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Results for “Severe Immunosuppression”

47 trials

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Showing 20 of 47 results

Testing effectiveness (Phase 2)Study completedNCT00065260
What this trial is testing

Rabbit Antithymocyte Globulin Versus Campath-1H for Treating Severe Aplastic Anemia

Who this might be right for
Aplastic Anemia
National Heart, Lung, and Blood Institute (NHLBI) 54
Testing effectiveness (Phase 2)Study completedNCT00195624
What this trial is testing

Alemtuzumab to Treat Severe Aplastic Anemia

Who this might be right for
Severe Aplastic Anemia, RefractorySevere Aplastic Anemia, Relapse
National Heart, Lung, and Blood Institute (NHLBI) 47
Large-scale testing (Phase 3)Ended earlyNCT01408836
What this trial is testing

Plasma Exchange for Renal Vasculitis

Who this might be right for
Wegener's GranulomatosisMicroscopic Polyangiitis
Cambridge University Hospitals NHS Foundation Trust 150
Early research (Phase 1)Study completedNCT01917708
What this trial is testing

Bone Marrow Transplant With Abatacept for Non-Malignant Diseases

Who this might be right for
Hurler SyndromeFanconi AnemiaGlanzmann Thrombasthenia+12 more
Emory University 10
Testing effectiveness (Phase 2)Study completedNCT00002657
What this trial is testing

SWOG-9239 Reduction of Immunosuppression Plus Interferon Alfa and Combination Chemotherapy in Treating Patients With Malignant Tumors That Develop After Organ Transplant

Who this might be right for
LymphomaMultiple Myeloma and Plasma Cell Neoplasm
SWOG Cancer Research Network 20
Not applicableActive Not RecruitingNCT07816471
What this trial is testing

RSV, Influenza, and SARS-CoV-2 Outcomes in Severely Immunosuppressed Adults

Who this might be right for
Respiratory Syncytial Virus InfectionsImmunocompromised HostInfluenza+1 more
Hospital Italiano de Buenos Aires 350
Testing effectiveness (Phase 2)Study completedNCT00001034
What this trial is testing

The Safety and Effectiveness of Ganciclovir in the Prevention of Cytomegalovirus (CMV) of the Eyes and Disease of the Stomach and Intestines in Patients With HIV

Who this might be right for
Cytomegalovirus RetinitisHIV InfectionsGastrointestinal Diseases
National Institute of Allergy and Infectious Diseases (NIAID) 850
Testing effectiveness (Phase 2)Study completedNCT00001964
What this trial is testing

Combination Therapy of Severe Aplastic Anemia

Who this might be right for
Severe Aplastic Anemia
National Heart, Lung, and Blood Institute (NHLBI) 104
Very early researchWithdrawnNCT04776850
What this trial is testing

Pre-transplant Immunosuppression and Donor Stem Cell Transplant for the Treatment of Severe Hemoglobinopathies

Who this might be right for
Beta Thalassemia MajorSickle Beta 0 ThalassemiaSickle Beta Plus Thalassemia+3 more
M.D. Anderson Cancer Center
Early research (Phase 1)Study completedNCT00255710
What this trial is testing

Cyclophosphamide and/or Mycophenolate Mofetil With or Without Tacrolimus in Treating Patients Who Are Undergoing a Donor Bone Marrow or Peripheral Stem Cell Transplant for Hematologic Cancer

Who this might be right for
Chronic Myeloproliferative DisordersGraft Versus Host DiseaseLeukemia+4 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 60
Large-scale testing (Phase 3)Looking for participantsNCT06059989
What this trial is testing

InDuctIon TREatment with SubCuTaneous Infliximab for Crohn's Disease

Who this might be right for
Inflammatory DiseaseDisease CrohnBowel Disease
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 158
Testing effectiveness (Phase 2)Study completedNCT00006251
What this trial is testing

Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic Cancer

Who this might be right for
Acute Undifferentiated LeukemiaAdult Nasal Type Extranodal NK/T-cell LymphomaAnaplastic Large Cell Lymphoma+61 more
Fred Hutchinson Cancer Center 21
Testing effectiveness (Phase 2)Study completedNCT00089011
What this trial is testing

Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant for Hematologic Cancer

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Myeloid Leukemia in Remission+171 more
Fred Hutchinson Cancer Center 150
Testing effectiveness (Phase 2)UnknownNCT03024957
What this trial is testing

Effect of Intrathecal Morphine, Dexmedetomidine or Both in Combination to Bupivacaine on Immunity

Who this might be right for
Immune System Suppression
Assiut University 30
Not applicableStudy completedNCT00112593
What this trial is testing

Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Undifferentiated LeukemiaAdult Acute Lymphoblastic Leukemia in Remission+176 more
Fred Hutchinson Cancer Center 5
Testing effectiveness (Phase 2)UnknownNCT00740467
What this trial is testing

Stem Cell Transplant in Treating Patients With Hematological Cancer or Other Disorders

Who this might be right for
Graft Versus Host DiseaseLeukemiaLymphoma+2 more
Institut Paoli-Calmettes 50
Testing effectiveness (Phase 2)Study completedNCT01187017
What this trial is testing

A Pilot Study of Fludarabine Plus Cyclophosphamide in Refractory Severe Aplastic Anemia

Who this might be right for
Aplastic AnemiaNeutropeniaPancytopenia+1 more
National Heart, Lung, and Blood Institute (NHLBI) 1
Not applicableLooking for participantsNCT07184853
What this trial is testing

Ruxolitinib Plus Etanercept vs Ruxolitinib for Steroid-Refractory Severe Acute GVHD

Who this might be right for
Graft vs Host Disease
First Affiliated Hospital of Zhejiang University 122
Testing effectiveness (Phase 2)Study completedNCT01193283
What this trial is testing

Cyclophosphamide Plus Cyclosporine in Treatment-Naive Severe Aplastic Anemia

Who this might be right for
Aplastic AnemiaNeutropeniaPancytopenia+1 more
National Heart, Lung, and Blood Institute (NHLBI) 22
Testing effectiveness (Phase 2)Study completedNCT00049504
What this trial is testing

Haploidentical Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancer

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Myeloid Leukemia in Remission+94 more
Fred Hutchinson Cancer Center 53
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