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Results for “Severe Hypercholesterolemia”

31 trials

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Showing 20 of 31 results

Large-scale testing (Phase 3)Study completedNCT01764633
What this trial is testing

Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk

Who this might be right for
Dyslipidemia
Amgen 27,564
Large-scale testing (Phase 3)Study completedNCT02476006
What this trial is testing

Safety, Tolerability, and Effect of Alirocumab in High Cardiovascular Risk Patients With Severe Hypercholesterolemia Not Adequately Controlled With Conventional Lipid-modifying Therapies (ODYSSEY APPRISE)

Who this might be right for
Hypercholesterolemia
Sanofi 998
Not applicableStudy completedNCT03881657
What this trial is testing

Reverse Colocated Integrated Care Intervention Among Persons With Severe Persistent Mental Illness at US-Mexico Border

Who this might be right for
Mental Illness PersistentChronic DiseaseHypertension+4 more
Health Resources in Action, Inc. 416
Large-scale testing (Phase 3)Study completedNCT02624869
What this trial is testing

Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Cholesterol (Familial Hypercholesterolemia)

Who this might be right for
Familial Hypercholesterolemia
Amgen 163
Large-scale testing (Phase 3)Study completedNCT01598948
What this trial is testing

Effect of Mipomersen on LDL-Cholesterol Levels in Patients Treated by Regular Apheresis

Who this might be right for
AtherosclerosisLDL-hypercholesterolemia
Ludwig-Maximilians - University of Munich 17
Not applicableStudy completedNCT06045377
What this trial is testing

Effect of Armolipid on Lipid Profile in Children With Hypercholesterolemia

Who this might be right for
DyslipidemiasChildren, Only
Athens General Children's Hospital "Pan. & Aglaia Kyriakou" 90
Large-scale testing (Phase 3)Active Not RecruitingNCT05739383
What this trial is testing

Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.

Who this might be right for
Primary Prevention of Atherosclerotic Cardiovascular Disease
Novartis Pharmaceuticals 14,082
Not applicableTemporarily pausedNCT04031469
What this trial is testing

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease

Who this might be right for
Gut MicrobiomeGastrointestinal MicrobiomeAutism+77 more
ProgenaBiome 1,000
Large-scale testing (Phase 3)Study completedNCT02585895
What this trial is testing

Evolocumab Compared to LDL-C Apheresis in Patients Receiving LDL-C Apheresis Prior to Study Enrollment

Who this might be right for
Hypercholesterolemia
Amgen 39
Not applicableUnknownNCT04087915
What this trial is testing

Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With High Risk Coronary Artery Disease (FORWARD)

Who this might be right for
DyslipidemiaHigh Risk Coronary Artery Disease
Beijing Anzhen Hospital 1,000
Not applicableStudy completedNCT04481737
What this trial is testing

Peer-delivered and Technology-Assisted Integrated Illness Management and Recovery

Who this might be right for
SchizophreniaBipolar DisorderMajor Depressive Disorder, Recurrent+6 more
Dartmouth-Hitchcock Medical Center 40
Not applicableUnknownNCT03428308
What this trial is testing

Detection and Treatment of Somatic Disease in Patients With Severe Mental Disease

Who this might be right for
IschemiaCardiac InsufficiencyDiabetes Mellitus, Type 2+3 more
Intersectoral Research Unit for Health Services 90
Not applicableTemporarily pausedNCT05218304
What this trial is testing

Baromètre Santé Adulte 2021-2022

Who this might be right for
DiabetesHypercholesterolemiaRenal Failure+7 more
Agence Sanitaire et Sociale de Nouvelle Calédonie 5,471
Post-approval studies (Phase 4)Study completedNCT00405171
What this trial is testing

Efavirenz to Nevirapine Switch and Low-Density Lipoprotein (LDL)-Dyslipidemia

Who this might be right for
HIV InfectionsHypercholesterolemiaAntiretroviral Therapy
University Hospital, Caen 40
Large-scale testing (Phase 3)Study completedNCT00694109
What this trial is testing

An Open-label Extension Study to Assess the Long-term Safety and Efficacy of ISIS 301012 (Mipomersen) in Patients With Familial Hypercholesterolemia or Severe-Hypercholesterolemia

Who this might be right for
Lipid Metabolism, Inborn ErrorsHypercholesterolemia, Autosomal DominantHyperlipidemias+11 more
Kastle Therapeutics, LLC 144
Large-scale testing (Phase 3)Active Not RecruitingNCT05030428
What this trial is testing

Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease

Who this might be right for
Atherosclerotic Cardiovascular Disease
Novartis Pharmaceuticals 17,004
Post-approval studies (Phase 4)Study completedNCT02098460
What this trial is testing

To Compare the Effect of Concomitant Administration of Probucol and Cilostazol With Probucol Single Treatment on the Atherosclerosis Related Markers (Including the Thickness of the Achilles Tendon) and Evaluate Safety (Based on Atorvastatin Treatment) in Severe Hypercholesterolemia Subject

Who this might be right for
Severe Hypercholesterolemia
Otsuka Beijing Research Institute 300
Large-scale testing (Phase 3)Study completedNCT01624142
What this trial is testing

Trial Assessing Long Term USe of PCSK9 Inhibition in Subjects With Genetic LDL Disorders

Who this might be right for
Severe Familial Hypercholesterolemia
Amgen 300
Testing effectiveness (Phase 2)Study completedNCT03110848
What this trial is testing

Effects of Atorvastatin in Graves' Orbitopathy (GO)

Who this might be right for
Thyroid Associated OphthalmopathyHypercholesterolemia
University of Pisa 88
Post-approval studies (Phase 4)Looking for participantsNCT06909565
What this trial is testing

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

Who this might be right for
Percutaneous Coronary InterventionPeripheral Endovascular Intervention
Duke University 6,000
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