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Results for “Severe Combined Immunodeficiency Syndrome”

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Showing 20 of 0 results

Not applicableUnknownNCT01175239
What this trial is testing

Gene Therapy for X-linked Severe Combined Immunodeficiency (SCID-X1)

Who this might be right for
X-linked Severe Combined Immunodeficiency
Great Ormond Street Hospital for Children NHS Foundation Trust 1
Testing effectiveness (Phase 2)Ended earlyNCT02357147
What this trial is testing

Study of the Safety and Efficacy of Amatuximab in Combination With Pemetrexed and Cisplatin in Subjects With Unresectable Malignant Pleural Mesothelioma (MPM)

Who this might be right for
Mesothelioma, Malignant
Morphotek 124
Not applicableUnknownNCT00596999
What this trial is testing

A Single-arm Safety Study of Transplantation Using Umbilical Cord Blood and Human Placental-derived Stem Cells From Partially Matched Related Donors in Persons With Certain Malignant Blood Diseases and Non-malignant Disorders

Who this might be right for
Hematologic Malignancies
Celgene Corporation 6
Not applicableStudy completedNCT00112593
What this trial is testing

Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Undifferentiated LeukemiaAdult Acute Lymphoblastic Leukemia in Remission+176 more
Fred Hutchinson Cancer Center 5
Not applicableUnknownNCT00006319
What this trial is testing

Molecular and Clinical Studies of Primary Immunodeficiency Diseases

Who this might be right for
Wiskott- Aldrich SyndromeADA Deficient SCID
National Human Genome Research Institute (NHGRI) 266
Testing effectiveness (Phase 2)Study completedNCT01129544
What this trial is testing

Gene Transfer for Severe Combined Immunodeficiency, X-linked (SCID-X1) Using a Self-inactivating (SIN) Gammaretroviral Vector

Who this might be right for
Severe Combined Immunodeficiency
David Williams 8
Not applicableUnknownNCT05300334
What this trial is testing

Investigation of ADA Enzyme Deficiency

Who this might be right for
Adenosine Deaminase Deficiency
TRPHARM 800
Testing effectiveness (Phase 2)Enrolling By InvitationNCT06851767
What this trial is testing

Base-Edited Hematopoietic Stem/Progenitor Cell X-Linked Severe Combined Immunodeficiency Gene Therapy

Who this might be right for
X-linked Severe Combined ImmunodeficiencyX-SCIDXSCID
National Institute of Allergy and Infectious Diseases (NIAID) 18
Early research (Phase 1)UnknownNCT02860559
What this trial is testing

Safety and Early Efficacy Study of TBX-1400 in Patients With Severe Combined Immunodeficiency

Who this might be right for
Severe Combined Immunodeficiency
Taiga Biotechnologies, Inc. 8
Testing effectiveness (Phase 2)Temporarily pausedNCT01512888
What this trial is testing

Gene Transfer for X-Linked Severe Combined Immunodeficiency in Newly Diagnosed Infants

Who this might be right for
Severe Combined Immunodeficiency Disease, X-linked
St. Jude Children's Research Hospital 28
Early research (Phase 1)Study completedNCT00018018
What this trial is testing

Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency

Who this might be right for
Severe Combined Immunodeficiency Syndrome
National Human Genome Research Institute (NHGRI) 8
Not applicableUnknownNCT04172181
What this trial is testing

Multi-center Clinical Study of Cord Blood Stem Cell Transplantation for SCID

Who this might be right for
Severe Combined Immunodeficiency Disease
Children's Hospital of Fudan University 50
Testing effectiveness (Phase 2)WithdrawnNCT04370795
What this trial is testing

Matched Related and Unrelated Donor Stem Cell Transplantation for Severe Combined Immune Deficiency (SCID): Busulfan-based Conditioning With h-ATG, Radiation, and Sirolimus

Who this might be right for
Severe Combined Immune Deficiency (SCID)
National Institute of Allergy and Infectious Diseases (NIAID)
Not applicableLooking for participantsNCT04528355
What this trial is testing

Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+2 more
Paul Szabolcs 50
Testing effectiveness (Phase 2)Looking for participantsNCT01962415
What this trial is testing

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+4 more
Paul Szabolcs 100
Large-scale testing (Phase 3)Study completedNCT01019876
What this trial is testing

Risk-Adapted Allogeneic Stem Cell Transplantation For Mixed Donor Chimerism In Patients With Non-Malignant Diseases

Who this might be right for
Bone Marrow FailureOsteopetrosisFanconi Anemia+1 more
Columbia University 38
Testing effectiveness (Phase 2)Active Not RecruitingNCT03597594
What this trial is testing

Haplocompatible Transplant Using TCRα/β Depletion Followed by CD45RA-Depleted Donor Lymphocyte Infusions for Severe Combined Immunodeficiency (SCID)

Who this might be right for
Severe Combined Immunodeficiency
St. Jude Children's Research Hospital 4
Not applicableUnknownNCT01346150
What this trial is testing

Patients Treated for SCID (1968-Present)

Who this might be right for
SCIDADA-SCIDXSCID+3 more
National Institute of Allergy and Infectious Diseases (NIAID) 1,007
Early research (Phase 1)Study completedNCT02022696
What this trial is testing

Treatment of SCID Due to ADA Deficiency With Autologous Transplantation of Cord Blood or Hematopoietic CD 34+ Cells After Addition of a Normal Human ADA cDNA by the EFS-ADA Lentiviral Vector

Who this might be right for
Adenosine Deaminase DeficiencyADA-SCID
National Human Genome Research Institute (NHGRI) 1
Testing effectiveness (Phase 2)Study completedNCT00794508
What this trial is testing

MND-ADA Transduction of CD34+ Cells From Children With ADA-SCID

Who this might be right for
Severe Combined Immunodeficiency
Donald B. Kohn, M.D. 10
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