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Results for “Sickle - Beta Thalassemia”

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Showing 20 of 0 results

Early research (Phase 1)Study completedNCT01039636
What this trial is testing

Safety and Pharmacokinetic Study of Escalating Multiple Doses of an Iron Chelator in Patients With Iron Overload

Who this might be right for
Transfusional Iron OverloadBeta-thalassemia
FerroKin BioSciences, Inc. 20
Early research (Phase 1)Study completedNCT00005783
What this trial is testing

A Phase I/II Trial of Recombinant-Methionyl Human Stem Cell Factor (SCF) in Adult Patients With Sickling Disorders

Who this might be right for
Hemoglobin SC DiseaseSickle Cell Anemia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT02105766
What this trial is testing

Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure

Who this might be right for
Sickle Cell DiseaseThalassemiaStem Cell Transplantation+1 more
National Heart, Lung, and Blood Institute (NHLBI) 56
Not applicableTemporarily Not AvailableNCT07640815
What this trial is testing

Expanded Access Protocol for Gene Therapy Utilizing shmiR Lentivirus Vector to Induce Fetal Hemoglobin in Sickle Cell Disease

Who this might be right for
Sickle Cell Disease
David Williams
Not applicableStudy completedNCT04678037
What this trial is testing

Home-based Assessment of PRO Measures in SCD Using A Smartphone App Platform: A Feasibility Study

Who this might be right for
Sickle Cell DiseaseSickle Cell Hemoglobin CSickle Beta Zero Thalassemia+1 more
Ann & Robert H Lurie Children's Hospital of Chicago 40
Not applicableEnrolling By InvitationNCT06664541
What this trial is testing

Decision-Making and Quality of Life Surrounding Hematologic Disease and Gene Therapy

Who this might be right for
Transfusion Dependent Beta ThalassemiaSickle Cell Disease
Georgetown University 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT00061568
What this trial is testing

Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias

Who this might be right for
Congenital Hemolytic AnemiaSickle Cell Disease
National Heart, Lung, and Blood Institute (NHLBI) 130
Early research (Phase 1)Study completedNCT01522547
What this trial is testing

Study to Determine the Maximum Tolerated Dose, Safety and Effectiveness of Pomalidomide for Patients With Sickle Cell Disease

Who this might be right for
Anemia, Sickle Cell
Celgene 12
Not applicableStudy completedNCT01715480
What this trial is testing

Effect of Broccoli Sprouts Homogenate on SS RBC

Who this might be right for
Sickle Red Blood CellFetal HemoglobinOxidative Stress
Duke University 21
Not applicableStudy completedNCT02197845
What this trial is testing

Enhancing Use of Hydroxyurea In Sickle Cell Disease Using Patient Navigators

Who this might be right for
Sickle Cell Disease
Virginia Commonwealth University 353
Testing effectiveness (Phase 2)Study completedNCT00004412
What this trial is testing

Phase II Randomized Trial:Arginine Butyrate Plus Standard Local Therapy in Patients With Refractory Sickle Cell Ulcers

Who this might be right for
Skin UlcersSickle Cell Anemia
Susan P. Perrine 23
Not applicableActive Not RecruitingNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Not applicableUnknownNCT01201135
What this trial is testing

GDF 15 in Sickle Cell Disease and Hereditary Spherocytosis

Who this might be right for
Patients With Thalassemia Intermedia,Congenital Dyserythropoietic Anemia Type I
Wolfson Medical Center 80
Testing effectiveness (Phase 2)Looking for participantsNCT07599176
What this trial is testing

Partial Stem Cell Transplant for Sickle Cell Disease From Matched Donors

Who this might be right for
Sickle Cell DiseaseBeta-thalassemia
National Heart, Lung, and Blood Institute (NHLBI) 90
Testing effectiveness (Phase 2)Active Not RecruitingNCT05353647
What this trial is testing

A Gene Transfer Study Inducing Fetal Hemoglobin in Sickle Cell Disease (GRASP, BMT CTN 2001)

Who this might be right for
Sickle Cell Disease
David Williams 25
Not applicableStudy completedNCT04523376
What this trial is testing

Pilot Study PBSCT With TCRab Depletion For Hemoglobinopathies

Who this might be right for
Sickle Cell DiseaseThalassemia Major
Timothy Olson 8
Early research (Phase 1)Study completedNCT02712346
What this trial is testing

The Role of Endothelin-1 in Sickle Cell Disease

Who this might be right for
Sickle Cell Anemia
Augusta University 26
Early research (Phase 1)Study completedNCT03492931
What this trial is testing

PK Study of Ticagrelor in Children Aged Less Than 24 Months, With Sickle Cell Disease (HESTIA4)

Who this might be right for
Sickle Cell Disease
AstraZeneca 21
Large-scale testing (Phase 3)Looking for participantsNCT05477563
What this trial is testing

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

Who this might be right for
Beta-ThalassemiaThalassemiaHematologic Diseases+4 more
Vertex Pharmaceuticals Incorporated 26
Testing effectiveness (Phase 2)Enrolling By InvitationNCT07401823
What this trial is testing

Open-Label Extension Study to Pioneer Study 6058-SCD-101

Who this might be right for
Sickle Cell Disease
Fulcrum Therapeutics 50
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