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Results for “Severe Hemophilia A Without Inhibitor”

19 trials

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Showing 19 of 19 results

Early research (Phase 1)Looking for participantsNCT06703606
What this trial is testing

Learn About How Changing Therapy From Emicizumab to Marstacimab Affects People With the Severe Hemophilia A.

Who this might be right for
Severe Hemophilia A
Pfizer 15
Not applicableStudy completedNCT04165135
What this trial is testing

An Observational Study to Evaluate Physical Activity, Bleeding Incidence and Health Related Quality of Life, in Participants With Haemophilia A Without Inhibitors Receiving Standard of Care Treatment

Who this might be right for
Severe Hereditary Factor VIII Deficiency Disease Without InhibitorModerate Hereditary Factor VIII Deficiency Disease Without InhibitorHaemophilia A
Hoffmann-La Roche 103
Testing effectiveness (Phase 2)UnknownNCT04592692
What this trial is testing

A Pharmacokinetic and Clotting Activity Study of FVIII-PEGLip

Who this might be right for
Hemophilia A With Inhibitor
Ascension Healthcare Development Limited 20
Large-scale testing (Phase 3)Study completedNCT03938792
What this trial is testing

Study of the Efficacy and Safety PF-06741086 in Adult and Teenage Participants With Severe Hemophilia A or Moderately Severe to Severe Hemophilia B

Who this might be right for
Hemophilia AHemophilia B
Pfizer 189
Not applicableLooking for participantsNCT05802836
What this trial is testing

Dynamics of the Anti-factor VIII Antibody Signature During Treatment With Emicizumab

Who this might be right for
Severe Hemophilia ASevere Hemophilia A With InhibitorSevere Hemophilia A Without Inhibitor
Christoph Königs 100
Large-scale testing (Phase 3)Looking for participantsNCT05145127
What this trial is testing

Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without Inhibitors

Who this might be right for
Hemophilia AHemophilia B
Pfizer 245
Post-approval studies (Phase 4)Looking for participantsNCT06320626
What this trial is testing

Pharmacokinetic-guided Dosing of Emicizumab

Who this might be right for
Hemophilia A With InhibitorHemophilia A Without InhibitorHemophilia A, Severe+3 more
Kathelijn Fischer 95
Large-scale testing (Phase 3)Looking for participantsNCT06155955
What this trial is testing

Comparison of Outcomes Between Low Dose Emicizumab and Factor VIII in Clinically Severe Hemophilia A

Who this might be right for
Severe Hemophilia A Without InhibitorJoint Bleed
Chulalongkorn University 15
Large-scale testing (Phase 3)Looking for participantsNCT05611801
What this trial is testing

A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B

Who this might be right for
Hemophilia AHemophilia B
Pfizer 100
Not applicableLooking for participantsNCT07096349
What this trial is testing

Multidimensional Assessment of Chronic Pain in Severe Haemophilia A

Who this might be right for
Hemophilia A Without Inhibitor
Investigación en Hemofilia y Fisioterapia 109
Testing effectiveness (Phase 2)Ended earlyNCT04541628
What this trial is testing

Safety & Efficacy of Encapsulated Allogeneic FVIII Cell Therapy in Haemophilia A

Who this might be right for
Hemophilia A
Eli Lilly and Company 3
Testing effectiveness (Phase 2)Study completedNCT03196297
What this trial is testing

A Trial Evaluating Efficacy and Safety of Prophylactic Administration of Concizumab in Patients With Severe Haemophilia A Without Inhibitors

Who this might be right for
HaemostasisHaemophilia A
Novo Nordisk A/S 36
Not applicableStudy completedNCT04181697
What this trial is testing

HemFitBit, an Observational Study of Physical Activity in People With Moderate and Severe Haemophilia A

Who this might be right for
Hemophilia A Without Inhibitor
Oslo University Hospital 40
Large-scale testing (Phase 3)Active Not RecruitingNCT04431726
What this trial is testing

Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Subcutaneous Emicizumab in Participants From Birth to 12 Months of Age With Hemophilia A Without Inhibitors

Who this might be right for
Severe Hemophilia A
Hoffmann-La Roche 55
Not applicableLooking for participantsNCT05981274
What this trial is testing

A Study on the Bone-health Effectiveness of Applying Recombinant Factor VIII Fc (rFVIIIFc) to Patients With Hemophilia A (Prototype A)

Who this might be right for
Severe Hemophilia A Without Inhibitor
Tri-Service General Hospital 45
Not applicableStudy completedNCT01051076
What this trial is testing

Rescue Immunotolerance Study in Induction of Immune Tolerance (ITI)-Experienced Patients (RES.I.S.T. Experienced)

Who this might be right for
Severe Hemophilia A
City of Hope Medical Center 3
Not applicableWithdrawnNCT01051544
What this trial is testing

Study of First TIME Immunotolerance Induction in Severe Hemophilia A Patients With Inhibitor at High Risk of Failure: Comparison With FVIII Concentrates With or Without Von Willebrand Factor - RES.I.S.T. Naive

Who this might be right for
Severe Hemophilia A
City of Hope Medical Center
Post-approval studies (Phase 4)Study completedNCT05281185
What this trial is testing

Clinical Outcomes of Low Dose PK-guided EHL FVIII Concentrates Versus Standard Prophylaxis in Severe Haemophilia A

Who this might be right for
Severe Hemophilia A Without Inhibitor
Chulalongkorn University 15
Large-scale testing (Phase 3)Ended earlyNCT04303559
What this trial is testing

The Hemophilia Inhibitor Prevention Trial

Who this might be right for
Hemophilia A Without Inhibitor
Margaret Ragni 1