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Results for “Sickle Beta Plus Thalassemia”

53 trials

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Showing 20 of 53 results

Not applicableStudy completedNCT01931644
What this trial is testing

At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions

Who this might be right for
All Diagnosed Health ConditionsADD/ADHDAlopecia Areata+58 more
Sanguine Biosciences 17,667
Testing effectiveness (Phase 2)UnknownNCT00061568
What this trial is testing

Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias

Who this might be right for
Congenital Hemolytic AnemiaSickle Cell Disease
National Heart, Lung, and Blood Institute (NHLBI) 130
Testing effectiveness (Phase 2)Study completedNCT02151526
What this trial is testing

A Study Evaluating the Safety and Efficacy of LentiGlobin BB305 Drug Product in β-Thalassemia Major (Also Referred to as Transfusion-dependent β-Thalassemia [TDT]) and Sickle Cell Disease

Who this might be right for
Beta-Thalassemia MajorSickle Cell Disease
Genetix Biotherapeutics Inc. 7
Early research (Phase 1)Looking for participantsNCT05904093
What this trial is testing

Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell Disease

Who this might be right for
Sickle Cell DiseaseHb-SS DiseaseHemoglobin S+3 more
National Heart, Lung, and Blood Institute (NHLBI) 25
Testing effectiveness (Phase 2)Study completedNCT01186419
What this trial is testing

Safety and Pharmacodynamic Study of an Oral Iron Chelator Given for 6 Months to Patients With Iron Overload

Who this might be right for
Transfusional Iron OverloadBeta-thalassemia
Shire 51
Testing effectiveness (Phase 2)Ended earlyNCT01363908
What this trial is testing

Safety, Efficacy and Pharmacokinetics of an Oral Iron Chelator Given for a Year to Pediatric Patients With Iron Overload

Who this might be right for
Transfusional Iron OverloadBeta-Thalassemia
Shire 30
Testing effectiveness (Phase 2)Looking for participantsNCT01962415
What this trial is testing

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+4 more
Paul Szabolcs 100
Testing effectiveness (Phase 2)Looking for participantsNCT02675959
What this trial is testing

Myeloablative Conditioning, Prophylactic Defibrotide and Haplo AlloSCT for Patients With Sickle Cell Disease

Who this might be right for
Sickle Cell Disease
New York Medical College 40
Testing effectiveness (Phase 2)Study completedNCT03763656
What this trial is testing

Pharmacokinetics of Oral Hydroxyurea Solution

Who this might be right for
Sickle Cell DiseaseSickle-Cell; Hemoglobin Disease, ThalassemiaSickle Cell-beta-thalassemia+1 more
Nova Laboratories Limited 33
Testing effectiveness (Phase 2)Looking for participantsNCT05736419
What this trial is testing

Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT)

Who this might be right for
Sickle Cell DiseaseThalassemia, BetaThalassemia
Memorial Sloan Kettering Cancer Center 24
Not applicableLooking for participantsNCT06213402
What this trial is testing

RADeep Multicenter European Epidemiological Platform for Patients Diagnosed With Rare Anemia Disorders (RADs)

Who this might be right for
Sickle Cell DiseaseThalassemiaHemolytic; Anemia, Hereditary, Due to Enzyme Disorder+6 more
Hospital Universitari Vall d'Hebron Research Institute 32,564
Testing effectiveness (Phase 2)Active Not RecruitingNCT00408447
What this trial is testing

Stem Cell Transplant in Sickle Cell Disease and Thalassemia

Who this might be right for
Sickle Cell DiseaseBeta Thalassemia
Columbia University 53
Not applicableUnknownNCT00596999
What this trial is testing

A Single-arm Safety Study of Transplantation Using Umbilical Cord Blood and Human Placental-derived Stem Cells From Partially Matched Related Donors in Persons With Certain Malignant Blood Diseases and Non-malignant Disorders

Who this might be right for
Hematologic Malignancies
Celgene Corporation 6
Not applicableLooking for participantsNCT04688411
What this trial is testing

An mHealth Strategy to Improve Medication Adherence in Adolescents With Sickle Cell Disease

Who this might be right for
Sickle Cell DiseaseSickle Beta Zero ThalassemiaSickle B+ Thalassemia+1 more
Ann & Robert H Lurie Children's Hospital of Chicago 40
Early research (Phase 1)Study completedNCT01917708
What this trial is testing

Bone Marrow Transplant With Abatacept for Non-Malignant Diseases

Who this might be right for
Hurler SyndromeFanconi AnemiaGlanzmann Thrombasthenia+12 more
Emory University 10
Very early researchWithdrawnNCT04776850
What this trial is testing

Pre-transplant Immunosuppression and Donor Stem Cell Transplant for the Treatment of Severe Hemoglobinopathies

Who this might be right for
Beta Thalassemia MajorSickle Beta 0 ThalassemiaSickle Beta Plus Thalassemia+3 more
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Study completedNCT02435901
What this trial is testing

HSCT For Patients With High Risk Hemoglobinopathies Using Reduced Intensity

Who this might be right for
Sickle Cell DiseaseBeta Thalassemia-Major
Northwell Health 29
Large-scale testing (Phase 3)Enrolling By InvitationNCT04208529
What this trial is testing

A Long-term Follow-up Study in Participants Who Received CTX001

Who this might be right for
Beta-ThalassemiaThalassemiaSickle Cell Disease+4 more
Vertex Pharmaceuticals Incorporated 160
Not applicableLooking for participantsNCT06539169
What this trial is testing

FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases

Who this might be right for
Alpha-ThalassemiaBeta-ThalassemiaAmyloidosis+14 more
xCures 1,000
Testing effectiveness (Phase 2)Ended earlyNCT01000155
What this trial is testing

Efficacy of Vorinostat to Induce Fetal Hemoglobin in Sickle Cell Disease

Who this might be right for
Sickle Cell DiseaseSickle Cell Anemia
Dana-Farber Cancer Institute 5
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