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Results for “Severe Sickle Cell Disease”

108 trials

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Showing 20 of 108 results

Very early researchLooking for participantsNCT06565026
What this trial is testing

CS-206 in Patients With Sickle Cell Disease

Who this might be right for
Sickle Cell Disease
CorrectSequence Therapeutics Co., Ltd 5
Not applicableLooking for participantsNCT06539169
What this trial is testing

FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases

Who this might be right for
Alpha-ThalassemiaBeta-ThalassemiaAmyloidosis+14 more
xCures 1,000
Testing effectiveness (Phase 2)Active Not RecruitingNCT03924401
What this trial is testing

Acute GVHD Suppression Using Costimulation Blockade to Expand Non-malignant Transplant

Who this might be right for
Graft Versus Host Disease
Emory University 30
Testing effectiveness (Phase 2)UnknownNCT02776202
What this trial is testing

HLA-Identical Sibling Donor Bone Marrow Transplantation for Individuals With Severe Sickle Cell Disease Using a Reduced Intensity Conditioning Regimen

Who this might be right for
Sickle Cell Disease
National Guard Health Affairs 15
Not applicableStudy completedNCT02242058
What this trial is testing

QST-Pupillometry in Sickle Cell Disease Patients

Who this might be right for
SCD With Severe Phenotype (HbSS, HbSβ0 Thalassemia, HbSOARab)
Julia Finkel 96
Not applicableLooking for participantsNCT07145411
What this trial is testing

HPC Offered for PRESERVE Expansion

Who this might be right for
Bone Marrow Transplant (BMT)
Ossium Health, Inc. 10
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Very early researchEnded earlyNCT03421756
What this trial is testing

Stem Cell Transplant in Patients With Severe Sickle Cell Disease

Who this might be right for
Sickle Cell Disease
Kathleen Dorritie 1
Testing effectiveness (Phase 2)Study completedNCT03240731
What this trial is testing

HLA Haploidentical Bone Marrow Transplant in Patients With Severe Sickle Cell Disease

Who this might be right for
Sickle Cell Disease
Centre Hospitalier Intercommunal Creteil 25
Testing effectiveness (Phase 2)Looking for participantsNCT03653338
What this trial is testing

T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

Who this might be right for
Sickle Cell AnemiaBeta-thalassemia MajorDiamond-blackfan Anemia
Paul Szabolcs 5
Not applicableActive Not RecruitingNCT05145062
What this trial is testing

Long - Term Follow Up of Sickle Cell Disease and Beta-thalassemia Subjects Previously Exposed to BIVV003 or ST-400.

Who this might be right for
Blood and Lymphatic Diseases
Sangamo Therapeutics 8
Testing effectiveness (Phase 2)Looking for participantsNCT03128996
What this trial is testing

Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders

Who this might be right for
Severe Sickle Cell DiseaseBone Marrow Failure SyndromesMetabolic Disorders+3 more
Washington University School of Medicine 29
Large-scale testing (Phase 3)Study completedNCT03745287
What this trial is testing

A Safety and Efficacy Study Evaluating CTX001 in Subjects With Severe Sickle Cell Disease

Who this might be right for
Sickle Cell DiseaseHematological DiseasesHemoglobinopathies
Vertex Pharmaceuticals Incorporated 63
Testing effectiveness (Phase 2)UnknownNCT03944447
What this trial is testing

Outcomes Mandate National Integration With Cannabis as Medicine

Who this might be right for
Chronic PainChronic Pain SyndromeChronic Pain Due to Injury+30 more
OMNI Medical Services, LLC 200,000
Testing effectiveness (Phase 2)Study completedNCT03634488
What this trial is testing

Management of Severe Acute Malnutrition in SCD, in Northern Nigeria

Who this might be right for
Sickle Cell AnemiaSevere Acute Malnutrition
Vanderbilt University Medical Center 132
Early research (Phase 1)Ended earlyNCT04443907
What this trial is testing

Study of Safety and Efficacy of Genome-edited Hematopoietic Stem and Progenitor Cells in Sickle Cell Disease (SCD)

Who this might be right for
Sickle Cell Disease
Novartis Pharmaceuticals 4
Testing effectiveness (Phase 2)Study completedNCT00745420
What this trial is testing

Evaluating the Safety and Effectiveness of Bone Marrow Transplants in Children With Sickle Cell Disease (BMT CTN 0601)

Who this might be right for
Sickle Cell Disease
Medical College of Wisconsin 30
Large-scale testing (Phase 3)UnknownNCT01511848
What this trial is testing

Study Of Efficacy,Safety of Combined Deferasirox and Deferiprone Versus Combined Deferiprone and Desferal In Conditions of Iron Overload

Who this might be right for
Beta-thalassemia MajorSickle Cell DiseaseIron Hemosiderosis
Ain Shams University 60
Early research (Phase 1)Looking for participantsNCT07015684
What this trial is testing

131I-apamistamab-based Conditioning for Hematopoietic Stem Cell Transplant (HSCT) in Advanced Sickle Cell Disease (SCD)

Who this might be right for
Sickling Disorder Due to Hemoglobin S
Columbia University 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT01966367
What this trial is testing

CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation

Who this might be right for
Bone Marrow Failure SyndromeSevere Aplastic AnemiaSevere Congenital Neutropenia+13 more
Diane George 37
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