Not applicableStudy completedNCT01257477What this trial is testingLOTRONEX® in Severe Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D)Who this might be right forIrritable Bowel Syndrome Prometheus Laboratories 400
Early research (Phase 1)Active Not RecruitingNCT07452692What this trial is testingAssess the Skin Irritation and Sensitization of Selegiline TDS in Healthy SubjectsWho this might be right forMajor Depressive Disorder (MDD) Corium Innovations, Inc. 232
Large-scale testing (Phase 3)WithdrawnNCT02212613What this trial is testingBrexpiprazole (OPC 34712) Trial in the Treatment of Adults With Major Depressive Disorder and IrritabilityWho this might be right forMajor Depressive Disorder and Irritability Otsuka Pharmaceutical Development & Commercialization, Inc.
Post-approval studies (Phase 4)Ended earlyNCT01337609What this trial is testingStudy of Probiotic GanedenBC30 for Irritable Bowel Syndrome and Major Depressive DisorderWho this might be right forMajor Depressive DisorderIrritable Bowel Syndrome Massachusetts General Hospital 5
Not applicableStudy completedNCT06346847What this trial is testingStudy to Assess Effects of Postbiotic vs Placebo in Participants With Diarrhea-predominant IBSWho this might be right forDiarrhea-Predominant Irritable Bowel Syndrome A-Mansia Biotech S.A. 384
Large-scale testing (Phase 3)Not Yet RecruitingNCT06433180What this trial is testingStudy of Fecal Microbiota Transplantation (FMT) in Severe IBS PatientsWho this might be right forIrritable Bowel Syndrome Assistance Publique - Hôpitaux de Paris 150
Large-scale testing (Phase 3)Active Not RecruitingNCT05174273What this trial is testingNeurocognitive Effects of FMT in MDD Patients With and Without IBSWho this might be right forMajor Depressive DisorderIrritable Bowel Syndrome Valerie Taylor 133
Not applicableStudy completedNCT03464773What this trial is testingPain and Irritability in Non-Verbal ChildrenWho this might be right forPainNeuropathic PainIrritability University of British Columbia 72
Not applicableStudy completedNCT04037826What this trial is testingL. Reuteri DSM 17938 and L. Reuteri ATCC PTA 6475 in Moderate to Severe Irritable Bowel in AdultsWho this might be right forIrritable Bowel Syndrome Innovacion y Desarrollo de Estrategias en Salud 140
Post-approval studies (Phase 4)Study completedNCT02078596What this trial is testingDepakote (Divalproex Sodium) for Children With Temper Dysregulation and Severe Mood SwingsWho this might be right forIrritable Aggression New York State Psychiatric Institute 15
Post-approval studies (Phase 4)Not Yet RecruitingNCT07544966What this trial is testingTeen Vulnerability to Irritability: Brain and Estrogen ChangesWho this might be right forDepression - Major Depressive DisorderIrritability University of North Carolina, Chapel Hill 50
Very early researchNot Yet RecruitingNCT06760533What this trial is testingPsilocybin-Assisted Psychotherapy in Treating Irritable Bowel Syndrome (IBS)Who this might be right forIBS - Irritable Bowel Syndrome NYU Langone Health 10
Not applicableStudy completedNCT01962623What this trial is testingInterpersonal Psychotherapy for Youth With Severe Mood DysregulationWho this might be right forSevere Mood Dysregulation Johns Hopkins University 31
Testing effectiveness (Phase 2)Study completedNCT05046184What this trial is testingElucidating the Neurocircuitry of Irritability With High-Field Neuroimaging to Identify Novel Therapeutic TargetsWho this might be right forMajor Depressive DisorderHealthy Controls University of Texas Southwestern Medical Center 165
Not applicableUnknownNCT05049356What this trial is testingSymptoms and Mechanisms of Child Psychiatric DisordersWho this might be right forDisruptive Mood Dysregulation DisorderAttention Deficit Hyperactivity DisorderOppositional Defiant Disorder+2 more Oslo University Hospital 218
Not applicableStudy completedNCT03238118What this trial is testingAttention Bias Modification, Attention Control and Psychoeducation for Irritability in Children and AdolescentsWho this might be right forIrritability Hospital de Clinicas de Porto Alegre 140
Not applicableLooking for participantsNCT02531893What this trial is testingPsychological Treatments for Youth With Severe Irritability.Who this might be right forIrritability National Institute of Mental Health (NIMH) 200
Large-scale testing (Phase 3)Study completedNCT01942785What this trial is testingStudy of Brexpiprazole as Adjunctive Treatment of Irritability in Patients With Major Depressive Disorder and an Inadequate Response to Antidepressant TherapyWho this might be right forMajor Depressive DisorderIrritability H. Lundbeck A/S 55
Large-scale testing (Phase 3)Looking for participantsNCT04974593What this trial is testingPredictive Value of Hydrogen/Methane Lactose Breath Testing on the Therapeutic Effect of Lactose-free Diet in Moderate to Severe ROME IV IBS.Who this might be right forIrritable Bowel SyndromeLactose Intolerant Universitair Ziekenhuis Brussel 90
Post-approval studies (Phase 4)Study completedNCT01754493What this trial is testingOpen Trial of Duloxetine in Outpatients With Irritable Bowel Syndrome Symptoms and Co-Morbid Major DepressionWho this might be right forMajor DepressionIrritable Bowel Syndrome New York State Psychiatric Institute 17