Not applicableStudy completedNCT01257477What this trial is testingLOTRONEX® in Severe Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D)Who this might be right forIrritable Bowel Syndrome Prometheus Laboratories 400
Not applicableLooking for participantsNCT06869928What this trial is testingImplementation of the Pain and Irritability of Unknown Origin (PIUO) Pathway in Community Pediatric PracticesWho this might be right forPainIrritabilityNeuropathic Pain University of British Columbia 20
Large-scale testing (Phase 3)Study completedNCT03318614What this trial is testingBifidobacterium Infantis M-63 Improves Mental Health in Irritable Bowel Syndrome Developed After a Major Flood DisasterWho this might be right forIrritable Bowel SyndromeAbdominal PainSmall Intestinal Bacterial Overgrowth Universiti Sains Malaysia 53
Post-approval studies (Phase 4)Ended earlyNCT01337609What this trial is testingStudy of Probiotic GanedenBC30 for Irritable Bowel Syndrome and Major Depressive DisorderWho this might be right forMajor Depressive DisorderIrritable Bowel Syndrome Massachusetts General Hospital 5
Not applicableWithdrawnNCT05357495What this trial is testingCharacterization and Brain Mechanisms of Frustration in Youth With Severe Irritability or Attention Deficit Hyperactivity Disorder (ADHD)Who this might be right forDisruptive Mood Dysregulation DisorderAttention Deficit Hyperactivity DisorderNormal Physiology National Institute of Mental Health (NIMH)
Large-scale testing (Phase 3)WithdrawnNCT02212613What this trial is testingBrexpiprazole (OPC 34712) Trial in the Treatment of Adults With Major Depressive Disorder and IrritabilityWho this might be right forMajor Depressive Disorder and Irritability Otsuka Pharmaceutical Development & Commercialization, Inc.
Large-scale testing (Phase 3)Looking for participantsNCT05120752What this trial is testingEfficacy of a Low FODMAP Diet in the Absence of Lactose Malabsorption in Moderate to Severe ROME IV IBS.Who this might be right forIrritable Bowel Syndrome Universitair Ziekenhuis Brussel 60
Post-approval studies (Phase 4)UnknownNCT04454996What this trial is testingStudy on the Rule and Mechanism of Treating Functional Gastrointestinal Diseases From the Perspective of Liver and SpleenWho this might be right forNon-erosive Reflux Disease/Diarrheal Irritable Bowel Syndrome Xiyuan Hospital of China Academy of Chinese Medical Sciences 100
Large-scale testing (Phase 3)Study completedNCT01942785What this trial is testingStudy of Brexpiprazole as Adjunctive Treatment of Irritability in Patients With Major Depressive Disorder and an Inadequate Response to Antidepressant TherapyWho this might be right forMajor Depressive DisorderIrritability H. Lundbeck A/S 55
Early research (Phase 1)Not Yet RecruitingNCT07452692What this trial is testingAssess the Skin Irritation and Sensitization of Selegiline TDS in Healthy SubjectsWho this might be right forMajor Depressive Disorder (MDD) Corium Innovations, Inc. 230
Very early researchNot Yet RecruitingNCT06760533What this trial is testingPsilocybin-Assisted Psychotherapy in Treating Irritable Bowel Syndrome (IBS)Who this might be right forIBS - Irritable Bowel Syndrome NYU Langone Health 10
Large-scale testing (Phase 3)Active Not RecruitingNCT05174273What this trial is testingNeurocognitive Effects of FMT in MDD Patients With and Without IBSWho this might be right forMajor Depressive DisorderIrritable Bowel Syndrome Valerie Taylor 133
Post-approval studies (Phase 4)Study completedNCT02078596What this trial is testingDepakote (Divalproex Sodium) for Children With Temper Dysregulation and Severe Mood SwingsWho this might be right forIrritable Aggression New York State Psychiatric Institute 15
Not applicableLooking for participantsNCT05274854What this trial is testingA Practice Change for Patients With Severe Chronic, Clinically Unexplained Gastrointestinal SymptomsWho this might be right forGastrointestinal DiseasesIrritable Bowel Syndrome The University of Queensland 200
Post-approval studies (Phase 4)Study completedNCT01464229What this trial is testingIloperidone Augmentation of SSRIs for Patients With Major Depressive Disorder With Residual Anger and IrritabilityWho this might be right forMajor Depressive Disorder Maurizio Fava, MD 20
Not applicableLooking for participantsNCT02531893What this trial is testingPsychological Treatments for Youth With Severe Irritability.Who this might be right forIrritability National Institute of Mental Health (NIMH) 200
Not applicableTemporarily pausedNCT04031469What this trial is testingA Non-Interventional Pilot Study to Explore the Role of Gut Flora in DiseaseWho this might be right forGut MicrobiomeGastrointestinal MicrobiomeAutism+77 more ProgenaBiome 1,000
Testing effectiveness (Phase 2)Study completedNCT01887834What this trial is testingEfficacy of a Multi-strain Probiotic in the Treatment of Irritable Bowel SyndromeWho this might be right forIrritable Bowel SyndromeDigestive System DiseasesColonic Diseases, Functional+2 more The Canadian College of Naturopathic Medicine 100
Not applicableStudy completedNCT04037826What this trial is testingL. Reuteri DSM 17938 and L. Reuteri ATCC PTA 6475 in Moderate to Severe Irritable Bowel in AdultsWho this might be right forIrritable Bowel Syndrome Innovacion y Desarrollo de Estrategias en Salud 140
Large-scale testing (Phase 3)Study completedNCT02210689What this trial is testingA Multi-center, Double-blind, Randomized Study, Comparing Clindamycin Phosphate Vaginal Cream 2% (Watson Laboratories, Inc.) to Clindesse® (Ther-Rx™, Clindamyin Phosphate Vaginal Cream 2%) and Both Active Treatments to a Placebo Control in the Treatment of Bacterial Vaginosis in Non-pregnant WomenWho this might be right forBACTERIAL VAGINOSISSigns and Symptoms to be Evaluated and Recorded IncludeVaginal Discharge Color, Odor, and Consistency+2 more Actavis Inc. 604