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Results for “Sickle Beta Plus Thalassemia”

52 trials

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Showing 20 of 52 results

Testing effectiveness (Phase 2)Study completedNCT03763656
What this trial is testing

Pharmacokinetics of Oral Hydroxyurea Solution

Who this might be right for
Sickle Cell DiseaseSickle-Cell; Hemoglobin Disease, ThalassemiaSickle Cell-beta-thalassemia+1 more
Nova Laboratories Limited 33
Testing effectiveness (Phase 2)Active Not RecruitingNCT00061568
What this trial is testing

Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias

Who this might be right for
Congenital Hemolytic AnemiaSickle Cell Disease
National Heart, Lung, and Blood Institute (NHLBI) 130
Not applicableStudy completedNCT00005893
What this trial is testing

Study of Allogeneic Bone Marrow Transplantation Using Matched, Related Donors in Patients With Nonmalignant Hematologic Disorders

Who this might be right for
NeutropeniaSickle Cell AnemiaThalassemia Major+1 more
Fairview University Medical Center
Not applicableLooking for participantsNCT04688411
What this trial is testing

An mHealth Strategy to Improve Medication Adherence in Adolescents With Sickle Cell Disease

Who this might be right for
Sickle Cell DiseaseSickle Beta Zero ThalassemiaSickle B+ Thalassemia+1 more
Ann & Robert H Lurie Children's Hospital of Chicago 40
Testing effectiveness (Phase 2)Study completedNCT00004412
What this trial is testing

Phase II Randomized Trial:Arginine Butyrate Plus Standard Local Therapy in Patients With Refractory Sickle Cell Ulcers

Who this might be right for
Skin UlcersSickle Cell Anemia
Susan P. Perrine 23
Testing effectiveness (Phase 2)Looking for participantsNCT04008368
What this trial is testing

Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myeloid Chimerism Levels

Who this might be right for
Myeloid Chimerism
National Heart, Lung, and Blood Institute (NHLBI) 32
Testing effectiveness (Phase 2)Ended earlyNCT01363908
What this trial is testing

Safety, Efficacy and Pharmacokinetics of an Oral Iron Chelator Given for a Year to Pediatric Patients With Iron Overload

Who this might be right for
Transfusional Iron OverloadBeta-Thalassemia
Shire 30
Post-approval studies (Phase 4)Study completedNCT00749515
What this trial is testing

Pilot Study for Patients With Poor Response to Deferasirox

Who this might be right for
Transfusion-dependent HemachromatosisThalassemia MajorSickle Cell Disease
Boston Children's Hospital 15
Not applicableActive Not RecruitingNCT04523376
What this trial is testing

Pilot Study PBSCT with TCRab Depletion for Hemoglobinopathies

Who this might be right for
Sickle Cell DiseaseThalassemia Major
Timothy Olson 9
Not applicableActive Not RecruitingNCT04691323
What this trial is testing

The Longitudinal Relationship of HU Adherence to HRQOL, Barriers to Adherence and Habit in SCD.

Who this might be right for
Sickle Cell DiseaseSickle B+ ThalassemiaSickle Beta Zero Thalassemia+1 more
Ann & Robert H Lurie Children's Hospital of Chicago 68
Testing effectiveness (Phase 2)Study completedNCT02151526
What this trial is testing

A Study Evaluating the Safety and Efficacy of LentiGlobin BB305 Drug Product in β-Thalassemia Major (Also Referred to as Transfusion-dependent β-Thalassemia [TDT]) and Sickle Cell Disease

Who this might be right for
Beta-Thalassemia MajorSickle Cell Disease
Genetix Biotherapeutics Inc. 7
Testing effectiveness (Phase 2)Active Not RecruitingNCT05357482
What this trial is testing

Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia

Who this might be right for
Sickle Cell AnemiaBeta Thalassemia
National Heart, Lung, and Blood Institute (NHLBI) 40
Large-scale testing (Phase 3)Enrolling By InvitationNCT04208529
What this trial is testing

A Long-term Follow-up Study in Participants Who Received CTX001

Who this might be right for
Beta-ThalassemiaThalassemiaSickle Cell Disease+4 more
Vertex Pharmaceuticals Incorporated 160
Testing effectiveness (Phase 2)Active Not RecruitingNCT00408447
What this trial is testing

Stem Cell Transplant in Sickle Cell Disease and Thalassemia

Who this might be right for
Sickle Cell DiseaseBeta Thalassemia
Columbia University 53
Very early researchWithdrawnNCT04776850
What this trial is testing

Pre-transplant Immunosuppression and Donor Stem Cell Transplant for the Treatment of Severe Hemoglobinopathies

Who this might be right for
Beta Thalassemia MajorSickle Beta 0 ThalassemiaSickle Beta Plus Thalassemia+3 more
M.D. Anderson Cancer Center
Not applicableLooking for participantsNCT06539169
What this trial is testing

FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases

Who this might be right for
Alpha-ThalassemiaBeta-ThalassemiaAmyloidosis+14 more
xCures 1,000
Not applicableActive Not RecruitingNCT05145062
What this trial is testing

Long - Term Follow Up of Sickle Cell Disease and Beta-thalassemia Subjects Previously Exposed to BIVV003 or ST-400.

Who this might be right for
Blood and Lymphatic Diseases
Sangamo Therapeutics 8
Early research (Phase 1)Study completedNCT03492931
What this trial is testing

PK Study of Ticagrelor in Children Aged Less Than 24 Months, With Sickle Cell Disease (HESTIA4)

Who this might be right for
Sickle Cell Disease
AstraZeneca 21
Not applicableStudy completedNCT06831799
What this trial is testing

ERN-EuroBloodNet Registry on Patients With Rare Red Blood Cell Defects and COVID-19

Who this might be right for
HemoglobinopathiesSickle Cell DiseaseSickle Cell Anemia+21 more
Hospital Universitari Vall d'Hebron Research Institute 684
Testing effectiveness (Phase 2)Active Not RecruitingNCT02105766
What this trial is testing

Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure

Who this might be right for
Sickle Cell DiseaseThalassemiaStem Cell Transplantation+1 more
National Heart, Lung, and Blood Institute (NHLBI) 56
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