematological MalignancyAcute LeukemiaMyelodysplastic Syndromes+3 more
Centre Leon Berard
Large-scale testing (Phase 3)Study completedNCT00001013
What this trial is testing

Comparison of Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS

Who this might be right for
Pneumonia, Pneumocystis CariniiHIV Infections
National Institute of Allergy and Infectious Diseases (NIAID) 364
Not applicableWithdrawnNCT01182857
What this trial is testing

Quality of Life and Neuropsychiatric Sequelae in Patients Treated With Gene Therapy for ADA-SCID and in Their Parents

Who this might be right for
ADA-SCID
National Human Genome Research Institute (NHGRI)
Not applicableLooking for participantsNCT04528355
What this trial is testing

Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+2 more
Paul Szabolcs 50
Testing effectiveness (Phase 2)Ended earlyNCT02127892
What this trial is testing

SCID Bu/Flu/ATG Study With T Cell Depletion

Who this might be right for
Severe Combined Immunodeficiency
Neena Kapoor, M.D. 9
Large-scale testing (Phase 3)Study completedNCT01500616
What this trial is testing

Telaprevir Open-Label Study in Co-Infected Patients

Who this might be right for
Hepatitis C, Chronic
Janssen-Cilag International NV 122
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