Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Severe Mental Disorders”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Post-approval studies (Phase 4)Looking for participantsNCT05892744
What this trial is testing

Establishing Multimodal Brain Biomarkers for Treatment Selection in Depression

Who this might be right for
Major Depressive DisorderChronic Major Depression, Recurrent
University of Texas at Austin 50
Post-approval studies (Phase 4)Study completedNCT00922064
What this trial is testing

Effects of Electroconvulsive Therapy (ECT) on Serotonin-1A Receptor Binding

Who this might be right for
Unipolar Depression
Medical University of Vienna 12
Large-scale testing (Phase 3)Study completedNCT01370499
What this trial is testing

LY2216684 in Participants With Major Depression Disorder

Who this might be right for
Major Depressive Disorder
Eli Lilly and Company 288
Post-approval studies (Phase 4)Study completedNCT00536471
What this trial is testing

A Study Comparing Duloxetine and Placebo in Assessing Energy and Vitality in Major Depressive Disorder (MDD) Patients

Who this might be right for
Major Depressive Disorder
Eli Lilly and Company 776
Not applicableStudy completedNCT02811198
What this trial is testing

Pain, Reward, Attention and Neurocircuitry: Biomarkers of Suicidality

Who this might be right for
Major Depressive DisorderSuicideSuicidal Ideation
Unity Health Toronto 97
Large-scale testing (Phase 3)Ended earlyNCT00857233
What this trial is testing

Safety and Tolerability of Memantine in Moderate to Severe Alzheimer's Disease

Who this might be right for
Alzheimer's Disease
H. Lundbeck A/S 297
Post-approval studies (Phase 4)Study completedNCT02058693
What this trial is testing

Adjunctive Mixed Salts Amphetamine for Depressed Adults With Incomplete Response to Current Antidepressant Therapy

Who this might be right for
Major Depressive Disorder
Rush University Medical Center 41
Not applicableLooking for participantsNCT06732284
What this trial is testing

Study of Sleep Inertia in Major Depressive Disorder by the Psychomotor Vigilance Task

Who this might be right for
Major DepressionSleep Inertia
Centre Hospitalier Universitaire de Nīmes 110
Large-scale testing (Phase 3)Study completedNCT00035009
What this trial is testing

Treatment of Patients With Major Depressive Disorder With MK0869 (0869-059)

Who this might be right for
Major Depressive Disorder
Merck Sharp & Dohme LLC 468
Testing effectiveness (Phase 2)Looking for participantsNCT05232032
What this trial is testing

Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Pharmacological Manipulation

Who this might be right for
Depressive Disorder, MajorAnxiety Disorder
Mclean Hospital 112
Not applicableStudy completedNCT01882452
What this trial is testing

A Randomised Controlled Clinical Trial of Memory Specificity Training (MEST) for Depression

Who this might be right for
Major Depressive DisorderDepressive Symptoms
Medical Research Council 60
Not applicableStudy completedNCT06641986
What this trial is testing

A Prediction Model of Postoperative Anxiety Symptom in Elderly Patients Undergoing Major Noncardiac Surgery

Who this might be right for
Predictive Model
Chinese PLA General Hospital 5,551
Not applicableStudy completedNCT07273851
What this trial is testing

Comparison of Propofol and Ketofol as Induction Agents for Electroconvulsive Therapy

Who this might be right for
Major Depressive Disorder
Fauji Foundation Hospital 80
Not applicableUnknownNCT04199845
What this trial is testing

8-week of PS128 RCT in Patients With Major Depressive Disorder

Who this might be right for
Major Depressive Disorder
Taipei Medical University WanFang Hospital 60
Post-approval studies (Phase 4)Study completedNCT00229645
What this trial is testing

A Double Blind, Randomized Placebo Controlled Study of the Efficacy, Safety and of Quetiapine Fumarate (Seroquel®) as Potentiation SSRI's, and SNRI's Treatment in Major Depression With Anxiety

Who this might be right for
Major Depression With Comorbid Anxiety Symptoms
Dr Alexander McIntyre Inc. 60
Not applicableUnknownNCT02409173
What this trial is testing

NPPV on Inflammatory Markers and Sleep in Severe Obese Patients With Metabolic Syndrome Undergone to Bariatric Surgery

Who this might be right for
Metabolic Syndrome
Centro Universitário de Anapolis 17
Not applicableActive Not RecruitingNCT04784494
What this trial is testing

MST for Parkinson's Disease

Who this might be right for
Parkinson DiseaseDepressionMovement Disorders+1 more
University of British Columbia 20
Not applicableStudy completedNCT00369746
What this trial is testing

STAR*D Alcohol: Treatment of Depression Concurrent With Alcohol Abuse

Who this might be right for
Major Depressive DisorderAlcohol Use Disorder
New York State Psychiatric Institute 674
Testing effectiveness (Phase 2)Study completedNCT04395183
What this trial is testing

5-HTP and Creatine for Depression

Who this might be right for
Major Depressive Disorder
University of Utah 43
Post-approval studies (Phase 4)Study completedNCT02393066
What this trial is testing

Comparison of Hemodynamics Between Dexmedetomidine and Propofol for Sedation in Patients With Abdominal Surgery

Who this might be right for
Disorder; Mental, SedativePain, PostoperativeSurgery
National Taiwan University Hospital 60
Next Page