Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Severe Hemophilia A”

288 trials

Showing 20 of 288 results

Not applicableStudy completedNCT02581969
What this trial is testing

Extension at 10 Years of the: "Observational Study Evaluating Efficacy and Costs of Secondary Prophylaxis vs On-demand Therapy With Kogenate Bayer in Patients With Severe Haemophilia A."

Who this might be right for
Hemophilia A
Bayer 43
Testing effectiveness (Phase 2)Study completedNCT02576795
What this trial is testing

Gene Therapy Study in Severe Haemophilia A Patients (270-201)

Who this might be right for
Severe Haemophilia A
BioMarin Pharmaceutical 15
Large-scale testing (Phase 3)Study completedNCT03417102
What this trial is testing

Fitusiran (ALN-AT3SC) in Severe Hemophilia A and B Patients With Inhibitors

Who this might be right for
Hemophilia AHemophilia B
Genzyme, a Sanofi Company 60
Post-approval studies (Phase 4)Study completedNCT00357656
What this trial is testing

Phase 3/4 Study of a Recombinant Protein-Free Factor VIII (rAHF-PFM): Comparison of Continuous Infusion Versus Intermittent Bolus Infusion in Hemophilia A Subjects Undergoing Major Orthopedic Surgery

Who this might be right for
Hemophilia A
Baxalta now part of Shire 85
Not applicableWithdrawnNCT01051544
What this trial is testing

Study of First TIME Immunotolerance Induction in Severe Hemophilia A Patients With Inhibitor at High Risk of Failure: Comparison With FVIII Concentrates With or Without Von Willebrand Factor - RES.I.S.T. Naive

Who this might be right for
Severe Hemophilia A
City of Hope Medical Center
Not applicableStudy completedNCT01000844
What this trial is testing

Joint Outcome Study Continuation for Children With Severe Factor VIII Deficiency

Who this might be right for
Hemophilia
University of Colorado, Denver 11
Early research (Phase 1)Study completedNCT04878731
What this trial is testing

Study to Evaluate Safety and Tolerability of a Single Dose of PF-06741086 in Chinese Adult Participants With Severe Hemophilia

Who this might be right for
Severe Hemophilia
Pfizer 6
Post-approval studies (Phase 4)Study completedNCT00092976
What this trial is testing

Study Evaluating ReFacto® in Hemophilia A Undergoing Major Surgery

Who this might be right for
Hemophilia A
Wyeth is now a wholly owned subsidiary of Pfizer 15
Post-approval studies (Phase 4)Study completedNCT03093480
What this trial is testing

Evaluate Efficacy of rFVIIIFc for Immune Tolerance Induction (ITI) in Severe Hemophilia A Participants With Inhibitors Undergoing the First ITI Treatment (verITI-8 Study)

Who this might be right for
Hemophilia A With Inhibitors
Bioverativ, a Sanofi company 16
Large-scale testing (Phase 3)UnknownNCT06155955
What this trial is testing

Comparison of Outcomes Between Low Dose Emicizumab and Factor VIII in Clinically Severe Hemophilia A

Who this might be right for
Severe Hemophilia A Without InhibitorJoint Bleed
Chulalongkorn University 15
Not applicableStudy completedNCT00195221
What this trial is testing

Study to Describe the Allergic Reactions to Factor IX in Patients With Hemophilia B

Who this might be right for
Hemophilia BAllergic Reactions
Wyeth is now a wholly owned subsidiary of Pfizer 166
Large-scale testing (Phase 3)Study completedNCT01913405
What this trial is testing

Phase 3 Efficacy and Safety Study of BAX 855 in Severe Hemophilia A Patients Undergoing Surgical Procedures

Who this might be right for
Hemophilia A
Baxalta now part of Shire 30
Testing effectiveness (Phase 2)Study completedNCT03370172
What this trial is testing

BAX 888 in Male Adults With Severe Hemophilia A

Who this might be right for
Hemophilia A
Baxalta now part of Shire 4
Not applicableStudy completedNCT00782470
What this trial is testing

Evaluation of the Reasons and Consequences of Bleeding in Late Teens and Early Adulthood Patients With Severe Hemophilia A

Who this might be right for
Hematologic DiseaseBlood Coagulation Disorders
Bayer 38
Large-scale testing (Phase 3)Study completedNCT01286779
What this trial is testing

BAX 326 (rFIX) Continuation Study

Who this might be right for
Hemophilia B
Baxalta now part of Shire 117
Post-approval studies (Phase 4)Active Not RecruitingNCT05181618
What this trial is testing

Evaluate Overall Health, Physical Activity, and Joint Outcomes in Participants With Severe or Moderate Hemophilia A Without Factor VIII Inhibitors on Emicizumab Prophylaxis

Who this might be right for
Severe Hemophilia AModerate Hemophilia A
Hoffmann-La Roche 136
Large-scale testing (Phase 3)Study completedNCT01233258
What this trial is testing

A Trial to Compare Prophylaxis Therapy to On-demand Therapy With a New Full Length Recombinant FVIII in Patients With Severe Hemophilia A

Who this might be right for
Hemophilia A
Bayer 80
Large-scale testing (Phase 3)Study completedNCT01125813
What this trial is testing

Efficacy and Safety Study of Human-cl rhFVIII in PTPs With Severe Hemophilia A

Who this might be right for
Severe Hemophilia A
Octapharma 32
Large-scale testing (Phase 3)Ended earlyNCT05695391
What this trial is testing

Safety and Efficacy of FVIIa to Prevent Excessive Bleeding in Hemophilia Patients With Inhibitors Undergoing Major Surgery

Who this might be right for
Hemophilia
Laboratoire français de Fractionnement et de Biotechnologies 2
Large-scale testing (Phase 3)Study completedNCT02615691
What this trial is testing

PEGylated Recombinant Factor VIII (BAX855) in Previously Untreated Young Children With Severe Hemophilia A

Who this might be right for
Hemophilia A
Baxalta now part of Shire 120
Next Page

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation