Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Severe Osteoarthritis of the Knee”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT00669409
What this trial is testing

A Phase 1/2A, Single Dose Study Of PF-04383119 In Japanese Patients With Moderate To Severe Pain From Osteoarthritis Of The Knee

Who this might be right for
Osteoarthritis, Knee
Pfizer 83
Large-scale testing (Phase 3)Ended earlyNCT03285646
What this trial is testing

Evaluate the Efficacy and Safety of Fasinumab in Patients With Moderate-to-Severe Chronic Low Back Pain and Osteoarthritis of the Hip or Knee

Who this might be right for
Chronic Low Back PainOsteoarthritis
Regeneron Pharmaceuticals 63
Not applicableStudy completedNCT03719417
What this trial is testing

A Biologic Joint Replacement Strategy for Knee Trauma and Post-Traumatic Osteoarthritis

Who this might be right for
Knee OsteoarthritisPost-traumatic Osteoarthritis
University of Missouri-Columbia 14
Early research (Phase 1)Study completedNCT03513016
What this trial is testing

A Safety and Tolerability Study of UBX0101 in Patients With Osteoarthritis of the Knee

Who this might be right for
Osteoarthritis, Knee
Unity Biotechnology, Inc. 78
Large-scale testing (Phase 3)Study completedNCT05603754
What this trial is testing

Safety and Efficacy of Lorecivivint (SM04690) for the Treatment of Knee Osteoarthritis (STRIDES)

Who this might be right for
Knee Osteoarthritis
Biosplice Therapeutics, Inc. 499
Not applicableWithdrawnNCT04472091
What this trial is testing

Genicular Artery Embolization (GAE) for Osteoarthritic Knee Pain

Who this might be right for
Knee OsteoarthritisKnee Pain ChronicKnee Pain Swelling+2 more
Andrew Picel
Large-scale testing (Phase 3)Study completedNCT00421928
What this trial is testing

Tapentadol (CG5503)

Who this might be right for
Osteoarthritis, KneePain
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 1,030
Testing effectiveness (Phase 2)Study completedNCT06828666
What this trial is testing

A Phase 1/2a to Evaluate the Safety and Efficacy of Adipose Tissue Allograft (BRC-OA) in Patients With Osteoarthritis of the Knee

Who this might be right for
Osteoarthritis of Knee
Britecyte 46
Testing effectiveness (Phase 2)Study completedNCT02188771
What this trial is testing

A Phase I, Prospective, Randomized, Open-label, Active-Controlled Clinical Trial for Safety Evaluation of Intra-articular Injection of RegenoGel-SP for the Treatment of Moderate to Severe Osteoarthritis

Who this might be right for
Osteoarthritis
ProCore Ltd. 11
Testing effectiveness (Phase 2)Study completedNCT00819572
What this trial is testing

Study of Intra-articular DLX105 Applied to Patients With Severely Painful Osteoarthritis of the Knee

Who this might be right for
Osteoarthritis
ESBATech AG 27
Testing effectiveness (Phase 2)Study completedNCT01768975
What this trial is testing

Phase 2 Efficacy Trial of OLT1177 Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee

Who this might be right for
Osteoarthritis of the Knee
Olatec Therapeutics, Inc. 79
Not applicableNot Yet RecruitingNCT07403448
What this trial is testing

Effects of 9 Points Electrical Dry Needling in Knee Osteoarthritis

Who this might be right for
Knee Arthritis Osteoarthritis
Riphah International University 44
Large-scale testing (Phase 3)Study completedNCT03245008
What this trial is testing

Efficacy and Safety of MT-5547 in Patients With Osteoarthritis Accompanied by Moderate to Severe Pain

Who this might be right for
Osteoarthritis, Knee / Osteoarthritis, Hip
Tanabe Pharma Corporation 626
Testing effectiveness (Phase 2)Study completedNCT01688934
What this trial is testing

Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis (OA) of the Knee

Who this might be right for
Osteoarthritis, KneePain
Purdue Pharma LP 230
Early research (Phase 1)Study completedNCT00454298
What this trial is testing

Study Evaluating AGG-523 in Subjects With Severe Osteoarthritis Requiring Total Knee Replacement

Who this might be right for
Osteoarthritis
Wyeth is now a wholly owned subsidiary of Pfizer 2
Large-scale testing (Phase 3)Study completedNCT00980798
What this trial is testing

Placebo-controlled Trial With OROS Hydromorphone Hydrochloride to Treat Patients With Moderate to Severe Pain Induced by Osteoarthritis of the Hip or the Knee

Who this might be right for
PainOsteoarthritis, HipOsteoarthritis, Knee
Janssen-Cilag International NV 288
Not applicableLooking for participantsNCT05302934
What this trial is testing

Evaluation of the PHENO4U Data Platform in Patients Undergoing Total Knee Arthroplasty

Who this might be right for
Degenerative OsteoarthritisRheumatoid ArthritisPosttraumatic Arthropathy+3 more
Aesculap AG 600
Large-scale testing (Phase 3)Study completedNCT02462850
What this trial is testing

A Multi-Center Actual-Use Study on the Safety of CL 108 for the Treatment of Moderate to Severe Acute Pain Associated With Osteoarthritis of the Knee or Hip

Who this might be right for
PainNauseaVomiting
Charleston Laboratories, Inc 178
Large-scale testing (Phase 3)Study completedNCT00313846
What this trial is testing

Safety and Efficacy of Buprenorphine Transdermal System in Subjects With Moderate to Severe Osteoarthritis of Hip or Knee

Who this might be right for
Osteoarthritis
Purdue Pharma LP 529
Testing effectiveness (Phase 2)Looking for participantsNCT07308834
What this trial is testing

Evaluation of Intra-articular CX-011 to Treat Moderate to Severe Pain From Knee Osteoarthritis

Who this might be right for
Osteoarthritis of the Knees
CarthroniX, Inc. 72
Next Page